{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:29:27Z","timestamp":1783632567903,"version":"3.55.0"},"reference-count":44,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T00:00:00Z","timestamp":1453766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Foundation Foltra"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background\u2014To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods\u2014GH was administered (mg\/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days\/week and 0.3 two days\/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results\u2014Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions\u2014This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition.<\/jats:p>","DOI":"10.3390\/jcm5020014","type":"journal-article","created":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T10:00:42Z","timestamp":1453802442000},"page":"14","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation"],"prefix":"10.3390","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4153-2543","authenticated-orcid":false,"given":"Jes\u00fas","family":"Devesa","sequence":"first","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"},{"name":"Department of Physiology, School of Medicine, University of Santiago de Compostela, Santiago de Compostela 15710, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hortensia","family":"Lema","sequence":"additional","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Zas","sequence":"additional","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borja","family":"Mun\u00edn","sequence":"additional","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Taboada","sequence":"additional","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Devesa","sequence":"additional","affiliation":[{"name":"Medical Centre Foltra, Traves\u00eda de Montouto 24, Teo 15886, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2016,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s13167-011-0100-3","article-title":"Pathophysiology of perinatal asphyxia: Can we predict and improve individual outcomes?","volume":"2","author":"Morales","year":"2011","journal-title":"EPMA J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","article-title":"Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy","volume":"86","author":"Kurinczuk","year":"2010","journal-title":"Early Hum. 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