{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:51:08Z","timestamp":1787028668264,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2017,4,8]],"date-time":"2017-04-08T00:00:00Z","timestamp":1491609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Hip arthropathy in haemophilic patients is disabling for hip and other common target joints. Even if bleedings in the hip are not frequent, femoroacetabular alterations may affect the functional ability of patients at a very young age. A haematologic prophylaxis combined with an adequate lifestyle and regular and low-traumatic physical activity are the keys to preventing such arthropathy. In the early stages of arthropathy, anti-inflammatory drugs and physical therapy may be sufficient to limit its progression. In cases of recurrent symptoms, viscosupplementation with hyaluronic acid, and chemical synoviorthesis are useful options. In more advanced stages, hip arthroscopy may be treated by synovectomy or loose body removal. For late stages, total hip arthroplasty (THA) is mandatory. Until a few decades ago, the clinical outcomes after hip arthroplasty were variable, due to the different management of patients and the use of old generation implants and couplings. In the last decade, the introduction of the multidisciplinary management and the use of modern cementless implants with high performing materials and less invasive surgical techniques have dramatically improved the functional results. Nowadays, as is the case for other target joints, the purpose of the management in haemophilia centers is the early detection of any hip alterations\u2014by clinical and ultrasound (US) evaluations of patients in childhood\u2014to reveal any early articular damage and to provide adequate treatment in case of symptoms. The present paper represents an updated review of the several approaches to hip arthropathy in haemophilia.<\/jats:p>","DOI":"10.3390\/jcm6040044","type":"journal-article","created":{"date-parts":[[2017,4,13]],"date-time":"2017-04-13T02:39:17Z","timestamp":1492051157000},"page":"44","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Hip Arthropathy in Haemophilia"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-7940","authenticated-orcid":false,"given":"Christian","family":"Carulli","sequence":"first","affiliation":[{"name":"Orthopaedic Clinic, University of Florence, Florence 50139, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Rosa","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Orthopaedic Clinic, University of Florence, Florence 50139, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Innocenti","sequence":"additional","affiliation":[{"name":"Orthopaedic Clinic, University of Florence, Florence 50139, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,4,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.arth.2015.04.035","article-title":"Total hip arthroplasty in haemophilic patients with modern cementless implants","volume":"30","author":"Carulli","year":"2015","journal-title":"J. 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