{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:18:43Z","timestamp":1790705923563,"version":"4.1.0"},"reference-count":86,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T00:00:00Z","timestamp":1585094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["EH 367\/5-1, SFB 940\/1, SM 80\/7-2"],"award-info":[{"award-number":["EH 367\/5-1, SFB 940\/1, SM 80\/7-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The capacity of patients with anorexia nervosa (AN) to resist food-based rewards is often assumed to reflect excessive self-control. Previous cross-sectional functional magnetic resonance imaging (fMRI) studies utilizing the delay discounting (DD) paradigm, an index of impulsivity and self-control, suggested altered neural efficiency of decision-making in acutely underweight patients (acAN) and a relative normalization in long-term, weight-recovered individuals with a history of AN (recAN). The current longitudinal study tested for changes in functional magnetic resonance imaging (fMRI) activation during DD associated with intensive weight restoration treatment. A predominately adolescent cohort of 22 female acAN patients (mean age\u201415.5 years) performed an established DD paradigm during fMRI at the beginning of hospitalization and again after partial weight restoration (\u226512% body mass index (BMI) increase). Analyses investigated longitudinal changes in both reward valuation and executive decision-making processes. Additional exploratory analyses included comparisons with data acquired in aged-matched healthy controls (HC) as well as probes of functional connectivity between empirically identified nodes of the \u201ctask-positive\u201d frontoparietal control network (FPN) and \u201ctask-negative\u201d default-mode network (DMN). While treatment was not associated with changes in behavioral DD parameters or activation, specific to reward processing, deactivation of the DMN during decision-making was significantly less pronounced following partial weight restoration. Strengthened DMN activation during DD might reflect a relative relaxation of cognitive overcontrol or improved self-referential, decision-making. Together, our findings present further evidence that aberrant decision-making in AN might be remediable by treatment and, therefore, might constitute an acute effect rather than a core trait variable of the disorder.<\/jats:p>","DOI":"10.3390\/jcm9040900","type":"journal-article","created":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T13:39:34Z","timestamp":1585834774000},"page":"900","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Strengthened Default Mode Network Activation During Delay Discounting in Adolescents with Anorexia Nervosa After Partial Weight Restoration: A Longitudinal fMRI Study"],"prefix":"10.3390","volume":"9","author":[{"given":"Arne","family":"Doose","sequence":"first","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2864-5578","authenticated-orcid":false,"given":"Joseph A.","family":"King","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Bernardoni","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2076-5329","authenticated-orcid":false,"given":"Daniel","family":"Geisler","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger","family":"Hellerhoff","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"},{"name":"Translational Developmental Neuroscience Section, Eating Disorder Research and Treatment Center, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Weinert","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veit","family":"Roessner","sequence":"additional","affiliation":[{"name":"Translational Developmental Neuroscience Section, Eating Disorder Research and Treatment Center, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5398-5569","authenticated-orcid":false,"given":"Michael N.","family":"Smolka","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Neuroimaging Center, Technische Universit\u00e4t Dresden, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Division of Psychological and Social Medicine and Developmental Neuroscience, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"},{"name":"Translational Developmental Neuroscience Section, Eating Disorder Research and Treatment Center, Faculty of Medicine, Dresden University of Technology, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM-5\u00ae), American Psychiatric Association.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S2215-0366(15)00356-9","article-title":"Anorexia nervosa: Aetiology, assessment, and treatment","volume":"2","author":"Zipfel","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"15075","DOI":"10.1038\/nrdp.2015.75","article-title":"Anorexia nervosa","volume":"1","author":"Treasure","year":"2015","journal-title":"Nat. Rev. Dis. Prim."