{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:05:59Z","timestamp":1762956359700,"version":"build-2065373602"},"reference-count":108,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>When preparing for the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the coronavirus infection disease (COVID-19) questions arose regarding various aspects concerning the anaesthetist. When reviewing the literature it became obvious that keeping up-to-date with all relevant publications is almost impossible. We searched for and summarised clinically relevant topics that could help making clinical decisions. This is a subjective analysis of literature concerning specific topics raised in our daily practice (e.g., clinical features of COVID-19 patients; ventilation of the critically ill COVID-19 patient; diagnostic of infection with SARS-CoV-2; stability of the virus; Covid-19 in specific patient populations, e.g., paediatrics, immunosuppressed patients, patients with hypertension, diabetes mellitus, kidney or liver disease; co-medication with non-steroidal anti-inflammatory drugs (NSAIDs); antiviral treatment) and we believe that these answers help colleagues in clinical decision-making. With ongoing treatment of severely ill COVID-19 patients other questions will come up. While respective guidelines on these topics will serve clinicians in clinical practice, regularly updating all guidelines concerning COVID-19 will be a necessary, although challenging task in the upcoming weeks and months. All recommendations during the current extremely rapid development of knowledge must be evaluated on a daily basis, as suggestions made today may be out-dated with the new evidence available tomorrow.<\/jats:p>","DOI":"10.3390\/jcm9051495","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T10:53:59Z","timestamp":1589540039000},"page":"1495","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant Management"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4412-9183","authenticated-orcid":false,"given":"Benedikt","family":"Preckel","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"},{"name":"Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus J.","family":"Schultz","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"},{"name":"Department of Intensive Care, and Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"},{"name":"Mahidol\u2013Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, 420\/6 Rajvithi Road, Bangkok 10400, Thailand"},{"name":"Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Build, Roosevelt Dr, Headington, Oxford OX3 7DQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3453-7186","authenticated-orcid":false,"given":"Alexander P.","family":"Vlaar","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"},{"name":"Department of Intensive Care, and Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9101-7649","authenticated-orcid":false,"given":"Abraham H.","family":"Hulst","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen","family":"Hermanides","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menno D.","family":"de Jong","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology &amp; Infection prevention, Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang S.","family":"Schlack","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0032-860X","authenticated-orcid":false,"given":"Markus F.","family":"Stevens","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3079-4115","authenticated-orcid":false,"given":"Robert P.","family":"Weenink","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus W.","family":"Hollmann","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands"},{"name":"Laboratory of Experimental Intensive Care and Anesthesiology (L\u00b7E\u00b7I\u00b7C\u00b7A), Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Roussel, Y., Giraud-Gatineau, A., Jimeno, M.-T., Rolain, J.-M., Zandotti, C., Colson, P., and Raoult, D. 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