{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T16:44:12Z","timestamp":1787330652946,"version":"build-2736575974"},"reference-count":50,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Chronic low back pain (CLBP) is the leading global cause of years lived with disability, but long-term real-world evidence for non-surgical management remains scarce, particularly in low- and middle-income countries. This study aimed to describe 5-year trajectories of pain, disability, healthcare utilization, patient satisfaction, and surgical conversion among patients with non-specific CLBP initially managed non-surgically at a tertiary spine center in Northwest China. We also compared long-term outcomes between unimodal therapy and multidisciplinary biopsychosocial care and examined baseline demographic, clinical, and psychosocial predictors of treatment success and conversion to surgery. Methods: We conducted a 5-year retrospective cohort study of consecutive patients with non-specific CLBP at a tertiary spine center in Northwest China. Of 485 consecutive patients screened for eligibility, 420 were enrolled and were compared on the basis of unimodal therapy with multidisciplinary biopsychosocial care. Primary outcomes were pain (Numerical Pain Rating Scale, NPRS) and disability (Oswestry Disability Index, ODI), analyzed using linear mixed-effects models; predictors of surgical conversion were identified via multivariable Cox regression. Results: Of the 420 patients, 352 (83.8% retention) completed the 5-year follow-up. Both pain and disability improved substantially during the first 12 months. Thereafter, pain intensity increased slightly (NPRS from 4.8 to 5.4), whereas functional disability continued to improve (ODI from 31.7 to 26.5). Early multidisciplinary care was associated with sustained superior outcomes (adjusted functional disability (ODI) difference: \u22128.2 points at 5 years) and a 42% lower observed risk of surgery (HR = 0.58). The cumulative 5-year surgical rate was 14.2%, with high pain catastrophizing as the strongest independent predictor (HR = 3.10). Conclusions: In patients with non-specific CLBP, non-surgical management yields substantial 12-month gains; function continues to improve through 5 years, while pain shows partial recurrence. Early multidisciplinary biopsychosocial care was associated with more durable outcomes and lower surgical conversion; because treatment was not randomized, these associations warrant confirmation in pragmatic trials and support routine psychosocial screening and stratified care.<\/jats:p>","DOI":"10.3390\/jcm15166497","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T15:51:05Z","timestamp":1787327465000},"page":"6497","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal Non-Surgical Management for Chronic Low Back Pain: A 5-Year Cohort Study from a Tertiary Spine Center in Northwest China"],"prefix":"10.3390","volume":"15","author":[{"given":"Bolong","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University, Xi\u2019an 710054, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University, Xi\u2019an 710054, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University, Xi\u2019an 710054, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baorong","family":"He","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University, Xi\u2019an 710054, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.1016\/S2665-9913(23)00098-X","article-title":"Global, regional, and national burden of low back pain, 1990\u20132020, its attributable risk factors, and projections to 2050: A systematic analysis of the Global Burden of Disease Study 2021","volume":"5","author":"Ferreira","year":"2023","journal-title":"Lancet Rheumatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.5312\/wjo.v15.i12.1200","article-title":"Low back pain in China: Disease burden and bibliometric analysis","volume":"15","author":"Yang","year":"2024","journal-title":"World J. 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