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrn2682","article-title":"New insights into symptoms and neurocircuit function of anorexia nervosa","volume":"10","author":"Kaye","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3389\/fnbeh.2014.00410","article-title":"Are Extremes of Consumption in Eating Disorders Related to an Altered Balance between Reward and Inhibition?","volume":"8","author":"Wierenga","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"ref_6","unstructured":"Bruch, H. (2001). The Golden Cage: The Enigma of Anorexia Nervosa, Harvard University Press."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.neubiorev.2015.11.017","article-title":"Reward-related decision making in eating and weight disorders: A systematic review and meta-analysis of the evidence from neuropsychological studies","volume":"61","author":"Wu","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neubiorev.2015.02.012","article-title":"A reward-centred model of anorexia nervosa: A focussed narrative review of the neurological and psychophysiological literature","volume":"52","author":"Campbell","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.biopsych.2017.11.024","article-title":"Exaggerated Control Demands Over Reward-Related Behavior in Anorexia Nervosa","volume":"83","author":"Kroemer","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.psc.2018.10.008","article-title":"Cognitive Neuroscience of Eating Disorders","volume":"42","author":"Steinglass","year":"2019","journal-title":"Psychiatr. Clin. North Am."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40337-016-0106-2","article-title":"Neurobiological model of the persistence of anorexia nervosa","volume":"4","author":"Steinglass","year":"2016","journal-title":"J. Eat. Disord."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.neubiorev.2016.09.024","article-title":"A systematic review of temporal discounting in eating disorders and obesity: Behavioural and neuroimaging findings","volume":"71","author":"McClelland","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1017\/S0033291718001770","article-title":"Can delay discounting deliver on the promise of RDoC?","volume":"49","author":"Lempert","year":"2019","journal-title":"Psychol. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.tics.2007.08.011","article-title":"Intertemporal choice\u2013toward an integrative framework","volume":"11","author":"Berns","year":"2007","journal-title":"Trends Cogn. Sci."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Madden, G.J., and Bickel, W.K. (2010). Impulsivity: The Behavioral and Neurological Science of Discounting, American Psychological Association.","DOI":"10.1037\/12069-000"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.biopsych.2014.12.016","article-title":"On Weight and Waiting: Delay Discounting in Anorexia Nervosa Pretreatment and Posttreatment","volume":"78","author":"Decker","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1017\/S1355617712000446","article-title":"Increased Capacity to Delay Reward in Anorexia Nervosa","volume":"18","author":"Steinglass","year":"2012","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/erv.2543","article-title":"Delay discounting of reward and impulsivity in eating disorders: From anorexia nervosa to binge eating disorder","volume":"25","author":"Steward","year":"2017","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1001\/jamapsychiatry.2019.2102","article-title":"Delay Discounting as a Transdiagnostic Process in Psychiatric Disorders: A Meta-analysis","volume":"76","author":"Amlung","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1017\/S0033291714002311","article-title":"Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa","volume":"45","author":"Ritschel","year":"2015","journal-title":"Psychol. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/erv.2513","article-title":"Temporal discounting and the tendency to delay gratification across the eating disorder spectrum","volume":"25","author":"Bartholdy","year":"2017","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.biopsych.2014.09.024","article-title":"Hunger does not motivate reward in women remitted from anorexia nervosa","volume":"77","author":"Wierenga","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"ref_23","first-page":"180252","article-title":"Intact value-based decision-making during intertemporal choice in women with remitted anorexia nervosa? An fMRI study","volume":"44","author":"King","year":"2019","journal-title":"J. Psychiatry Neurosci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1001\/jamapsychiatry.2019.4121","article-title":"The Elusive Nature of Delay Discounting as a Transdiagnostic Process in Psychiatric Disorders\u2014The Devil Is in the Detail","volume":"77","author":"King","year":"2020","journal-title":"JAMA Psychiatry"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/wcs.1246","article-title":"The neural correlates of temporal reward discounting","volume":"4","author":"Scheres","year":"2013","journal-title":"Wiley Interdiscip. Rev. Cogn. