{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:41:08Z","timestamp":1761964868201,"version":"build-2065373602"},"reference-count":10,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2017,4,4]],"date-time":"2017-04-04T00:00:00Z","timestamp":1491264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>We present a case of severe adenoviral pneumonia in a 20-year-old immunocompetent host with persistently high fevers. The patient was needlessly given multiple empiric antibiotics for non-existent bacterial co-infection. This case has important antibiotic stewardship lessons for practitioners in approaching fevers in the ICU.<\/jats:p>","DOI":"10.3390\/jcm6040042","type":"journal-article","created":{"date-parts":[[2017,4,4]],"date-time":"2017-04-04T10:15:12Z","timestamp":1491300912000},"page":"42","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Severe Adenoviral Pneumonia in an Immunocompetent Host with Persistent Fevers Treated with Multiple Empiric Antibiotics for Presumed Bacterial Co-Infection: An Antibiotic Stewardship Perspective on De-Escalation Derailed"],"prefix":"10.3390","volume":"6","author":[{"given":"Burke","family":"Cunha","sequence":"first","affiliation":[{"name":"Infectious Disease Division, Winthrop-University Hospital, 222 Station Plaza North (Suite #432), Mineola, New York, NY 11501, USA"},{"name":"School of Medicine, State University of New York, Stony Brook, New York, NY 11794, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Gian","sequence":"additional","affiliation":[{"name":"Infectious Disease Division, Winthrop-University Hospital, 222 Station Plaza North (Suite #432), Mineola, New York, NY 11501, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Klein","sequence":"additional","affiliation":[{"name":"Infectious Disease Division, Winthrop-University Hospital, 222 Station Plaza North (Suite #432), Mineola, New York, NY 11501, USA"},{"name":"School of Medicine, State University of New York, Stony Brook, New York, NY 11794, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,4,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1378\/chest.08-0888","article-title":"Viral Infection in Adults Hospitalized with Community-Acquired Pneumonia Prevalence, Pathogens, and Presentation","volume":"134","author":"Johnstone","year":"2008","journal-title":"CHEST"},{"key":"ref_2","unstructured":"Cunha, B.A. (2010). Pneumonia Essentials, Jones & Bartlett. [3rd ed.]."},{"key":"ref_3","unstructured":"Lynch, J.P., Fishbein, M., and Echavarria, M.A. (2011). Seminars in Respiratory and Critical Care Medicine, Thieme Medical Publishers."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1136\/thx.2004.030411","article-title":"Comparison between Pathogen Directed Antibiotic Treatment and Empiric Broad Spectrum Antibiotic Treatment in Patients with Community Acquired Pneumonia: A prospective randomized Study","volume":"60","author":"Vlaspolder","year":"2005","journal-title":"Thorax"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.idc.2012.11.008","article-title":"What is the Role of Antimicrobial Stewardship in Improving Outcomes of Patients with CAP?","volume":"27","author":"Nussenblatt","year":"2013","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s001340050925","article-title":"Fever in the Intensive Care Unit","volume":"25","author":"Cunha","year":"1999","journal-title":"Int. Care Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0891-5520(05)70294-4","article-title":"Fever in the Intensive Care Unit","volume":"10","author":"Cunha","year":"1996","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_8","first-page":"361","article-title":"Intensive care, not intensive antibiotics","volume":"23","author":"Cunha","year":"1994","journal-title":"Heart Lung"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0749-0704(05)70378-X","article-title":"Fever in the Critical Care Unit","volume":"14","author":"Cunha","year":"1998","journal-title":"Crit. Care Clin."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0891-5520(05)70295-6","article-title":"Treatment of fever","volume":"10","author":"Klein","year":"1996","journal-title":"Infect. Dis. Clin. N. Am."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/6\/4\/42\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:31:55Z","timestamp":1760207515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/6\/4\/42"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,4]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,4]]}},"alternative-id":["jcm6040042"],"URL":"https:\/\/doi.org\/10.3390\/jcm6040042","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2017,4,4]]}}}