{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:03:06Z","timestamp":1785430986652,"version":"3.56.0"},"reference-count":23,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Objectives: To assess how differences in keratometric measurement principles affect intraocular lens (IOL) power calculation, we compared front-surface reflection-based (FSR) and anterior segment optical coherence tomography (AS-OCT)-derived keratometry (K) values. Methods: This retrospective study included 160 eyes of 160 Japanese patients who underwent cataract surgery with implantation of a CNA0T0 (Alcon) IOL between March 2023 and October 2025. FSR-based keratometry (OA-K, 2.5 mm averaged output ring) was obtained using the OA-2000 (Tomey), whereas AS-OCT-derived keratometry (CA-K, 2.5 mm single ring) and Fourier keratometry (CA-FK, 3.0 mm Fourier analysis zone) were obtained using CASIA2 (Tomey). Predicted refractions were calculated using Barrett Universal II (B-UII) and SRK\/T formulas with each K value. Results: Mean K values were 44.14 \u00b1 1.51 D (OA-K), 44.28 \u00b1 1.51 D (CA-K), and 44.40 \u00b1 1.55 D (CA-FK). With the B-UII, the mean absolute error (MAE) was lowest with OA-K (0.27 \u00b1 0.24 D), followed by CA-K (0.28 \u00b1 0.22 D) and CA-FK (0.31 \u00b1 0.23 D). Corresponding MAEs with SRK\/T were 0.30 \u00b1 0.26 D, 0.31 \u00b1 0.24 D, and 0.33 \u00b1 0.28 D, respectively. Exploratory subgroup analyses suggested a tendency toward lower prediction accuracy in steep corneas. Differences among keratometric methods were smaller with SRK\/T than with B-UII. Conclusions: AS-OCT-derived keratometry did not demonstrate superiority over conventional FSR-based keratometry for IOL power calculation. Further studies are warranted to determine whether AS-OCT-derived keratometry may provide clinical advantages under specific conditions.<\/jats:p>","DOI":"10.3390\/jcm15155968","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:15:00Z","timestamp":1785428100000},"page":"5968","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact and Limitations of Front-Surface Reflection-Based and Anterior Segment OCT-Derived Keratometry on Refractive Prediction Accuracy in Intraocular Lens Power Calculation"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4538-8523","authenticated-orcid":false,"given":"Sumitaka","family":"Miyamoto","sequence":"first","affiliation":[{"name":"Aira Miyamoto Eye Clinic, Aira 8995213, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutaka","family":"Kamiya","sequence":"additional","affiliation":[{"name":"School of Rehabilitation Sciences, Showa Medical University, Yokohama 2268555, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"ref_1","first-page":"1547","article-title":"Improved prediction of intraocular lens power using partial coherence interferometry","volume":"24","author":"Drexler","year":"1998","journal-title":"J. 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