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1038\/nn2007","article-title":"The neural correlates of subjective value during intertemporal choice","volume":"10","author":"Kable","year":"2007","journal-title":"Nat. Neurosci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1126\/science.1100907","article-title":"Separate Neural Systems Value Immediate and Delayed Monetary Rewards","volume":"306","author":"McClure","year":"2004","journal-title":"Science"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"520","DOI":"10.3389\/fpsyg.2016.00849","article-title":"Is Anorexia Nervosa a Disorder of the Self? A Psychological Approach","volume":"7","author":"Amianto","year":"2016","journal-title":"Front. Psychol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/erv.726","article-title":"Identity impairment and the eating disorders: Content and organization of the self-concept in women with anorexia nervosa and bulimia nervosa","volume":"15","author":"Stein","year":"2007","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3389\/fpsyg.2019.00219","article-title":"Anorexia Nervosa and a Lost Emotional Self: A Psychological Formulation of the Development, Maintenance, and Treatment of Anorexia Nervosa","volume":"10","author":"Oldershaw","year":"2019","journal-title":"Front. Psychol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1176\/ajp.139.12.1531","article-title":"Anorexia Nervosa: Therapy and theory","volume":"139","author":"Bruch","year":"1982","journal-title":"AJP"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1749-6632.2011.06201.x","article-title":"Future self-continuity: How conceptions of the future self transform intertemporal choice: Hershfield","volume":"1235","author":"Hershfield","year":"2011","journal-title":"Ann. New York Acad. Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","article-title":"The brain\u2019s default mode network","volume":"38","author":"Raichle","year":"2015","journal-title":"Annu. Rev. Neurosci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.neuroimage.2017.08.045","article-title":"Neuroanatomical foundations of delayed reward discounting decision making","volume":"161","author":"Owens","year":"2017","journal-title":"NeuroImage"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1037\/a0018046","article-title":"Functional neuroimaging of intertemporal choice models: A review","volume":"3","author":"Carter","year":"2010","journal-title":"J. Neurosci. Psychol. Econ."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.tem.2019.08.004","article-title":"A Metabolic Perspective on Reward Abnormalities in Anorexia Nervosa","volume":"30","author":"Duriez","year":"2019","journal-title":"Trends Endocrinol. Metab."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/nrendo.2016.175","article-title":"The endocrine manifestations of anorexia nervosa: Mechanisms and management","volume":"13","author":"Schorr","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/eat.22481","article-title":"Cardiovascular complications of anorexia nervosa: A systematic review","volume":"49","author":"Sachs","year":"2016","journal-title":"Int. J. Eat. Disord."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s11920-013-0396-x","article-title":"Altered Brain Reward Circuits in Eating Disorders: Chicken or Egg?","volume":"15","author":"Frank","year":"2013","journal-title":"Curr. Psychiatry Rep."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.jaac.2016.08.005","article-title":"Altered Neural Efficiency of Decision Making During Temporal Reward Discounting in Anorexia Nervosa","volume":"55","author":"King","year":"2016","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_41","unstructured":"Fichter, M.M., and Quadflieg, N. (1999). Strukturiertes Inventar f\u00fcr Anorektische und Bulimische E\u00dfst\u00f6rungen: (SIAB); Fragebogen (SIAB-S) und Interview (SIAB-EX) nach DSM-IV und ICD-10; Handanweisung, Hogrefe Verlag f\u00fcr Psychologie."},{"key":"ref_42","unstructured":"Paul, T., and Thiel, A. (2005). Eating Disorder Inventory-2: EDI-2, Hogrefe. deutsche Version."},{"key":"ref_43","unstructured":"Hautzinger, M., Keller, F., and K\u00fchner, C. (2009). BDI-II. Beck Depressions-Inventar Revision, Pearson Assessment and Information GmbH."},{"key":"ref_44","unstructured":"Petermann, F., and Petermann, M. (2010). HAWIK-IV, Hogrefe Verlag."},{"key":"ref_45","unstructured":"Von Aster, M., Neubauer, A., and Horn, R. (2006). WIE. Wechsler Intelligenztest fuer Erwachsene, Harcourt."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s001120170107","article-title":"Perzentile f\u00fcr den Body-mass-Index f\u00fcr das Kindes- und Jugendalter unter Heranziehung verschiedener deutscher Stichproben","volume":"149","author":"Wabitsch","year":"2001","journal-title":"Mon. Kinderheilkd."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1055\/s-0030-1253666","article-title":"[Percentiles of body mass index of 18-80-year-old German adults based on data from the Second National Nutrition Survey]","volume":"135","author":"Hemmelmann","year":"2010","journal-title":"Dtsch. Med. Wochenschr."