{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T09:24:39Z","timestamp":1787304279666,"version":"build-2736575974"},"reference-count":33,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Pierre Fabre, France"},{"id":[{"id":"https:\/\/ror.org\/04hdhz511","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Actinic keratosis (AK) is the key precursor of invasive cutaneous squamous cell carcinoma (cSCC). Rising incidence, ageing populations, and limited dermatologists\u2019 availability, particularly in rural and underserved regions, underscore the need for more inclusive care pathways. As in other common diseases such as diabetes or hypertension, general practitioners (GPs) could play a pivotal role in improving access, early recognition, and management of AK, provided that systemic barriers are addressed. Methods: This article synthesises current evidence and expert insights from a European multi-country advisory process, focusing on Italy, France, Germany, Spain, Portugal, the Netherlands, and Greece. The advisory board comprised dermatologists selected based on their clinical expertise and national representativeness, and consensus was reached through structured discussion and iterative review of background materials. Results\/Conclusions: The study outlines unmet needs, barriers, and enablers for GPs\u2019 involvement and proposes a structured strategy supported by consensus recommendations. It offers a pragmatic model for improving AK care through stronger collaboration between primary care and dermatology. Greater GPs\u2019 involvement may support earlier recognition, better triage, improved access to care, and more efficient use of specialist services, while ensuring that complex or high-risk lesions remain under dermatologists\u2019 oversight. This may help optimise AK care pathways across Europe.<\/jats:p>","DOI":"10.3390\/jcm15166467","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T08:14:01Z","timestamp":1787300041000},"page":"6467","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of General Practitioners in Actinic Keratosis Management in Europe: A Dermato-Oncologists Initiative"],"prefix":"10.3390","volume":"15","author":[{"given":"Claas","family":"Ulrich","sequence":"first","affiliation":[{"name":"Collegium Medicum GmbH, 10117 Berlin, Germany"},{"name":"Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Institut f\u00fcr Allergieforschung IFA & Fraunhofer Standort Immunologie und Allergologie IA, 10117 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4603-1825","authenticated-orcid":false,"given":"Markus V.","family":"Heppt","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Deutsches Zentrum Immuntherapie (DZI), Uniklinikum Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg (FAU), 91054 Erlangen, Germany"},{"name":"Comprehensive Cancer Center, Erlangen-European Metropolitan Area of Nuremberg (CC ER-EMN), 91054 Erlangen, Germany"},{"name":"Bavarian Cancer Research Center (BZKF), 91054 Erlangen, Germany"},{"name":"Dermpath M\u00fcnchen, Laboratory for Dermatopathology, Oral Pathology and Molecular Pathology, 80335 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1413-8214","authenticated-orcid":false,"given":"Giuseppe","family":"Argenziano","sequence":"additional","affiliation":[{"name":"Dermatology Unit, University of Campania, 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7249-2556","authenticated-orcid":false,"given":"Maria Concetta","family":"Fargnoli","sequence":"additional","affiliation":[{"name":"San Gallicano Dermatological Institute, IRCCS, 00144 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3688-9596","authenticated-orcid":false,"given":"Carla","family":"Ferr\u00e1ndiz-Pulido","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital Universitari Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jouary","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Hospital Francois Mitterrand, 64000 Pau, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7193-0964","authenticated-orcid":false,"given":"Aimilios","family":"Lallas","sequence":"additional","affiliation":[{"name":"First Department of Dermatology and Venereology, School of Medicine, Faculty of Health Sciences, Aristotle University, 54124 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3970-4377","authenticated-orcid":false,"given":"C\u00e9sar","family":"Martins","sequence":"additional","affiliation":[{"name":"Department of Dermatology, ULS M\u00e9dio Tejo, 2350 Torres Novas, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9065-3050","authenticated-orcid":false,"given":"Klara","family":"Mosterd","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Maastricht University Medical Center+, 6202 AZ Maastricht, The Netherlands"},{"name":"GROW Research Institute for Oncology and Reproduction, Maastricht University, 6200 MD Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6500-3507","authenticated-orcid":false,"given":"Philippe","family":"Saiag","sequence":"additional","affiliation":[{"name":"Department of General and Oncologic Dermatology, Ambroise Par\u00e9 Hospital, APHP, & EA 4340 \u201cBiomarkers in Cancerology and OncoHematology\u201d, UVSQ, Universit\u00e9 Paris-Saclay, 92100 Boulogne-Billancourt, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6854-9996","authenticated-orcid":false,"given":"Nathalie","family":"B\u00e9geault","sequence":"additional","affiliation":[{"name":"Medical Dermatology Department, Pierre Fabre M\u00e9dicament, Les Cauquillous, 81506 Lavaur, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8821-6559","authenticated-orcid":false,"given":"Alba","family":"Crespo-Cruz","sequence":"additional","affiliation":[{"name":"Medical Dermatology Department, Pierre Fabre M\u00e9dicament, Les Cauquillous, 81506 Lavaur, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"ref_1","first-page":"675","article-title":"Diagnosis and Therapy of Actinic Keratosis","volume":"22","author":"Thamm","year":"2024","journal-title":"JDDG J. 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