{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:16:02Z","timestamp":1768554962356,"version":"3.49.0"},"reference-count":34,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:00:00Z","timestamp":1542931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Multilevel anterior cervical decompression and fixation of four and more levels is a common surgical procedure used for several diseases. Methods: We reviewed the radiological and clinical outcomes after anterior cervical discectomy or corpectomy and fixation of four and more levels in 85 patients (55 men and 30 women) with an average age of 59.6 years. Surgical indication was multilevel cervical degenerative myelopathy and radiculopathy in 72 (85%) patients, multilevel cervical spondylodiscitis in four (5%), complex traumatic cervical fractures in four (5%), metastatic cervical spine tumor in two (2%), and ossification of the posterior longitudinal ligament in three (3%) patients. Results: There were no severe intraoperative complications such as spinal cord or vertebral artery injury or dissection. Seventy-three patients had four, 10 patients had five, and two patients had six anterior cervical level fixations. The visual analog scale (VAS) and Japanese Orthopedic Association (mJOA) scale scores improved (6.9 to 1.3 (p &lt; 0.001) and 13.9 to 16.5 (p &lt; 0.001), respectively). The Cobb angle increased from 5.7\u00b0 to 17.6\u00b0 postoperatively (p &lt; 0.001). Secondary posterior fixation was necessary in three cases due to pseudarthrosis. Conclusion: The anterior approach appears to be optimal for ventral compressive pathology and lordosis restoration to the cervical spine. Limitations of multiple level decompression and fixation included increasing pseudoarthrosis rates, especially after corpectomy, and increasing fused level numbers.<\/jats:p>","DOI":"10.3390\/jcm7120469","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T03:41:31Z","timestamp":1542944491000},"page":"469","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Radiological and Clinical Outcome after Multilevel Anterior Cervical Discectomy and\/or Corpectomy and Fixation"],"prefix":"10.3390","volume":"7","author":[{"given":"Paul","family":"Oni","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Klinikum Dortmund, 44145 Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Schulthei\u00df","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum Dortmund, 44145 Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai-Michael","family":"Scheufler","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum Dortmund, 44145 Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakob","family":"Roberg","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum Dortmund, 44145 Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Harati","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum Dortmund, 44145 Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,11,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.2106\/00004623-195840030-00009","article-title":"The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion","volume":"40","author":"Smith","year":"1958","journal-title":"J. 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