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J. Biomed. Inform."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.brainres.2012.08.034","article-title":"Reward processing and intertemporal decision making in adults and adolescents: The role of impulsivity and decision consistency","volume":"1478","author":"Ripke","year":"2012","journal-title":"Brain Res."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1038\/s41598-017-02334-7","article-title":"Reliability in adolescent fMRI within two years\u2014A comparison of three tasks","volume":"7","author":"Vetter","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_51","first-page":"13","article-title":"Nipype: A Flexible, Lightweight and Extensible Neuroimaging Data Processing Framework in Python","volume":"5","author":"Gorgolewski","year":"2011","journal-title":"Front. Aging Neurosci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neuroimage.2007.07.007","article-title":"A fast diffeomorphic image registration algorithm","volume":"38","author":"Ashburner","year":"2007","journal-title":"NeuroImage"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1162\/jocn_a_00698","article-title":"Common Neural Correlates of Intertemporal Choices and Intelligence in Adolescents","volume":"27","author":"Ripke","year":"2015","journal-title":"J. Cogn. Neurosci."},{"key":"ref_54","unstructured":"Matthew, B., Jean-Luc, A., Romain, V., and Jean-Baptiste, P. (2002, January 2\u20136). Region of interest analysis using an SPM toolbox. Proceedings of the 8th International Conference on Functional Mapping of the Human Brain, Sendai, Japan."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/brain.2012.0073","article-title":"Conn: A functional connectivity toolbox for correlated and anticorrelated brain networks","volume":"2","year":"2012","journal-title":"Brain Connect."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1162\/089892903321593117","article-title":"A Parametric Manipulation of Factors Affecting Task-induced Deactivation in Functional Neuroimaging","volume":"15","author":"McKiernan","year":"2003","journal-title":"J. Cogn. Neurosci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev-clinpsy-032511-143049","article-title":"Default Mode Network Activity and Connectivity in Psychopathology","volume":"8","author":"Ford","year":"2012","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.bandc.2004.09.016","article-title":"Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning","volume":"56","author":"Ridderinkhof","year":"2004","journal-title":"Brain Cogn."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.neuroimage.2017.08.024","article-title":"An adaptive, individualized fMRI delay discounting procedure to increase flexibility and optimize scanner time","volume":"161","author":"Koffarnus","year":"2017","journal-title":"Neuroimage"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.brat.2014.07.007","article-title":"Hungry for reward: How can neuroscience inform the development of treatment for Anorexia Nervosa?","volume":"62","author":"Park","year":"2014","journal-title":"Behav. Res. Ther."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"13868","DOI":"10.1523\/JNEUROSCI.2602-15.2015","article-title":"How does the brain implement adaptive decision making to eat?","volume":"35","author":"Compan","year":"2015","journal-title":"J. Neurosci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/YCO.0000000000000544","article-title":"Neuroimaging and eating disorders","volume":"32","author":"Frank","year":"2019","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.neubiorev.2016.09.032","article-title":"A systematic review of resting-state functional-MRI studies in anorexia nervosa: Evidence for functional connectivity impairment in cognitive control and visuospatial and body-signal integration","volume":"71","author":"Gaudio","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Simon, J.J., Stopyra, M.A., and Friederich, H.-C. (2019). Neural Processing of Disorder-Related Stimuli in Patients with Anorexia Nervosa: A Narrative Review of Brain Imaging Studies. J. Clin. Med., 8.","DOI":"10.3390\/jcm8071047"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"9673","DOI":"10.1073\/pnas.0504136102","article-title":"The human brain is intrinsically organized into dynamic, anticorrelated functional networks","volume":"102","author":"Fox","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/hbm.22202","article-title":"Increased resting state functional connectivity in the default mode network in recovered anorexia nervosa","volume":"35","author":"Cowdrey","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3389\/fnbeh.2014.00346","article-title":"Increased resting state functional connectivity in the fronto-parietal and default mode network in anorexia nervosa","volume":"8","author":"Boehm","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1503\/jpn.130046","article-title":"Reduced salience and default mode network activity in women with anorexia nervosa","volume":"39","author":"McFadden","year":"2014","journal-title":"J. Psychiatry Neurosci."