{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T09:25:18Z","timestamp":1787217918975,"version":"build-2736575974"},"reference-count":39,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research","award":["23K08521"],"award-info":[{"award-number":["23K08521"]}]},{"name":"European Union\u2019s Horizon 2020 research and innovation programme","award":["101034252"],"award-info":[{"award-number":["101034252"]}]},{"name":"Insight Research Ireland Centre for Data Analytics","award":["12\/RC\/2289_P2"],"award-info":[{"award-number":["12\/RC\/2289_P2"]}]},{"award":["12\/RC\/2289_P2"],"award-info":[{"award-number":["12\/RC\/2289_P2"]}],"id":[{"id":"https:\/\/ror.org\/03c01dw55","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Subarachnoid hemorrhage (SAH) is frequently complicated by cerebral vasospasm (VS). Clazosentan reduces VS, and fasudil hydrochloride hydrate (Fasudil) is widely used for VS prevention in Japan. However, the benefit of adding Fasudil to clazosentan remains unclear. We investigated whether adjunctive Fasudil was associated with VS-related and functional outcomes in clazosentan-treated aneurysmal SAH. Methods: We retrospectively analyzed data from the multicenter \u201cDatabase of Cohort Study for Outcome of SAH in Japan,\u201d collected from 2020 to 2024. Patients with aneurysmal SAH who underwent surgical clipping or endovascular coiling within 4 days of onset and completed 14 days of clazosentan treatment were included. Outcomes were compared between clazosentan plus Fasudil and clazosentan alone. Multivariable logistic regression assessed factors associated with angiographic vasospasm (AVS), cerebral infarction, and poor functional outcome (modified Rankin Scale 3\u20136) at discharge and 6 months. Results: Among 341 patients, 100 (29.3%) received adjunctive Fasudil and 241 (70.7%) clazosentan alone. AVS occurred in 58\/329 (17.6%), cerebral infarction in 58\/327 (17.7%), poor functional outcome at discharge in 142\/341 (41.6%), and poor functional outcome at 6 months in 82\/325 (25.2%). Adjunctive Fasudil was independently associated with higher odds of AVS (adjusted odds ratio [aOR] 2.41, 95% confidence interval [CI] 1.21\u20134.81), cerebral infarction (aOR 2.10, 95% CI 1.08\u20134.09), and poor 6-month outcome (aOR 2.88, 95% CI 1.08\u20137.71), but not with poor functional outcome at discharge (aOR 1.37, 95% CI 0.62\u20133.03). Conclusions: In clazosentan-treated aneurysmal SAH, adjunctive Fasudil use was not associated with additional benefit and was associated with higher odds of AVS, cerebral infarction, and poor functional outcome at 6 months.<\/jats:p>","DOI":"10.3390\/jcm15166424","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T16:12:58Z","timestamp":1787155978000},"page":"6424","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adjunctive Fasudil Use and Outcomes After Clazosentan Treatment for Aneurysmal Subarachnoid Hemorrhage: A Multicenter DCI Japan Registry Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9055-6666","authenticated-orcid":false,"given":"Shingo","family":"Matsuda","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Hiroshima, Japan"},{"name":"Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo 693-8555, Shimane, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0192-5430","authenticated-orcid":false,"given":"Masahito","family":"Katsuki","sequence":"additional","affiliation":[{"name":"Physical Education and Health Center, Nagaoka University of Technology, Nagaoka 940-2137, Niigata, Japan"},{"name":"Insight Research Ireland Centre for Data Analytics, School of Health and Human Performance, Dublin City University, D09 YT18 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo 693-8555, Shimane, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshikazu","family":"Hidaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo 693-8555, Shimane, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5852-0146","authenticated-orcid":false,"given":"Yasuhiko","family":"Matsumori","sequence":"additional","affiliation":[{"name":"Sendai Headache and Neurology Clinic, Sendai 982-0014, Miyagi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7139-695X","authenticated-orcid":false,"given":"Daizo","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsumi","family":"Takizawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Japanese Red Cross Asahikawa Hospital, Asahikawa 070-0061, Hokkaido, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2433-924X","authenticated-orcid":false,"given":"Yoji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kyorin University, Mitaka 181-8611, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kurashiki Central