{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:58:19Z","timestamp":1760237899030,"version":"build-2065373602"},"reference-count":46,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University Hospital of Tours","award":["No grant number (funding for english revision of the manuscript)"],"award-info":[{"award-number":["No grant number (funding for english revision of the manuscript)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Post-traumatic stress disorder (PTSD) is highly prevalent among patients hospitalized for an alcohol use disorder (AUD). Hospitalization can improve PTSD and AUD outcomes in some but not all patients, but we lack data on the baseline predictors of PTSD non-remission. This study aimed to determine the baseline risk factors for non-remitted PTSD in patients hospitalized for an AUD. Of 298 AUD inpatients recruited in a rehabilitation center (Le Courbat, France), we included 91 AUD inpatients with a co-occurring PTSD and a longitudinal assessment at baseline (T1) and before discharge (T2: 8 weeks later). Patients were assessed for PTSD diagnosis\/severity (PCL-5=PTSD Checklist for DSM-5), different types of trauma including childhood trauma (LEC-5=Life Events Checklist for DSM-5\/CTQ-SF=Childhood Trauma Questionnaire, Short-Form), and AUD diagnosis\/severity (clinical interview\/AUDIT=Alcohol Use Disorders Identification Test). Rate of PTSD remission between T1 and T2 was 74.1%. Non-remitted PTSD at T2 was associated with a history of childhood trauma (physical, emotional or sexual abuse, physical negligence), but not with other types of trauma experienced, nor baseline PTSD or AUD severity. Among patients hospitalized for an AUD with co-occurring PTSD, PTSD remission was more strongly related to the existence of childhood trauma than to AUD or PTSD severity at admission. These patients should be systematically screened for childhood trauma in order to tailor evidence-based interventions.<\/jats:p>","DOI":"10.3390\/jcm9072054","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T14:29:39Z","timestamp":1593527379000},"page":"2054","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Childhood Trauma Predicts Less Remission from PTSD among Patients with Co-Occurring Alcohol Use Disorder and PTSD"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9317-228X","authenticated-orcid":false,"given":"Paul","family":"Brunault","sequence":"first","affiliation":[{"name":"CHRU de Tours, Service d\u2019Addictologie Universitaire, \u00c9quipe de Liaison et de Soins en Addictologie, 37044 Tours, France"},{"name":"CHRU de Tours, Clinique Psychiatrique Universitaire, 37044 Tours, France"},{"name":"UMR 1253, iBrain, Universit\u00e9 de Tours, Inserm, 37020 Tours, France"},{"name":"Qualipsy EE 1901, Universit\u00e9 de Tours, 37020 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Lebigre","sequence":"additional","affiliation":[{"name":"CHRU de Tours, Service d\u2019Addictologie Universitaire, \u00c9quipe de Liaison et de Soins en Addictologie, 37044 Tours, France"},{"name":"CHRU de Tours, Clinique Psychiatrique Universitaire, 37044 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Idbrik","sequence":"additional","affiliation":[{"name":"Soins de Suite et de R\u00e9adaptation en Addictologie \u201cLe Courbat\u201d, 37460 Le Li\u00e8ge, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Maug\u00e9","sequence":"additional","affiliation":[{"name":"CHRU de Tours, Service d\u2019Addictologie Universitaire, \u00c9quipe de Liaison et de Soins en Addictologie, 37044 Tours, France"},{"name":"CHRU de Tours, Centre de Soins d\u2019Accompagnement et de Pr\u00e9vention en Addictologie CSAPA-37, 37044 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Adam","sequence":"additional","affiliation":[{"name":"Soins de Suite et de R\u00e9adaptation en Addictologie \u201cLe Courbat\u201d, 37460 Le Li\u00e8ge, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Servane","family":"Barrault","sequence":"additional","affiliation":[{"name":"Qualipsy EE 1901, Universit\u00e9 de Tours, 37020 Tours, France"},{"name":"CHRU de Tours, Centre de Soins d\u2019Accompagnement et de Pr\u00e9vention en Addictologie CSAPA-37, 37044 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-5401","authenticated-orcid":false,"given":"Gr\u00e9goire","family":"Baudin","sequence":"additional","affiliation":[{"name":"Qualipsy EE 1901, Universit\u00e9 de Tours, 37020 Tours, France"},{"name":"Laboratory of Psychopathology and Health Processes EA 4057, University Paris Descartes, Sorbonne Paris Cit\u00e9, 92100 Boulogne-Billancourt, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Courtois","sequence":"additional","affiliation":[{"name":"CHRU de Tours, Clinique Psychiatrique Universitaire, 37044 Tours, France"},{"name":"Qualipsy EE 1901, Universit\u00e9 de Tours, 37020 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2779-9612","authenticated-orcid":false,"given":"Hussein","family":"El Ayoubi","sequence":"additional","affiliation":[{"name":"CHRU de Tours, Service d\u2019Addictologie Universitaire, \u00c9quipe de Liaison et de Soins en Addictologie, 37044 Tours, France"},{"name":"CHRU de Tours, Centre de Soins d\u2019Accompagnement et de Pr\u00e9vention en Addictologie CSAPA-37, 37044 Tours, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Grall-Bronnec","sequence":"additional","affiliation":[{"name":"Addictology and Psychiatry Department, H\u00f4pital Saint Jacques, University Hospital of Nantes, 85 rue Saint Jacques, Cedex 1, 44093 Nantes, France"},{"name":"Inserm, SPHERE U1246 methodS in Patients-Centered Outcomes and HEalth ResEarch, Universit\u00e9 de Nantes, Universit\u00e9 de Tours, 22 boulevard Benoni Goullin, 44200 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coraline","family":"Hingray","sequence":"additional","affiliation":[{"name":"P\u00f4le Universitaire du Grand Nancy, Centre Psychoth\u00e9rapique de Nancy, 54520 Laxou, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Ballon","sequence":"additional","affiliation":[{"name":"CHRU de Tours, Service d\u2019Addictologie Universitaire, \u00c9quipe de Liaison et de Soins en Addictologie, 37044 Tours, 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