{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:37:03Z","timestamp":1771659423992,"version":"3.50.1"},"reference-count":34,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T00:00:00Z","timestamp":1598313600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: the aim of this study was to assess the 2-year pulp survival of deep carious lesions in teeth excavated using a self-limiting protocol in a single-blind randomized controlled clinical trial. Methods: At baseline, 101 teeth with deep carious lesions in 86 patients were excavated randomly using self-limiting or control protocols. Standardized clinical examination and periapical radiographs of teeth were performed after 1- and 2-year follow-ups (REC 14\/LO\/0880). Results: During the 2-year period of the study, 24 teeth failed (16 and 8 at T12 and T24, respectively). Final analysis shows that 39\/63 (61.9%) of teeth were deemed successful (16\/33 (48.4%) and 23\/30 (76.6%) in the control and experimental groups, respectively with a statistically significant difference (z score = 2.3, p = 0.021). Of teeth with severe and mild symptoms at T0, 42.9% and 36.7% respectively failed at T24 (p &gt; 0.05). Within the self-limiting group, there was a lower success in premolars compared to molars (p &lt; 0.05). Conclusion: after 2 years, there was a statistically significant higher pulp survival rate of teeth with deep carious lesions excavated using self-limiting protocols in patients with reversible pulpitis. Molars showed higher success than premolars in teeth excavated using the self-limiting protocol. There was no statistically significant association between the outcome and the severity of symptoms at T0 (ClinicalTrials.gov NCT03071588).<\/jats:p>","DOI":"10.3390\/jcm9092738","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T09:30:07Z","timestamp":1598347807000},"page":"2738","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Self-Limiting versus Rotary Subjective Carious Tissue Removal: A Randomized Controlled Clinical Trial\u20142-Year Results"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1083-9913","authenticated-orcid":false,"given":"Ahmed H.","family":"Ali","sequence":"first","affiliation":[{"name":"Aesthetic and Restorative Dentistry Department, College of Dentistry, University of Baghdad, Baghdad 10001, Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah Ben","family":"Thani","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry, Oral &amp; Craniofacial Sciences, King\u2019s College London Floor 22 Tower Wing, Guy\u2019s Dental Hospital, London SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6901-0280","authenticated-orcid":false,"given":"Federico","family":"Foschi","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry, Oral &amp; Craniofacial Sciences, King\u2019s College London Floor 22 Tower Wing, Guy\u2019s Dental Hospital, London SE1 9RT, UK"},{"name":"Department of Therapeutic Dentistry, I. M. Sechenov First Moscow State Medical University, 119146 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0091-7348","authenticated-orcid":false,"given":"Avijit","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Conservative &amp; MI Dentistry, Faculty of Dentistry, Oral &amp; Craniofacial Sciences, King\u2019s College London Floor 25 Tower Wing, Guy\u2019s Dental Hospital, London SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0560-1054","authenticated-orcid":false,"given":"Francesco","family":"Mannocci","sequence":"additional","affiliation":[{"name":"Department of Endodontics, Faculty of Dentistry, Oral &amp; Craniofacial Sciences, King\u2019s College London Floor 22 Tower Wing, Guy\u2019s Dental Hospital, London SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0140-6736(07)60031-2","article-title":"Dental caries","volume":"369","author":"Selwitz","year":"2007","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/iej.13080","article-title":"European Society of Endodontology position statement: Management of deep caries and the exposed pulp","volume":"52","author":"Duncan","year":"2019","journal-title":"Int. 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