{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T22:17:40Z","timestamp":1769206660473,"version":"3.49.0"},"reference-count":72,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Spanish Ministry of Education and Vocational Training","award":["FPU16\/01093 and FPU14\/04172"],"award-info":[{"award-number":["FPU16\/01093 and FPU14\/04172"]}]},{"DOI":"10.13039\/501100006393","name":"University of Granada","doi-asserted-by":"publisher","award":["Plan Propio de Investigaci\u00f3n 2019-Programa Contratos-Puentes"],"award-info":[{"award-number":["Plan Propio de Investigaci\u00f3n 2019-Programa Contratos-Puentes"]}],"id":[{"id":"10.13039\/501100006393","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006393","name":"University of Granada","doi-asserted-by":"publisher","award":["Plan Propio 394 de Investigaci\u00f3n 2016-Excellence actions: Unit of Excellence on Exercise and Health (UCEES)"],"award-info":[{"award-number":["Plan Propio 394 de Investigaci\u00f3n 2016-Excellence actions: Unit of Excellence on Exercise and Health (UCEES)"]}],"id":[{"id":"10.13039\/501100006393","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Junta de Andaluc\u00eda, Consejer\u00eda de Conocimiento, Investigaci\u00f3n y Universidades","award":["European Regional Development Funds, SOMM17\/6107\/UGR)"],"award-info":[{"award-number":["European Regional Development Funds, SOMM17\/6107\/UGR)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The prevalence and treatment response of depression and anxiety symptoms in obstructive sleep apnoea (OSA), although widely addressed in research and clinical settings, still remain unclear due to overlapping symptoms. The ADIPOSA study sought to elucidate the presence of non-overlapping symptoms of depression and anxiety in patients with moderate to severe OSA before and after continuous positive airway pressure (CPAP) treatment. Forty-eight adults aged 18\u201380 (68.75% men) with moderate to severe OSA were enrolled in this twelve-week longitudinal single-arm trial and completed a full-night ambulatory sleep diagnostic test and an assessment of cognitive-affective depression and anxiety symptoms using the Beck-Depression Inventory-Fast Screen (BDI-FS), the State-Trait Depression Inventory (IDER) and the State-Trait Anxiety Inventory (STAI). We found no cognitive-affective depression or anxiety symptoms of clinical relevance at baseline. The amelioration of depression and anxiety symptoms after CPAP use was only statistically significant when considering anxiety-trait (p &lt; 0.01; d = 0.296) and euthymia (p &lt; 0.05; d = 0.402), the distinctive component of depression. Although dysthymia or high negative affect remained unchanged, CPAP may be effective at reducing the lack of positive affect, a well-established health-protective factor. However, not until depression and anxiety disorders related to OSA are accurately measured in clinical and research settings will it be possible to obtain robust conclusions on the occurrence and amelioration of these symptoms after treatment.<\/jats:p>","DOI":"10.3390\/jcm8122099","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T10:50:45Z","timestamp":1575283845000},"page":"2099","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Anxiety and Depression in Patients with Obstructive Sleep Apnoea before and after Continuous Positive Airway Pressure: The ADIPOSA Study"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3879-6468","authenticated-orcid":false,"given":"Almudena","family":"Carneiro-Barrera","sequence":"first","affiliation":[{"name":"Sleep and Health Promotion Laboratory, Mind, Brain and Behaviour Research Centre (CIMCYC), University of Granada, 18011 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7207-9016","authenticated-orcid":false,"given":"Francisco J.","family":"Amaro-Gahete","sequence":"additional","affiliation":[{"name":"EFFECTS-262 Research group, Department of Medical Physiology, School of Medicine, University of Granada, 18071 Granada, Spain"},{"name":"PROmoting FITness and Health through physical activity research group (PROFITH), Sport and Health University Research Institute (iMUDS), Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germ\u00e1n","family":"S\u00e1ez-Roca","sequence":"additional","affiliation":[{"name":"Unidad de Trastornos Respiratorios del Sue\u00f1o, Servicio de Neumolog\u00eda, \u201cVirgen de las Nieves\u201d University Hospital, 18014 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Mart\u00edn-Carrasco","sequence":"additional","affiliation":[{"name":"Unidad de Trastornos Respiratorios del Sue\u00f1o, Servicio de Neumolog\u00eda, \u201cVirgen de las Nieves\u201d University Hospital, 18014 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7548-7138","authenticated-orcid":false,"given":"Jonatan","family":"R. Ruiz","sequence":"additional","affiliation":[{"name":"PROmoting FITness and Health through physical activity research group (PROFITH), Sport and Health University Research Institute (iMUDS), Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gualberto","family":"Buela-Casal","sequence":"additional","affiliation":[{"name":"Sleep and Health Promotion Laboratory, Mind, Brain and Behaviour Research Centre (CIMCYC), University of Granada, 18011 Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.smrv.2016.07.002","article-title":"Prevalence of obstructive sleep apnea in the general population: A systematic review","volume":"34","author":"Senaratna","year":"2017","journal-title":"Sleep Med. 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