{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:09:43Z","timestamp":1790672983495,"version":"4.1.0"},"reference-count":17,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background: The C-reactive protein\u2013albumin\u2013lymphocyte (CALLY) index integrates systemic inflammation, nutritional status, and immune function. This study evaluated changes in the CALLY index after sleeve gastrectomy and their associations with weight loss and cardiometabolic changes in women. Methods: This retrospective, observational, single-center study included 72 women who underwent sleeve gastrectomy and had complete preoperative and 12-month postoperative data. The CALLY index was calculated preoperatively and at 12 months. \u0394CALLY was defined as the 12-month value minus the preoperative value. Weight-loss outcomes were assessed using total weight loss (TWL) and excess weight loss (EWL). Associations were evaluated using Spearman\u2019s rank correlation analysis and multivariable linear regression. Results: The CALLY index increased from 1.70 [0.87\u20132.56] preoperatively to 6.94 [2.72\u201315.54] at 12 months (p &lt; 0.001). Mean TWL and EWL were 31.43 \u00b1 7.83% and 73.30 \u00b1 20.12%, respectively. \u0394CALLY correlated positively with TWL (r = 0.303, p = 0.010) and EWL (r = 0.312, p = 0.008) and negatively with \u0394BMI (r = \u22120.250, p = 0.035), \u0394fasting insulin (r = \u22120.234, p = 0.046), \u0394HOMA-IR (r = \u22120.243, p = 0.040), and \u0394triglycerides (r = \u22120.254, p = 0.031). After adjustment for age, preoperative BMI, and diabetes mellitus, \u0394CALLY remained positively associated with TWL (B = 0.342, 95% CI 0.172\u20130.513; p &lt; 0.001). Conclusions: The CALLY index increased significantly during the first year after sleeve gastrectomy in women. Changes in the CALLY index were associated with weight loss and changes in selected metabolic parameters. \u0394CALLY may reflect inflammatory and immunonutritional changes accompanying postoperative weight loss.<\/jats:p>","DOI":"10.3390\/jcm15197552","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:12:42Z","timestamp":1790669562000},"page":"7552","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Changes in the CALLY Index After Sleeve Gastrectomy and Their Association with Weight Loss and Metabolic Parameters in Women"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5883-445X","authenticated-orcid":false,"given":"S\u00fcleyman","family":"Ba\u015f","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Health Sciences, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, 34785 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Turkey"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8046-8490","authenticated-orcid":false,"given":"Sangar","family":"Abdullah","sequence":"additional","affiliation":[{"name":"Department of General Surgery, University of Health Sciences, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, 34785 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Bet\u00fcl","family":"Danap\u0131nar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Karab\u00fck University Education and Research Hospital, 78200 Karab\u00fck, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1977-5127","authenticated-orcid":false,"given":"Mustafa Can","family":"\u015eenoymak","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Hitit University, \u00c7orum Erol Ol\u00e7ok Training and Research Hospital, 19040 \u00c7orum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3046-5784","authenticated-orcid":false,"given":"Murat","family":"Yeni\u00e7eri","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Karaman Training and Research Hospital, 70200 Karaman, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3957-3821","authenticated-orcid":false,"given":"Kadem","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of 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