{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T10:26:27Z","timestamp":1787135187263,"version":"build-2736575974"},"reference-count":28,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background: Body mass index (BMI) is an important consideration in perioperative evaluation. High BMI is correlated with more comorbidities and poorer operative outcomes; however, there is limited literature on the impact of BMI on patient-reported outcome measures (PROMs) after multilevel cervical disc replacement (CDR) surgery. Objective: The objective was to evaluate the relationship between BMI and PROMs in two-level CDR. Methods: A single-surgeon database was retrospectively reviewed for patients who underwent two-level CDR between August 2017 and October 2024. Patients were stratified as non-obese (BMI &lt; 30 kg\/m2; n = 44) or obese (BMI \u2265 30 kg\/m2; n = 34). The final analytic cohort included 78 patients. Mean follow-up was 7.65 \u00b1 5.53 months. Multivariable linear and logistic regression models adjusted for age, hypertension, diabetes, and Charlson Comorbidity Index. Patient-reported outcome measures (PROMs) and minimal clinically important difference (MCID) were also analyzed. Statistical analysis was conducted using Stata 18.0 (StataCorp LP, College Station, TX, USA). Results: Obese patients had a higher CCI than non-obese patients (0.90 \u00b1 1.06, 1.87 \u00b1 1.31, p = 0.001). Patient-reported outcomes were collected and analyzed after controlling for hypertension, diabetes, CCI scores, and age. At the final postoperative follow-up, only VR12-MCS differed, with the obese cohort having worse scores (60.7 \u00b1 5.0 versus 53.9 \u00b1 10.2, p = 0.040). MCID achievement rates did not differ between groups across PROMs (p &gt; 0.183 for all). Conclusion: Patients with and without obesity demonstrated comparable early-to-midterm PROM trajectories and MCID achievement following two-level CDR. These findings suggest that obesity was not associated with substantially different patient-reported recovery during the observed follow-up period.<\/jats:p>","DOI":"10.3390\/jcm15166407","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T09:30:53Z","timestamp":1787131853000},"page":"6407","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Obesity on Patient-Reported Outcomes Following Two-Level Cervical Disc Replacement"],"prefix":"10.3390","volume":"15","author":[{"given":"Sloane O.","family":"Ward","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puranjay","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreya","family":"Kurup","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2751-1529","authenticated-orcid":false,"given":"Maximillian Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipankar","family":"Yettapu","sequence":"additional","affiliation":[{"name":"Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5824-7271","authenticated-orcid":false,"given":"Rohit","family":"Rajput","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Truong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline","family":"Sandberg","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonah","family":"Dujovny","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya S.","family":"Mazmudar","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, MedStar Georgetown University Hospital, Washington, DC 20007, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash J.","family":"Sayari","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel K.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kern","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"107619","DOI":"10.1016\/j.clineuro.2023.107619","article-title":"Impact of obesity on complications and surgical outcomes after adult degenerative scoliosis spine surgery","volume":"226","author":"Barrie","year":"2023","journal-title":"Clin. Neurol. 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