{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:08:44Z","timestamp":1789430924380,"version":"build-2803163510"},"reference-count":107,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Small-intestinal neuroendocrine tumors (SI-NETs) are the most prevalent small bowel neoplasms with an increasing frequency. In the multimodal management of SI-NETs, surgery plays a key role, either in curative intent, even if R0 resection is feasible in only 20% of patients due to advanced stage at diagnosis, or palliative intent. Surgeons must be informed about the specific surgical management of SI-NETs according to their hormonal secretion, their usual dissemination at the time of diagnosis and the need for bowel-preserving surgery to avoid short bowel syndrome. The aim of this paper is to review the surgical indications and techniques, and perioperative and postoperative management of SI-NETs.<\/jats:p>","DOI":"10.3390\/jcm9072319","type":"journal-article","created":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T03:23:16Z","timestamp":1595388196000},"page":"2319","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Surgery and Perioperative Management in Small Intestinal Neuroendocrine Tumors"],"prefix":"10.3390","volume":"9","author":[{"given":"Sophie","family":"Deguelte","sequence":"first","affiliation":[{"name":"Digestive Surgery Department, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"},{"name":"Clinical Research Department, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4528-5471","authenticated-orcid":false,"given":"Marine","family":"Perrier","sequence":"additional","affiliation":[{"name":"Department of Hepato-Gastroenterology and Digestive Oncology, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryne","family":"Hammoutene","sequence":"additional","affiliation":[{"name":"Digestive Surgery Department, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Cadiot","sequence":"additional","affiliation":[{"name":"Department of Hepato-Gastroenterology and Digestive Oncology, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Kianmanesh","sequence":"additional","affiliation":[{"name":"Digestive Surgery Department, Reims University Hospital, Robert Debr\u00e9 Hospital, F-51092 Reims, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1001\/jamaoncol.2017.0589","article-title":"Trends in the Incidence, Prevalence, and Survival Outcomes in Patients with Neuroendocrine Tumors in the United States","volume":"3","author":"Dasari","year":"2017","journal-title":"JAMA Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1677\/ERC-08-0017","article-title":"Prognostic factors of long-term outcome in gastroenteropancreatic neuroendocrine tumours","volume":"15","author":"Pape","year":"2008","journal-title":"Endocr. 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