{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:46:24Z","timestamp":1760237184882,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: We report outcome data of patients treated with coronary bioresorbable scaffolds up to 5 years and investigate predictors of adverse events. Methods: Consecutive patients treated with at least one coronary bioresorbable scaffold (BRS, Abbott Vascular, Santa Clara, USA) between May 2012 and May 2014 in our center were enrolled. Clinical\/procedural characteristics and outcome data at 1868 (1641\u20132024) days were collected. The incidence of scaffold thrombosis (ScT), restenosis (ScR), and target lesion failure (TLF) and their predictors were investigated using Kaplan\u2013Meier and Cox regression analysis. Results: 512 consecutive patients and 598 lesions were included in the database. A total of 30 ScT, 42 ScR, and 92 TLF were reported. The rate of ScT was 3.6% in the first year, 2.2% in the second\u2013third year, and 0.6% in the fourth\u2013fifth year after implantation. The corresponding rates of ScR were 2.5%, 5.7%, and 1.1%. The corresponding incidence of TLF was 8.8%, 8.0%, 3.8%. Procedural parameters (vessel size, scaffold footprint) and the technique used at implantation (including predilation, parameters of sizing, and postdilation) were predictors of ScT and TLF in the first three years after implantation. In contrast, only diabetes was predictive of events between 4\u20135 years (HR 6.21(1.99\u201319.40), p = 0.002). Conclusions: After device resorption, the incidence of very late adverse events in lesions\/patients implanted with a BRS decreases. Procedural and device-related parameters are not predictors of events anymore.<\/jats:p>","DOI":"10.3390\/jcm9030847","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T11:42:11Z","timestamp":1584704531000},"page":"847","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Five Years Outcomes and Predictors of Events in a Single-Center Cohort of Patients Treated with Bioresorbable Coronary Vascular Scaffolds"],"prefix":"10.3390","volume":"9","author":[{"given":"Remzi","family":"Anadol","sequence":"first","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"M\u00fchlenhaus","sequence":"additional","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann-Kristin","family":"Trieb","sequence":"additional","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9166-3031","authenticated-orcid":false,"given":"Alberto","family":"Polimeni","sequence":"additional","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"},{"name":"Division of Cardiology, Department of Medical and Surgical Sciences, \"Magna Graecia\" University, 88100 Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5503-4150","authenticated-orcid":false,"given":"Thomas","family":"M\u00fcnzel","sequence":"additional","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2917-6707","authenticated-orcid":false,"given":"Tommaso","family":"Gori","sequence":"additional","affiliation":[{"name":"Kardiologie I, Zentrum f\u00fcr Kardiologie, University Medical Center Mainz and Deutsches Zentrum f\u00fcr Herz und Kreislauf Forschung, Standort Rhein-Main 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.jacc.2011.05.050","article-title":"Evaluation of the second generation of a bioresorbable everolimus-eluting vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes","volume":"58","author":"Serruys","year":"2011","journal-title":"J. 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