{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:45:26Z","timestamp":1783597526619,"version":"3.55.0"},"reference-count":41,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T00:00:00Z","timestamp":1586390400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p> Umbilical cord milking (UCM) could be an alternative in cases where delayed umbilical cord clamping cannot be performed, therefore our objective was to evaluate the effects of UCM in newborns &lt;37 weeks\u2019 gestation. In this systematic review and meta-analysis, we searched MEDLINE, EMBASE, CINAHL, the Cochrane Database of Clinical Trials, the clinicaltrails.gov database for randomized UCM clinical trials with no language restrictions, which we then compared with other strategies. The sample included 2083 preterm infants. The results of our meta-analysis suggest that UCM in premature infants can reduce the risk of transfusion (relative risk (RR)= 0.78 [95% confidence interval (CI),0.67\u20130.90]) and increase hemoglobin(pooled weighted mean difference (PWMD)= 0.89 g\/L[95%CI 0.55\u20131.22]) and mean blood pressure (PWMD=1.92 mmHg [95% CI 0.55\u20133.25]). Conversely, UCM seems to increase the risk of respiratory distress syndrome (RR = 1.54 [95% CI 1.03\u20132.29]), compared to the control groups. In infants born at &lt;33 weeks, UCM was associated with a reduced risk of transfusion (RR= 0.81 [95%CI 0.66\u20130.99]), as well as higher quantities of hemoglobin (PWMD= 0.91 g\/L[95%CI 0.50\u20131.32]). UCM reduces the risk of transfusion in preterm infants, and increases initial hemoglobin, hematocrit, and mean blood pressure levels with respect to controls.<\/jats:p>","DOI":"10.3390\/jcm9041071","type":"journal-article","created":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T14:42:03Z","timestamp":1586443323000},"page":"1071","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Umbilical Cord Milking in Infants Born at &lt;37 Weeks of Gestation: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"9","author":[{"given":"Inmaculada","family":"Ortiz-Esquinas","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynaecology, Alc\u00e1zar de San Juan, 13600 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9053-7730","authenticated-orcid":false,"given":"Juan","family":"G\u00f3mez-Salgado","sequence":"additional","affiliation":[{"name":"Department of Sociology, Social Work and Public Health, University of Huelva, 21071 Huelva, Spain"},{"name":"Safety and Health Postgraduate Programme, Esp\u00edritu Santo University, Guayaquil 091650, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6239-2842","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Rodriguez-Almagro","sequence":"additional","affiliation":[{"name":"Department of Nursing, Faculty of Nursing of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9053-7730","authenticated-orcid":false,"given":"\u00c1ngel","family":"Arias-Arias","sequence":"additional","affiliation":[{"name":"Research Support Unit, \u201cMancha-Centro\u201d Hospital, Alc\u00e1zar de San Juan, 13600 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Ballesta-Castillejos","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, Hospital Talavera de la Reina, 45600 Toledo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9100-1134","authenticated-orcid":false,"given":"Antonio","family":"Hern\u00e1ndez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, Alc\u00e1zar de San Juan, 13600 Ciudad Real, Spain"},{"name":"Department of Nursing, Faculty of Nursing of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/jp.2016.151","article-title":"Placental transfusion: A review","volume":"37","author":"Katheria","year":"2017","journal-title":"J. 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