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1080\/15622975.2016.1249951","article-title":"Self and other body perception in anorexia nervosa: The role of posterior DMN nodes","volume":"19","author":"Via","year":"2018","journal-title":"World J. Biol. Psychiatry"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/scan\/nss093","article-title":"Who am I? How do I look? Neural differences in self-identity in anorexia nervosa","volume":"9","author":"McAdams","year":"2014","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"5207","DOI":"10.1002\/hbm.23005","article-title":"Neural responses to kindness and malevolence differ in illness and recovery in women with anorexia nervosa","volume":"36","author":"McAdams","year":"2015","journal-title":"Hum. Brain Mapp."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2016.12.005","article-title":"Neural activations are related to body-shape, anxiety, and outcomes in adolescent anorexia nervosa","volume":"87","author":"Xu","year":"2017","journal-title":"J. Psychiatr. Res."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/1047840X.2017.1323463","article-title":"Finding The \u201cSelf\u201d in Self-Regulation: The Identity-Value Model","volume":"28","author":"Berkman","year":"2017","journal-title":"Psychol. Inq."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.neuroimage.2011.05.028","article-title":"How is our self related to midline regions and the default-mode network?","volume":"57","author":"Qin","year":"2011","journal-title":"NeuroImage"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.neuroimage.2016.02.022","article-title":"Mapping the self in the brain\u2019s default mode network","volume":"132","author":"Davey","year":"2016","journal-title":"NeuroImage"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3758\/PBR.16.3.457","article-title":"One-year temporal stability of delay-discount rates","volume":"16","author":"Kirby","year":"2009","journal-title":"Psychon. Bull. Rev."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.beproc.2011.02.007","article-title":"Delay discounting: Trait variable?","volume":"87","author":"Odum","year":"2011","journal-title":"Behav. Process."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.tics.2015.09.005","article-title":"The Malleability of Intertemporal Choice","volume":"20","author":"Lempert","year":"2016","journal-title":"Trends Cogn. Sci. (Regul. Ed.)"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1467-8624.2008.01244.x","article-title":"Age Differences in Future Orientation and Delay Discounting","volume":"80","author":"Steinberg","year":"2009","journal-title":"Child Dev."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/scan\/nsq046","article-title":"What is for me is not for you: Brain correlates of intertemporal choice for self and other","volume":"6","author":"Albrecht","year":"2011","journal-title":"Soc. Cogn. Affect. Neurosci."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s40337-019-0251-5","article-title":"Set-shifting, central coherence and decision-making in individuals recovered from anorexia nervosa: A systematic review","volume":"7","author":"Fuglset","year":"2019","journal-title":"J. Eat. Disord."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/YCO.0000000000000540","article-title":"The promise of neurobiological research in anorexia nervosa","volume":"32","author":"Steinglass","year":"2019","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.neubiorev.2008.09.002","article-title":"Default-mode brain dysfunction in mental disorders: A systematic review","volume":"33","author":"Broyd","year":"2009","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jaac.2018.09.433","article-title":"Increased Functional Connectivity between Ventral Attention and Default Mode Networks in Adolescents with Bulimia Nervosa","volume":"58","author":"Domakonda","year":"2019","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"e01205","DOI":"10.1002\/brb3.1205","article-title":"Resting-state connectivity within and across neural circuits in anorexia nervosa","volume":"9","author":"Uniacke","year":"2019","journal-title":"Brain Behav."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jaac.2018.11.005","article-title":"Editorial: Connecting the Nodes of Altered Brain Network Organization in Eating Disorders","volume":"58","author":"Ehrlich","year":"2019","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/4\/900\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:11:18Z","timestamp":1760173878000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/4\/900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,25]]},"references-count":86,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4]]}},"alternative-id":["jcm9040900"],"URL":"https:\/\/doi.org\/10.3390\/jcm9040900","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,25]]}}}