Hospital, Kurashiki 710-0052, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7179-1258","authenticated-orcid":false,"given":"Motohiro","family":"Morioka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kurume University School of Medicine, Kurume 830-0011, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kurita","sequence":"additional","affiliation":[{"name":"Department of Cerebrovascular Surgery, Saitama Medical University International Medical Center, Hidaka 350-1298, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1826-1914","authenticated-orcid":false,"given":"Akihiro","family":"Hirayama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokai University, Isehara 259-1193, Kanagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koreaki","family":"Irie","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Japan Red Cross Medical Center, Shibuya-ku 150-8935, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8909-2949","authenticated-orcid":false,"given":"Ichiro","family":"Nakahara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Fukuoka Shin Mizumaki Hospital, Mizumaki 807-0051, Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Horie","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4205-1490","authenticated-orcid":false,"given":"Fusao","family":"Ikawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo 693-8555, Shimane, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e1819","DOI":"10.1212\/WNL.0000000000010618","article-title":"Short- and Long-Term Outcome of Patients with Aneurysmal Subarachnoid Hemorrhage","volume":"95","author":"Roquer","year":"2020","journal-title":"Neurology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"231","DOI":"10.2176\/jns-nmc.2021-0249","article-title":"Japanese Subarachnoid Aneurysm Trial of Neurosurgical Clipping versus Endovascular Coiling in 1863 Patients with Ruptured Intracranial Aneurysms","volume":"62","author":"Irie","year":"2022","journal-title":"Neurol. Med. Chir."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s40120-022-00436-7","article-title":"Clinical Burden of Angiographic Vasospasm and Its Complications after Aneurysmal Subarachnoid Hemorrhage: A Systematic Review","volume":"12","author":"Chalet","year":"2023","journal-title":"Neurol. Ther."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1161\/STROKEAHA.108.191395","article-title":"Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage","volume":"40","author":"Bederson","year":"2009","journal-title":"Stroke"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1161\/STROKEAHA.123.043976","article-title":"Nimodipine Reduces Microvasospasms after Experimental Subarachnoid Hemorrhage","volume":"54","author":"Schwarting","year":"2023","journal-title":"Stroke"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.surneu.2006.10.037","article-title":"A Postmarketing Surveillance Study of Fasudil Treatment after Aneurysmal Subarachnoid Hemorrhage","volume":"68","author":"Suzuki","year":"2007","journal-title":"Surg. Neurol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S1474-4422(11)70108-9","article-title":"Clazosentan, an Endothelin Receptor Antagonist, in Patients with Aneurysmal Subarachnoid Haemorrhage Undergoing Surgical Clipping: A Randomised, Double-Blind, Placebo-Controlled Phase 3 Trial (CONSCIOUS-2)","volume":"10","author":"Macdonald","year":"2011","journal-title":"Lancet Neurol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1161\/STROKEAHA.111.648980","article-title":"Randomized Trial of Clazosentan in Patients with Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling","volume":"43","author":"MacDonald","year":"2012","journal-title":"Stroke"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1161\/STROKEAHA.108.519942","article-title":"Clazosentan to Overcome Neurological Ischemia and Infarction Occurring after Subarachnoid Hemorrhage (CONSCIOUS-1): Randomized, Double-Blind, Placebo-Controlled Phase 2 Dose-Finding Trial","volume":"39","author":"MacDonald","year":"2008","journal-title":"Stroke"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3171\/2024.4.JNS232191","article-title":"REACT: A Randomized Trial to Assess the Efficacy and Safety of Clazosentan for Preventing Clinical Deterioration Due to Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage","volume":"142","author":"Mayer","year":"2025","journal-title":"J. Neurosurg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.3171\/2022.2.JNS212914","article-title":"Effects of Clazosentan on Cerebral Vasospasm-Related Morbidity and All-Cause Mortality after Aneurysmal Subarachnoid Hemorrhage: Two Randomized Phase 3 Trials in Japanese