{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T06:16:00Z","timestamp":1788243360069,"version":"build-2803163510"},"reference-count":48,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Suicide-risk assessment during child and adolescent psychiatric hospitalization draws on patient report, clinical history, and professional observation. Whether nocturnal autonomic physiology is concurrently associated with a structured admission-window assessment after accounting for depressive symptoms and self-reported suicidal ideation remains uncertain. Methods: We analyzed 212 hospitalized children and adolescents receiving inpatient care for a major depressive episode. All had a Nurses\u2019 Global Assessment of Suicide Risk (NGASR) rating, self-report measures, covariates, and first admission-night non-contact autonomic data. Principal component analysis was used to derive a nocturnal autonomic dysregulation factor from heart-rate and heart-rate-variability (HRV) summaries. Ordinary least squares regression with HC3 robust standard errors estimated its concurrent association with NGASR after adjustment for age, sex, BMI, Beck Depression Inventory score, and Chinese Beck Scale for Suicide Ideation score. Score-appropriate sensitivity analyses used Poisson, negative-binomial, and predefined NGASR-category models. Results: Higher autonomic dysregulation was associated with higher NGASR after adjustment for depressive symptoms and self-reported suicidal ideation (standardized beta = 0.182, 95% CI 0.067 to 0.297; p = 0.002; q = 0.005), accounting for an additional 3.2 percentage points of explained variance. The association was similar in a robust Poisson model (incidence-rate ratio = 1.059, 95% CI 1.022 to 1.097; p = 0.001) and remained stable after adjustment for subjective sleep quality, AHI, sleep efficiency, and monitoring timing. Separate component models showed larger associations for SDNN and RMSSD than for heart rate or LF\/HF, but did not decompose the composite effect. Conclusions: Admission-window nocturnal autonomic dysregulation showed a modest concurrent association with clinical suicide-risk assessment after adjustment for depressive symptoms and self-reported suicidal ideation. The finding does not establish disclosure-independent assessment, temporal improvement of admission assessment, or prediction of future suicidal behavior.<\/jats:p>","DOI":"10.3390\/jcm15176719","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:45:13Z","timestamp":1788241513000},"page":"6719","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nocturnal Autonomic Dysregulation and Admission-Window Clinical Suicide-Risk Assessment in Hospitalized Children and Adolescents"],"prefix":"10.3390","volume":"15","author":[{"given":"Qiyuan","family":"Cao","sequence":"first","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"Jiaqi","family":"Xu","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"}]},{"given":"Wenjing","family":"Li","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Xuehua","family":"Huang","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Kexin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Jinquan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4026-4083","authenticated-orcid":false,"given":"Lijun","family":"Jiang","sequence":"additional","affiliation":[{"name":"Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1007\/s10964-024-01969-w","article-title":"Risk and Protective Factors of Self-Harm and Suicidality in Adolescents: An Umbrella Review with Meta-Analysis","volume":"53","author":"Richardson","year":"2024","journal-title":"J. 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