{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:06:28Z","timestamp":1780340788312,"version":"3.54.1"},"reference-count":20,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T00:00:00Z","timestamp":1534896000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Evans syndrome is a rare disorder with presentations of autoimmune hemolytic anemia and immune thrombocytopenia, in the absence of any underlying cause. Here, we reported a case with a history of Evans syndrome for seven years. A persistent scrotal ulcer with severe pain occurred for two weeks. He called at our emergency room because of a painful, necrolytic cutaneous ulcer over the scrotal region. A biopsy showed sterile dermal neutrophilia with lymphocytic vasculitis, and pyoderma gangrenosum was impressed. The patient received steroid treatment and recovery after one month.<\/jats:p>","DOI":"10.3390\/jcm7090230","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T03:42:37Z","timestamp":1534909357000},"page":"230","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Scrotal Pyoderma Gangrenosum Associated with Evans Syndrome"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8092-274X","authenticated-orcid":false,"given":"Deng-Ho","family":"Yang","sequence":"first","affiliation":[{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Taichung Armed-Forces General Hospital, Taichung 411, Taiwan"},{"name":"Department of Laboratory, Taichung Armed Forces General Hospital, Taichung 411, Taiwan"},{"name":"Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 406, Taiwan"},{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Yin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jan-Ai General Hospital, Taichung 412, Taiwan"},{"name":"Department of Neurosurgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"},{"name":"College of Nursing, Central Taiwan University of Science and Technology, Taichung 406, Taiwan"},{"name":"Department of Neurosurgery, Taichung Veterans General Hospital, Taichung 407, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,8,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1529-8019.2011.01403.x","article-title":"Diagnosis and treatment of the neutrophilic dermatoses (pyoderma gangrenosum, Sweet\u2019s syndrome)","volume":"24","author":"Dabade","year":"2011","journal-title":"Dermatol. Ther."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2340\/00015555-0221","article-title":"Vegetative pyoderma gangrenosum in Behcet\u2019s disease","volume":"87","author":"Kim","year":"2007","journal-title":"Acta. Derm. Venereol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s40257-018-0356-7","article-title":"Underlying Systemic Diseases in Pyoderma Gangrenosum: A Systematic Review and Meta-Analysis","volume":"19","author":"Kridin","year":"2018","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.bjhh.2015.03.002","article-title":"Experience with Evans syndrome in an academic referral center","volume":"37","year":"2015","journal-title":"Rev. Bras. Hematol. Hemoter."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jbspin.2011.07.004","article-title":"Evans syndrome and systemic lupus erythematosus: Clinical presentation and outcome","volume":"79","author":"Costallat","year":"2012","journal-title":"Joint Bone Spine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/MPH.0000000000000880","article-title":"Evans Syndrome as First Manifestation of Primary Immunodeficiency in Clinical Practice","volume":"39","author":"Giner","year":"2017","journal-title":"J. Pediatr. Hematol. Oncol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/MPH.0000000000000550","article-title":"Evans Syndrome Secondary to Common Variable Immune Deficiency","volume":"38","author":"Antoon","year":"2016","journal-title":"J. Pediatr. Hematol. 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Haematol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/7\/9\/230\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:20:15Z","timestamp":1760196015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/7\/9\/230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,22]]},"references-count":20,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2018,9]]}},"alternative-id":["jcm7090230"],"URL":"https:\/\/doi.org\/10.3390\/jcm7090230","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,22]]}}}