Patients","volume":"137","author":"Endo","year":"2022","journal-title":"J. Neurosurg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s10143-025-03394-4","article-title":"Effects of the Japanese Traditional Medicine Goreisan on Adverse Events Affecting Mucosal Edema in Patients with Subarachnoid Hemorrhage Treated with Clazosentan","volume":"48","author":"Akamatsu","year":"2025","journal-title":"Neurosurg. Rev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"108296","DOI":"10.1016\/j.jstrokecerebrovasdis.2025.108296","article-title":"Risk Factors for Clazosentan-Induced Fluid Retention in Subarachnoid Hemorrhage from the Japanese Adverse Event Database","volume":"34","author":"Kawada","year":"2025","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2176\/jns-nmc.2024-0204","article-title":"Impact of Clazosentan on Vasospasm Reduction and Functional Recovery after Aneurysmal Subarachnoid Hemorrhage","volume":"65","author":"Kajiwara","year":"2025","journal-title":"Neurol. Med. Chir."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Kondo, H., Ishii, D., Kuwabara, M., Hara, T., Kurisu, K., Sumida, M., Ikawa, F., Ohba, S., Tominaga, A., and Obayashi, N. (2025). Multicenter Validation of a Unified Evidence-Based Treatment Protocol Focusing on Clazosentan for Managing Subarachnoid Hemorrhage. J. Clin. Med., 14.","DOI":"10.3390\/jcm14103423"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"100253","DOI":"10.1016\/j.wnsx.2023.100253","article-title":"Initial Real-World Experience of Clazosentan for Subarachnoid Hemorrhage in Japan","volume":"21","author":"Maeda","year":"2024","journal-title":"World Neurosurg. X"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10143-024-02345-9","article-title":"Comparison of Efficacy between Clazosentan and Fasudil Hydrochloride-Based Management of Vasospasm after Subarachnoid Hemorrhage Focusing on Older and WFNS Grade V Patients: A Single-Center Experience in Japan","volume":"47","author":"Mochizuki","year":"2024","journal-title":"Neurosurg. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s10143-023-02104-2","article-title":"Real-World Data of Clazosentan in Combination Therapy for Aneurysmal Subarachnoid Hemorrhage: A Multicenter Retrospective Cohort Study","volume":"46","author":"Muraoka","year":"2023","journal-title":"Neurosurg. Rev."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"624","DOI":"10.3171\/2025.1.JNS242509","article-title":"RECOVER Study: A Multicenter Retrospective Cohort Study and Comparison of the Efficacy and Safety of Clazosentan and Fasudil in Patients with Aneurysmal Subarachnoid Hemorrhage","volume":"143","author":"Muraoka","year":"2025","journal-title":"J. Neurosurg."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Mutoh, T., Aono, H., Seto, W., Kimoto, T., Tochinai, R., Moroi, J., and Ishikawa, T. (2024). Cardiopulmonary Events of the Elderly (\u226575 Years) during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan. Medicina, 60.","DOI":"10.3390\/medicina60010185"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"e943303-1\u2013e943303-7","DOI":"10.12659\/MSM.943303","article-title":"Factors Influencing Discontinuation of Clazosentan Therapy in Elderly Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study from a Japanese Single Center","volume":"30","author":"Mutoh","year":"2024","journal-title":"Med. Sci. Monit."},{"key":"ref_22","first-page":"e79497","article-title":"Treatment Outcomes of Clazosentan Use during the Perioperative Period for Subarachnoid Hemorrhage","volume":"17","author":"Okumura","year":"2025","journal-title":"Cureus"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Sakata, H., Kanoke, A., Uchida, H., Haryu, S., Omodaka, S., Kimura, N., Yoshida, M., Niizuma, K., Tominaga, T., and Endo, H. (2024). Prophylactic Management of Cerebral Vasospasm with Clazosentan in Real Clinical Practice: A Single-Center Retrospective Cohort Study. Front. Neurol., 15.","DOI":"10.3389\/fneur.2024.1413632"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1177\/0271678X251399068","article-title":"Stratified Assessment of Clazosentan Efficacy Following Subarachnoid Hemorrhage: A Multi-Center Cohort Study","volume":"46","author":"Sakata","year":"2026","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Sekimoto, M., Imai, T., Suzuki, Y., Ihara, S., Chiba, N., and Otani, N. (Neurol. Res., 2025). Risk Factors for Fluid Retention Associated with Clazosentan after Subarachnoid Hemorrhage: A Retrospective Study, Neurol. Res., online ahead of print.","DOI":"10.1080\/01616412.2025.2571954"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/s10143-025-03646-3","article-title":"Clinical Factors Associated with Delayed Ischemic and Non-Ischemic Adverse Events in Clazosentan Therapy after Aneurysmal Subarachnoid Hemorrhage: Early Insights from a Multicenter Prospective Registry","volume":"48","author":"Sugiyama","year":"2025","journal-title":"Neurosurg. Rev."