{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:09:05Z","timestamp":1789117745545,"version":"build-2803163510"},"reference-count":20,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Body composition may influence functional capacity and long-term outcomes after thoracic organ transplantation. However, direct comparisons of body composition patterns between heart transplant (HTx) and lung transplant (LTx) recipients remain limited. This study compared body composition parameters and their relationship with time since transplantation in HTx and LTx recipients using bioelectrical impedance analysis (BIA). Methods: This cross-sectional study included 79 clinically stable transplant recipients (38 HTx and 41 LTx) with a median time of 9 months after transplantation (range, 1 month\u20139 years). Body composition was assessed using the SECA mBCA 515 analyzer. Absolute fat mass (AFM), relative fat mass (RFM), fat-free mass (FFM), skeletal muscle mass (SMM), phase angle (PA), and extracellular water-to-total body water ratio (ECW\/TBW) were measured. Associations between body composition parameters and time since transplantation were modelled using adjusted generalized additive models with separate smooth functions for HTx and LTx recipients. Results: Positive cross-sectional associations between AFM and time since transplantation were observed during the 3\u20139-month post-transplant interval in both groups (HTx: 0.72 kg\/month, p = 0.042; LTx: 0.83 kg\/month, p = 0.021). In contrast, significant positive associations between SMM and time since transplantation were observed exclusively among LTx recipients during the 1\u20133-month (0.59 kg\/month, p = 0.039) and 3\u20139-month (0.49 kg\/month, p = 0.003) intervals, whereas no significant associations were observed after HTx. In LTx recipients, ECW\/TBW was negatively associated and PA positively associated with time since transplantation during the 3\u20139-month interval. Conclusions: HTx and LTx recipients exhibited different cross-sectional patterns of body composition according to time since transplantation. HTx recipients were characterized by greater adiposity without a significant association between SMM and time since transplantation, whereas LTx recipients showed positive associations between SMM and time since transplantation during the early post-transplant intervals.<\/jats:p>","DOI":"10.3390\/jcm15187034","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T08:17:42Z","timestamp":1789114662000},"page":"7034","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal Patterns of Body Composition After Heart and Lung Transplantation Assessed by Bioelectrical Impedance Analysis"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3496-2238","authenticated-orcid":false,"given":"Micha\u0142","family":"Bohdan","sequence":"first","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"},{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kowalczys","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Radtke-\u0141ysek","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"},{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wioletta","family":"Raczy\u0144ska","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"},{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Fedyczkowska","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"},{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4998-1663","authenticated-orcid":false,"given":"Aleksandra","family":"Gutowska","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Borzyszkowska","sequence":"additional","affiliation":[{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0142awomir","family":"\u017begle\u0144","sequence":"additional","affiliation":[{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"},{"name":"Division of Pulmonology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Grucha\u0142a","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical University of Gda\u0144sk, Smoluchowskiego 17 Str., 80-214 Gdansk, Poland"},{"name":"University Clinical Centre, Smoluchowskiego 17 Str., 80-952 Gdansk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.12968\/hmed.2024.1018","article-title":"Heart Transplantation: Is It Still the Gold Standard?","volume":"86","author":"Kakoudaki","year":"2025","journal-title":"Br. J. Hosp. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/j.healun.2021.07.005","article-title":"Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation","volume":"40","author":"Leard","year":"2021","journal-title":"J. Heart Lung Transplant."},{"key":"ref_3","first-page":"43","article-title":"Lung transplantation\u2014Indications, follow-up care and long-term results","volume":"122","author":"Michel","year":"2025","journal-title":"Dtsch. \u00c4rztebl. Int."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jbspin.2018.08.001","article-title":"Sarcopenia","volume":"86","author":"Tournadre","year":"2019","journal-title":"Jt. Bone Spine"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1097\/TP.0000000000002696","article-title":"Trends, Determinants, and Impact on Survival of Post-Lung Transplant Weight Changes: A Single-center Longitudinal Retrospective Study","volume":"103","author":"Jomphe","year":"2019","journal-title":"Transplantation"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e021346","DOI":"10.1161\/JAHA.121.021346","article-title":"Impact of Obesity on Heart Transplantation Outcomes","volume":"10","author":"Chouairi","year":"2021","journal-title":"J. Am. Heart Assoc."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/j.healun.2025.04.021","article-title":"Impact of obesity on long term post heart transplantation outcomes","volume":"44","author":"Kim","year":"2025","journal-title":"J. Heart Lung Transplant."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e41877","DOI":"10.1097\/MD.0000000000041877","article-title":"Real-world assessment of body composition in patients hospitalized for acute heart failure: A prospective cohort study","volume":"104","author":"Sams","year":"2025","journal-title":"Medicine"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0002-9149(03)00031-6","article-title":"Body composition and prognosis in chronic systolic heart failure: The obesity paradox","volume":"91","author":"Lavie","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/clc.23118","article-title":"Bioelectrical impedance analysis of body composition and survival in patients with heart failure","volume":"42","author":"Thomas","year":"2019","journal-title":"Clin. Cardiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1378\/chest.121.2.401","article-title":"Impact of Body Weight on Long-term Survival After Lung Transplantation","volume":"121","author":"Kanasky","year":"2002","journal-title":"Chest"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.healun.2024.05.010","article-title":"International Society for Heart and Lung Transplantation Guidelines for the Evaluation and Care of Cardiac Transplant Candidates\u20142024","volume":"43","author":"Peled","year":"2024","journal-title":"J. Heart Lung Transplant."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.1016\/j.healun.2020.01.1065","article-title":"Weight Gain Following Heart Transplantation is Associated with Increased Risk of Rejection and Allograft Vasculopathy: An Analysis of the ISHLT Registry","volume":"39","author":"Peled","year":"2020","journal-title":"J. Heart Lung Transplant."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"E136","DOI":"10.1111\/j.1399-0012.2010.01379.x","article-title":"Disturbed energy metabolism after lung and heart transplantation","volume":"25","author":"Forli","year":"2011","journal-title":"Clin. Transplant."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.healun.2022.01.133","article-title":"Body Composition After Cardiac Transplantation via Bioimpedance Spectroscopy","volume":"41","author":"Hasse","year":"2022","journal-title":"J. Heart Lung Transplant."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e14187","DOI":"10.1111\/ctr.14187","article-title":"Weight gain post\u2013heart transplantation is associated with an increased risk for allograft vasculopathy and rejection","volume":"35","author":"Ram","year":"2021","journal-title":"Clin. Transplant."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/00005768-199804000-00003","article-title":"Resistance exercise prevents glucocorticoid-induced myopathy in heart transplant recipients","volume":"30","author":"Braith","year":"1998","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.xjon.2025.07.009","article-title":"Impact of excessive body fat mass on mortality after lung transplantation","volume":"27","author":"Oshima","year":"2025","journal-title":"JTCVS Open"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"911","DOI":"10.3904\/kjim.2016.358","article-title":"Body fluid status assessment by bio-impedance analysis in patients presenting to the emergency department with dyspnea","volume":"33","author":"Park","year":"2018","journal-title":"Korean J. Intern. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.clnesp.2023.04.029","article-title":"Body composition, lipid profile and clinical parameters are predictors of prognosis in patients with heart failure: Two-year follow-up","volume":"56","author":"Avelino","year":"2023","journal-title":"Clin. Nutr. 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