{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T12:21:25Z","timestamp":1768998085665,"version":"3.49.0"},"reference-count":25,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T00:00:00Z","timestamp":1599868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Treatment of cholangitis complicating choledocholithiasis includes biliary sphincterotomy and stone extraction. In certain cases of elderly comorbid patients with high risk for definitive endoscopic treatment, biliary stenting is the only measure for relieving biliary obstruction. Aim: We aimed to report the safety of retained biliary stone. Methods: a multi-center, retrospective case-control study conducted at two Israeli medical centers from January 2013 to December 2018 including all patients 18 years of age or older who underwent ERCP and biliary stent insertion for the treatment of acute cholangitis due to choledocholithiasis. Results: Three-hundred and eight patients were identified. Eighty-three patients had retained long-term biliary stents of more than 6 months (group A) from insertion compared to 225 patients whose biliary stents were removed within a 6-month period (group B). The mean follow-up in group A was 66.1\u00b1 16.3 vs. 11.1 \u00b1 2.7 weeks in group B. Overall complications during the follow-up were similar between groups A and B (6% vs. 4.9%, OR 1.24, Chi square 0.69). Similarly, the rate of each complication alone was not different when comparing group A to group B (3.6%, 1.2% and 1.2% vs. 2.7%, 0.44% and 1.8%) for cholangitis, stent related pancreatitis and biliary colic, respectively (Chi square 0.85). Even after 12 months, the rates of overall complications and each complication alone were not higher compared to less than 12 months (Chi square 0.72 and 0.8, respectively). Conclusion: endoscopic biliary stenting for cholangitis complicating choledocholithiasis is safe for the long-term period without increase in stent related complications.<\/jats:p>","DOI":"10.3390\/jcm9092953","type":"journal-article","created":{"date-parts":[[2020,9,13]],"date-time":"2020-09-13T21:11:32Z","timestamp":1600031492000},"page":"2953","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Long-Term Safety of Endoscopic Biliary Stents for Cholangitis Complicating Choledocholithiasis: A Multi-Center Study"],"prefix":"10.3390","volume":"9","author":[{"given":"Wisam","family":"Sbeit","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Galilee Medical Center, Nahariya 2221006, Israel"},{"name":"Faculty of Medicine in the Galilee, Bar-Ilan University, Safed 13100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6699-8625","authenticated-orcid":false,"given":"Tawfik","family":"Khoury","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Galilee Medical Center, Nahariya 2221006, Israel"},{"name":"Faculty of Medicine in the Galilee, Bar-Ilan University, Safed 13100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4738-3390","authenticated-orcid":false,"given":"Anas","family":"Kadah","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Galilee Medical Center, Nahariya 2221006, Israel"},{"name":"Faculty of Medicine in the Galilee, Bar-Ilan University, Safed 13100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"M. Livovsky","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Sha\u2019arei Zedek Medical Center, Jerusalem 9103102, Israel"},{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-0697","authenticated-orcid":false,"given":"Adi","family":"Nubani","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Sha\u2019arei Zedek Medical Center, Jerusalem 9103102, Israel"},{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Mari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine in the Galilee, Bar-Ilan University, Safed 13100, Israel"},{"name":"Gastroenterology and Endoscopy Units, The Nazareth Hospital, EMMS, Nazareth 16100, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eran","family":"Goldin","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Sha\u2019arei Zedek Medical Center, Jerusalem 9103102, Israel"},{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmud","family":"Mahamid","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Sha\u2019arei Zedek Medical Center, Jerusalem 9103102, Israel"},{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6314","DOI":"10.3748\/wjg.v13.i47.6314","article-title":"Role of endoscopic retrograde cholangiopancreatography in acute pancreatitis","volume":"13","author":"Canlas","year":"2007","journal-title":"World J. 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