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3171\/2025.5.JNS243007","article-title":"Efficacy of Combined Clazosentan and Cilostazol Therapy for Cerebral Vasospasm after Subarachnoid Hemorrhage: A Retrospective Multicenter Registry Study","volume":"144","author":"Takeuchi","year":"2025","journal-title":"J. Neurosurg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s10143-026-04240-x","article-title":"Safety and Effectiveness of Clazosentan in Patients after Aneurysmal Subarachnoid Haemorrhage: A Second Interim Report of a Post-Marketing Surveillance in Japan","volume":"49","author":"Sakata","year":"2026","journal-title":"Neurosurg. Rev."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Inoue, Y., Katsuki, M., Hidaka, T., Ochiai, J., Kawamoto, Y., Ishii, D., Takizawa, K., Nakatomi, H., Chin, M., and Morioka, M. (2026). Machine Learning-Identified Potential Interaction between Clazosentan and Nicardipine in Patients with Subarachnoid Hemorrhage. J. Clin. Med., 15.","DOI":"10.3390\/jcm15041383"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"411","DOI":"10.2176\/jns-nmc.2025-0439","article-title":"Practical Guide to Clazosentan Administration in Patients with Aneurysmal Subarachnoid Hemorrhage","volume":"66","author":"Suzuki","year":"2026","journal-title":"Neurol. Med. Chir."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Hidaka, T., Ochiai, J., Inoue, Y., Kawamoto, Y., Horie, N., Nishikawa, Y., Mase, M., Morioka, M., Takahashi, J.C., and Shimizu, H. (2025). Japanese Nationwide Questionnaire Survey on the Treatment and Management of Subarachnoid Hemorrhage Due to Ruptured Cerebral Aneurysm. J. Clin. Med., 14.","DOI":"10.3390\/jcm14124107"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1177\/17474930221090347","article-title":"Japan Stroke Society Guideline 2021 for the Treatment of Stroke","volume":"17","author":"Miyamoto","year":"2022","journal-title":"Int. J. Stroke"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1161\/STROKEAHA.110.589275","article-title":"Definition of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies","volume":"41","author":"Vergouwen","year":"2010","journal-title":"Stroke"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1111\/cns.13222","article-title":"Clinical and experimental aspects of aneurysmal subarachnoid hemorrhage","volume":"25","author":"Daou","year":"2019","journal-title":"CNS Neurosci. Ther."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s13054-016-1447-6","article-title":"Management of delayed cerebral ischemia after subarachnoid hemorrhage","volume":"20","author":"Francoeur","year":"2016","journal-title":"Crit. Care"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1161\/STROKEAHA.112.679142","article-title":"Does Prevention of Vasospasm in Subarachnoid Hemorrhage Improve Clinical Outcome? Yes","volume":"44","author":"Macdonald","year":"2013","journal-title":"Stroke"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"105535","DOI":"10.1016\/j.clineuro.2019.105535","article-title":"Clinical Characteristics of Aneurysmal Subarachnoid Hemorrhage in the Elderly over 75; Would Temporal Muscle Be a Potential Prognostic Factor as an Indicator of Sarcopenia?","volume":"186","author":"Katsuki","year":"2019","journal-title":"Clin. Neurol. Neurosurg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e526","DOI":"10.1016\/j.wneu.2020.02.033","article-title":"Temporal Muscle as an Indicator of Sarcopenia Is Independently Associated with Hunt and Kosnik Grade on Admission and the Modified Rankin Scale at 6 Month of Patients with Subarachnoid Hemorrhage Treated by Endovascular Coiling","volume":"137","author":"Katsuki","year":"2020","journal-title":"World Neurosurg."},{"key":"ref_39","first-page":"e15695","article-title":"Easily Created Prediction Model Using Automated Artificial Intelligence Framework (Prediction One, Sony Network Communications Inc., Tokyo, Japan) for Subarachnoid Hemorrhage Outcomes Treated by Coiling and Delayed Cerebral Ischemia","volume":"13","author":"Katsuki","year":"2021","journal-title":"Cureus"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/16\/6424\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T08:42:52Z","timestamp":1787215372000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/15\/16\/6424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":39,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["jcm15166424"],"URL":"https:\/\/doi.org\/10.3390\/jcm15166424","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,19]]}}}