{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:25:46Z","timestamp":1785324346793,"version":"3.55.0"},"reference-count":39,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T00:00:00Z","timestamp":1547596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST107-2221-E-038-009; MOST106-2314-B-038-036-MY3; MOST106-2221-E-038-003"],"award-info":[{"award-number":["MOST107-2221-E-038-009; MOST106-2314-B-038-036-MY3; MOST106-2221-E-038-003"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The impact of diabetes on perioperative outcomes remains incompletely understood. Our purpose is to evaluate post-operative complications and mortality in patients with diabetes. Using the institutional and clinical databases of three university hospitals from 2009\u20132015, we conducted a matched study of 16,539 diabetes patients, aged &gt;20 years, who underwent major surgery. Using a propensity score matching procedure, 16,539 surgical patients without diabetes who underwent surgery were also selected. Logistic regressions were used to calculate the odds ratios (ORs) with 95% confidence intervals (CIs) for post-operative complications and in-hospital mortality associated with diabetes. Patients with diabetes had a higher risk of postoperative septicemia (OR 1.33, 95% CI 1.01\u20131.74), necrotizing fasciitis (OR 3.98, 95% CI 1.12\u201314.2), cellulitis (OR 2.10, 95% CI 1.46\u20133.03), acute pyelonephritis (OR 1.86, 95% CI 1.01\u20133.41), infectious arthritis (OR 3.89, 95% CI 1.19\u201312.7), and in-hospital mortality (OR 1.51, 95% CI 1.07\u20132.13) compared to people without diabetes. Previous admission for diabetes (OR 2.33, 95% CI 1.85\u20132.93), HbA1c &gt;8% (OR 1.96, 95% CI 1.64\u20132.33) and fasting glucose &gt;180 mg\/dL (OR 1.90, 95% CI 1.68\u20132.16) were predictors for post-operative adverse events. Diabetes patients who underwent surgery had higher risks of infectious complications and in-hospital mortality compared with patients without diabetes who underwent similar major surgeries.<\/jats:p>","DOI":"10.3390\/jcm8010100","type":"journal-article","created":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T03:02:03Z","timestamp":1547694123000},"page":"100","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Adverse Outcomes after Major Surgeries in Patients with Diabetes: A Multicenter Matched Study"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6964-3862","authenticated-orcid":false,"given":"Chao-Shun","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuen-Chau","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Wen","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7354-2095","authenticated-orcid":false,"given":"Chih-Chung","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Chieh","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Surgery, China Medical University Hospital, Taichung 404, Taiwan"},{"name":"Department of Surgery, University of Illinois, Chicago, IL 60637, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Cheng","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8945-3513","authenticated-orcid":false,"given":"Ming-Tsang","family":"Chuang","sequence":"additional","affiliation":[{"name":"Office of Information Technology, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7011-3754","authenticated-orcid":false,"given":"Tzu-Hao","family":"Chang","sequence":"additional","affiliation":[{"name":"Office of Information Technology, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta-Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6694-0730","authenticated-orcid":false,"given":"Chien-Chang","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan"},{"name":"Department of Anesthesiology, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei 110, Taiwan"},{"name":"School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan"},{"name":"Department of Anesthesiology, Shuan Ho Hospital, Taipei Medical University, New Taipei City 235, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,1,16]]},"reference":[{"key":"ref_1","unstructured":"NCD Risk Factor Collaboration (2016). 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