{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:15:13Z","timestamp":1787242513430,"version":"build-2736575974"},"reference-count":25,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013511","name":"Silm\u00e4s\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100013511","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Finnish Ophthalmological Society","award":["NA"],"award-info":[{"award-number":["NA"]}]},{"DOI":"10.13039\/501100011905","name":"Evald ja Hilda Nissin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100011905","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007417","name":"Paulon S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100007417","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016033","name":"Waldemar von Frenckell Foundation","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/501100016033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The present study estimated the 5-year cumulative probability of Nd:YAG laser posterior capsulotomy according to the diopter power of implanted hydrophobic acrylic intraocular lenses (IOLs). Data were retrospectively collected of 15,375 eyes having cataract surgery and in-the-bag implantation of hydrophobic acrylic monofocal IOLs at the Ophthalmology Unit of Kymenlaakso Central Hospital, Kotka, Finland between the years 2007 and 2016. The cumulative probability of Nd:YAG capsulotomy was calculated by Kaplan\u2013Meier estimates, and potential risk factors were analyzed using the Cox proportional hazards model. The 5-year cumulative probability of Nd:YAG capsulotomy after cataract surgery was 27.4% (95% confidence interval (CI) 22.9\u201332.6%) for low-diopter (5\u201316.5 D) IOLs, 14.6% (13.8\u201315.5%) for mid-diopter (17\u201324.5 D) IOLs, and 13.6% (11.7\u201315.6%) for high-diopter (25\u201330 D) IOLs. A multivariate Cox regression analysis showed that low-diopter IOLs (HR 1.76; 95% CI 1.38\u20132.25; p &lt; 0.001) were associated with an increased risk of Nd:YAG capsulotomy compared to mid-diopter IOLs over the follow-up period after accounting for other predictors. Real-world evidence shows that low-diopter IOLs are associated with significantly higher risk of Nd:YAG capsulotomy within five years following implantation. Estimation should help in evaluating the risks of cataract surgery in myopic eyes.<\/jats:p>","DOI":"10.3390\/jcm9103071","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T04:18:57Z","timestamp":1600921137000},"page":"3071","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Intraocular Lens Power, Myopia, and the Risk of Nd:YAG Capsulotomy after 15,375 Cataract Surgeries"],"prefix":"10.3390","volume":"9","author":[{"given":"Juha-Matti","family":"Lindholm","sequence":"first","affiliation":[{"name":"Helsinki Retina Research Group, University of Helsinki, 00290 Helsinki, Finland"},{"name":"Department of Ophthalmology, Helsinki University Hospital, 00290 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkka","family":"Laine","sequence":"additional","affiliation":[{"name":"Helsinki Retina Research Group, University of Helsinki, 00290 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1550-8125","authenticated-orcid":false,"given":"Raimo","family":"Tuuminen","sequence":"additional","affiliation":[{"name":"Helsinki Retina Research Group, University of Helsinki, 00290 Helsinki, Finland"},{"name":"Kymenlaakso Central Hospital, Unit of Ophthalmology, 48210 Kotka, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0161-6420(00)00589-3","article-title":"Eradication of posterior capsule opacification: Documentation of a marked decrease in Nd:YAG laser posterior capsulotomy rates noted in an analysis of 5416 pseudophakic human eyes obtained postmortem","volume":"108","author":"Apple","year":"2001","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.ajo.2019.01.010","article-title":"Five-year cumulative incidence and risk factors of Nd:YAG capsulotomy in 10044 hydrophobic acrylic 1-piece and 3-piece IOLs","volume":"200","author":"Lindholm","year":"2019","journal-title":"Am. 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