{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:17:19Z","timestamp":1768587439881,"version":"3.49.0"},"reference-count":31,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T00:00:00Z","timestamp":1559952000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002649","name":"Yeungnam University","doi-asserted-by":"publisher","award":["2018"],"award-info":[{"award-number":["2018"]}],"id":[{"id":"10.13039\/501100002649","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>In the diagnosis of lung lesions, computed tomography (CT)-guided percutaneous transthoracic needle biopsy (PTNB) has a high diagnostic yield and a low complication rate. The procedure is usually performed by interventional radiologists, but the diagnostic yield and safety of CT-guided PTNB when performed by pulmonologists have not been evaluated. A retrospective study of 239 patients who underwent CT-guided PTNB at Yeungnam University Hospital between March 2017 and April 2018 was conducted. A pulmonologist performed the procedure using a co-axial technique with a 20-gauge needle. Then diagnostic yield and safety were assessed. The overall sensitivity, specificity, positive predictive value, and negative predictive value for the diagnosis of malignancy were 96.1% (171\/178), 100% (46\/46), 100% (171\/171), and 86.8% (46\/53), respectively. The diagnostic accuracy was 96.9% (217\/224) and the overall complication rate was 33.1% (82\/248). Pneumothorax, hemoptysis, and hemothorax occurred in 27.0% (67\/248), 5.2% (13\/248), and 0.8% (2\/248) of the patients, respectively. Univariate analyses revealed that pneumothorax requiring chest tube insertion was a significant risk factor (odds ratio, 25.0; p &lt; 0.001) for diagnostic failure. CT-guided PTNB is a safe procedure with a high diagnostic accuracy, even when performed by an inexperienced pulmonologist. The results were similar to those achieved by interventional radiologists as reported in previously published studies.<\/jats:p>","DOI":"10.3390\/jcm8060821","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T03:16:51Z","timestamp":1560136611000},"page":"821","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Initial Experience in CT-Guided Percutaneous Transthoracic Needle Biopsy of Lung Lesions Performed by a Pulmonologist"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7104-8325","authenticated-orcid":false,"given":"June Hong","family":"Ahn","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Yeungnam University Medical Center, College of Medicine, Yeungnam University, Daegu 42415, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Geol","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yeungnam University Medical Center, College of Medicine, Yeungnam University, Daegu 42415, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1378\/chest.09-0370","article-title":"CT fluoroscopy-guided biopsy of 1000 pulmonary lesions performed with 20-gauge coaxial cutting needles: Diagnostic yield and risk factors for diagnostic failure","volume":"136","author":"Hiraki","year":"2009","journal-title":"Chest"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1148\/radiol.13131265","article-title":"C-arm cone-beam CT-guided percutaneous transthoracic needle biopsy of lung nodules: Clinical experience in 1108 patients","volume":"271","author":"Lee","year":"2014","journal-title":"Radiology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.2214\/ajr.180.6.1801665","article-title":"CT-guided transthoracic needle aspiration biopsy of small (\u226420 mm) solitary pulmonary nodules","volume":"180","author":"Ohno","year":"2003","journal-title":"Am. 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