{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:18:38Z","timestamp":1792268318971,"version":"4.4.0"},"reference-count":11,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T00:00:00Z","timestamp":1580169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Vaginal mesh erosion is a devastating complication after pelvic floor mesh surgery and it can be treated conservatively or with surgical revision. However, the management options following a failed primary revision or complex vaginal erosions are very limited. The aim of this study is to describe a novel treatment using an amniotic membrane as an inlay graft for such patients. Eight patients who failed conservative or primary surgical revision were enrolled. The complex erosions included vaginal agglutination, multiple vaginal erosions, recurrent erosions, and mesh cutting through the urethra. We used an amniotic membrane as a graft to cover the vaginal defect after partial excision of the mesh erosion and we describe the technique in this study. There were no intraoperative complications and none of the patients reported any further symptoms at a mean of 27 months follow-up. Only one patient had recurrent erosion, however, the erosion size was narrower and was subsequently successfully repaired. No further vaginal mesh erosions were noted in the other patients who all had good functional recovery. The use of an amniotic graft can be an economic and alternative method in the management of complex vaginal mesh erosions.<\/jats:p>","DOI":"10.3390\/jcm9020356","type":"journal-article","created":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T09:37:09Z","timestamp":1580204229000},"page":"356","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Amniotic Membrane Graft in the Management of Complex Vaginal Mesh Erosion"],"prefix":"10.3390","volume":"9","author":[{"given":"Hui-Hsuan","family":"Lau","sequence":"first","affiliation":[{"name":"Department of Medicine, Mackay Medical College, New Taipei 252, Taiwan"},{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Mackay Medicine, Nursing and Management College, New Taipei 251, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Hsinchu Mackay Memorial Hospital, Hsinchu 300, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan-Bin","family":"Jou","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mackay Medical College, New Taipei 252, Taiwan"},{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Mackay Medicine, Nursing and Management College, New Taipei 251, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mackay Medical College, New Taipei 252, Taiwan"},{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Mackay Medicine, Nursing and Management College, New Taipei 251, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Hsien","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mackay Medical College, New Taipei 252, Taiwan"},{"name":"Division of Urogynecology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Mackay Medicine, Nursing and Management College, New Taipei 251, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Hsinchu Mackay Memorial Hospital, Hsinchu 300, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Maher, C., Feiner, B., Baessler, K., and Schmid, C. (2013). Surgical management of pelvic organ prolapse in women. Cochrane Database Syst Rev., CD004014.","DOI":"10.1002\/14651858.CD004014.pub5"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.eururo.2017.04.026","article-title":"Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence","volume":"72","author":"Fusco","year":"2017","journal-title":"Eur Urol."},{"key":"ref_3","unstructured":"U.S. Food and Drug Administration (2008). FDA Public Health Notification: Serious Complications Associated with Transvaginal Placement of Surgical Mesh in Repair of Pelvic Organ Prolapse and Stress Urinary Incontinence, U.S. Food and Drug Administration."},{"key":"ref_4","unstructured":"U.S. Food and Drug Administration (2011). Update on Serious Complications Associated with Transvaginal Placement of Surgical Mesh for Pelvic Organ Prolapse: FDA Safety Communication, U.S. Food and Drug Administration."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.tjog.2016.02.021","article-title":"Risk factors and management of vaginal mesh erosion after pelvic organ prolapse surgery","volume":"56","author":"Cheng","year":"2017","journal-title":"Taiwan J Obstet Gynecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jmig.2012.10.007","article-title":"Martius graft for management of exposed vaginal prolapse mesh","volume":"20","year":"2013","journal-title":"J Minim Invasive Gynecol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/AOG.0b013e31819eca9b","article-title":"Martius graft for the management of tension-free vaginal tape vaginal erosion","volume":"114","year":"2009","journal-title":"Obstet. Gynecol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/iwj.12976","article-title":"A confirmatory study on the efficacy of dehydrated human amnion\/chorion membrane dHACM allograft in the management of diabetic foot ulcers: A prospective, multicentre, randomised, controlled study of 110 patients from 14 wound clinics","volume":"16","author":"Tettelbach","year":"2019","journal-title":"Int Wound J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/ICO.0000000000001866","article-title":"Effectiveness of Cryopreserved Amniotic Membrane Transplantation in Corneal Ulceration: A Meta-Analysis","volume":"38","author":"Liu","year":"2019","journal-title":"Cornea"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"NICE Guidance (2019). Urinary incontinence and pelvic organ prolapse in women: management: \u00a9 NICE (2019) Urinary incontinence and pelvic organ prolapse in women: Management. BJU Int., 123, 777\u2013803.","DOI":"10.1111\/bju.14763"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5500\/wjt.v4.i2.111","article-title":"Human amniotic membrane transplantation: Different modalities of its use in ophthalmology","volume":"4","author":"Malhotra","year":"2014","journal-title":"World J Transplant."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/2\/356\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:20:46Z","timestamp":1760361646000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/2\/356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,28]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2]]}},"alternative-id":["jcm9020356"],"URL":"https:\/\/doi.org\/10.3390\/jcm9020356","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,28]]}}}