{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T12:30:28Z","timestamp":1786365028312,"version":"build-2736575974"},"reference-count":19,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objective: Whereas conventional flanged intrascleral fixation is limited to 3-piece intraocular lenses (IOLs), we developed and evaluated a novel haptic-extended flange technique for single-piece acrylic IOLs, including presbyopia-correcting and toric lenses. Methods: In this technique, a 6-0 polypropylene suture is secured along the lateral aspect of the single-piece IOL haptic to extend its length, followed by intrascleral flange fixation. Uncorrected visual acuity (UCVA) from far to near, corrected distance visual acuity (CDVA), and refraction were evaluated at 1 month postoperatively. IOL tilt and decentration were assessed using anterior segment optical coherence tomography. Results: This study included a consecutive series of 10 eyes of 10 patients (mean age: 58.3 \u00b1 16.2 years), comprising 5 eyes with multifocal IOL, 2 eyes with multifocal toric IOL, 2 eyes with enhanced monofocal IOL, and 1 eye with monofocal IOL. All IOLs were securely fixed; the mean IOL tilt was 5.74 \u00b1 2.93\u00b0 and the mean decentration was 0.35 \u00b1 0.19 mm. All eyes achieved CDVA of 20\/20 or better, and all eyes with multifocal IOLs achieved UCVA at 40 cm of 20\/25 or better. No early postoperative complications attributable to the surgical procedure were observed. In a case associated with atopic dermatitis, retinal detachment occurred 4 months after surgery. Conclusions: In this preliminary case series, haptic-extended flange fixation enabled early stabilization of selected single-piece acrylic IOLs with favorable short-term visual and anatomic outcomes. Larger studies with longer follow-up are needed to confirm long-term safety, durability and comparative effectiveness.<\/jats:p>","DOI":"10.3390\/jcm15166190","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T11:38:09Z","timestamp":1786361889000},"page":"6190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Haptic-Extended Flange Intrascleral Fixation for Single-Piece Acrylic Intraocular Lenses"],"prefix":"10.3390","volume":"15","author":[{"given":"Ayako","family":"Eno","sequence":"first","affiliation":[{"name":"Eno Eye Clinic NishiAshiya, Ashiya 659-0085, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Chung","family":"Chang","sequence":"additional","affiliation":[{"name":"Eno Eye Clinic NishiAshiya, Ashiya 659-0085, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9071-7018","authenticated-orcid":false,"given":"Tetsuro","family":"Oshika","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba 305-8575, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.ophtha.2017.03.036","article-title":"Flanged intrascleral intraocular lens fixation with double-needle technique","volume":"124","author":"Yamane","year":"2017","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.2147\/OPTH.S276226","article-title":"Scleral fixation of single-piece foldable IOL using double-flanged technique","volume":"14","author":"Samir","year":"2020","journal-title":"Clin. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/j.jcrs.0000000000000845","article-title":"Punch and rescue technique for scleral fixation of dislocated single-piece intraocular lenses","volume":"48","author":"Micheletti","year":"2022","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"455","DOI":"10.4103\/IJO.IJO_1960_24","article-title":"Three-point flanged optic piercing intrascleral fixation of multifocal intraocular lenses","volume":"73","author":"Eom","year":"2025","journal-title":"Indian J. Ophthalmol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"S142","DOI":"10.4103\/IJO.IJO_2536_25","article-title":"Modified ab externo 2-point pierce technique for scleral fixation of single-piece intraocular lenses","volume":"74","author":"Tendulkar","year":"2026","journal-title":"Indian J. Ophthalmol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/IAE.0000000000004103","article-title":"Microforceps-assisted transscleral fixation of intraocular lens","volume":"45","author":"Li","year":"2025","journal-title":"Retina"},{"key":"ref_7","first-page":"e89566","article-title":"Suture Repositioning for subluxation of a toric-type single-piece multifocal intraocular kens","volume":"17","author":"Mito","year":"2025","journal-title":"Cureus"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"S137","DOI":"10.4103\/IJO.IJO_2503_25","article-title":"Scleral fixation of toric intraocular lenses\u2014A modified ab-externo 4-point fixation technique","volume":"74","author":"Hirawat","year":"2026","journal-title":"Indian J. Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.2147\/OPTH.S268126","article-title":"Comparison of clinical outcomes between intracapsular implantation and intrascleral fixation using the same model of intraocular lens","volume":"14","author":"Torii","year":"2020","journal-title":"Clin. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s40662-023-00341-6","article-title":"Refractive outcome and lens power calculation after intrascleral intraocular lens fixation: A comparison of three-piece and one-piece intrascleral fixation technique","volume":"10","author":"Schranz","year":"2023","journal-title":"Eye Vis."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Wang, X., Su, M., Li, Y., Xie, H., Sun, X., and Jiang, F. (2024). Application of modified Yamane technique in intrascleral intraocular lens fixation combined with or without iris reconstruction. BMC Ophthalmol., 24.","DOI":"10.1186\/s12886-024-03493-8"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1177\/11206721251357124","article-title":"Intraocular lens stability and factors affecting refractive error following modified Yamane technique without trimmed haptics","volume":"35","author":"Koutari","year":"2025","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Velarde-Rodriguez, G., Garcia-Onrubia, L., S\u00e1nchez-Lozano, A., Salgueiro-Tielas, L., Moreno-Rodr\u00edguez, L., Faria-Ribeiro, M., and Alejandre-Alba, N. (2025). Clinical impact of intraocular lens tilt and decentration: A cross-sectional study. BMC Ophthalmol., 25.","DOI":"10.1186\/s12886-025-04396-y"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"921","DOI":"10.21037\/atm-20-1008","article-title":"Determinants of intraocular lens tilt and decentration after cataract surgery","volume":"8","author":"Gu","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Kimura, S., Morizane, Y., Shiode, Y., Hirano, M., Doi, S., Toshima, S., Fujiwara, A., and Shiraga, F. (2017). Assessment of tilt and decentration of crystalline lens and intraocular lens relative to the corneal topographic axis using anterior segment optical coherence tomography. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0184066"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Zhang, Y., Zhang, J., Liang, C., Xu, Y., Wu, J., Wu, J., Zhang, Y., Jin, A., Tan, X., and Luo, L. (2025). Effect of crystalline lens decentration and tilt on visual performance in eyes implanted with bifocal or extended depth of focus intraocular lenses. BMC Ophthalmol., 25.","DOI":"10.1186\/s12886-025-03884-5"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Ashena, Z., Maqsood, S., Ahmed, S.N., and Nanavaty, M.A. (2020). Effect of intraocular lens tilt and decentration on visual acuity, dysphotopsia and wavefront aberrations. Vision, 4.","DOI":"10.3390\/vision4030041"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1080\/09273948.2016.1231328","article-title":"Transconjunctival sutureless intrascleral fixation of secondary intraocular lenses in patients with uveitis","volume":"26","author":"Todorich","year":"2018","journal-title":"Ocul. Immunol. Inflamm."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"402","DOI":"10.4103\/ijo.IJO_731_21","article-title":"Uveitis-glaucoma-hyphema syndrome following sutureless scleral fixated intraocular lens: A case report","volume":"2","author":"Sindal","year":"2022","journal-title":"Indian J. Ophthalmol. Case Rep."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/16\/6190\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T11:53:02Z","timestamp":1786362782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/16\/6190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,10]]},"references-count":19,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["jcm15166190"],"URL":"https:\/\/doi.org\/10.3390\/jcm15166190","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,10]]}}}