{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:55:39Z","timestamp":1791201339052,"version":"4.2.0"},"reference-count":43,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Med.","JCM"],"abstract":"<jats:p>Background\/Objectives: Lipedema is an adipose tissue disorder associated with body-related burden. This study compared orthorexic eating tendencies between women with and without lipedema and examined associations with body-shape concern and psychological symptoms. Methods: This controlled cross-sectional study included 44 women with lipedema and 44 women without lipedema. Participants completed the D\u00fcsseldorf Orthorexia Scale (DOS), Body Shape Questionnaire (BSQ), and Hospital Anxiety and Depression Scale (HADS). Associated variables were examined using multiple linear regression. Results: Women with lipedema had higher DOS scores than women without lipedema (25.07 \u00b1 6.55 vs. 20.48 \u00b1 5.05; Cohen\u2019s d = 0.79; p &lt; 0.001). BSQ, HADS-Anxiety, and HADS-Depression scores were also higher in the lipedema group (all p \u2264 0.001). DOS and BSQ scores were positively correlated in both groups. In the multivariable model, which included group status, age, BMI, BSQ, HADS-A, and HADS-D scores, BSQ score was independently associated with DOS score (B = 0.067; 95% CI 0.025\u20130.108; p = 0.002), whereas group status and the other covariates were not. The model\u2019s adjusted R2 was 0.234. Conclusions: Women with lipedema exhibited greater orthorexic eating tendencies, body-shape concern, and psychological symptoms than controls. Body-shape concern was independently associated with orthorexic eating tendencies. The group difference in DOS scores is largely explained by the higher BSQ scores accompanying lipedema; this should not be interpreted as indicating that lipedema is unrelated to orthorexic tendencies. These findings support consideration of body image when addressing eating behavior in lipedema care.<\/jats:p>","DOI":"10.3390\/jcm15197678","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:57:46Z","timestamp":1791197866000},"page":"7678","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Orthorexic Eating Tendencies and Body Shape Concern in Women with Lipedema: A Controlled Cross-Sectional Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6314-1981","authenticated-orcid":false,"given":"Muhsin","family":"Doran","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Liv Hospital Vadistanbul, 34475 Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7702-0227","authenticated-orcid":false,"given":"Dilara Ekici","family":"Zincirci","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Istanbul Medipol University, 34230 Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Ece G\u00fcreli","family":"\u015eahan","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Liv Hospital Vadistanbul, 34475 Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,10,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1177\/02683555211015887","article-title":"Standard of care for lipedema in the United States","volume":"36","author":"Herbst","year":"2021","journal-title":"Phlebology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/s41467-025-68232-z","article-title":"Lipedema World Alliance Delphi consensus-based position paper on the definition and management of lipedema: Results from the 2023 Lipedema World Congress in Potsdam","volume":"17","author":"Kruppa","year":"2026","journal-title":"Nat. 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