{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:43:40Z","timestamp":1773125020557,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Paraneoplastic neurological syndromes (PNSs) are a heterogeneous group of rare immune-mediated diseases associated with cancer. The aim of this study was to investigate the prevalence of PNSs in the province of Brescia. PNS prevalence was calculated using the Lombardy regional hospital admission records from 1998 to 2003. We used the website \u201cEpidemiologic and Economic Atlas of Hospital Activities in Lombardy\u201d and the \u201cInternational Statistical Classification of Diseases and Related Health Problems\u201d. In the province of Brescia, we found 54 cases of PNSs, 29 with subacute neuropathies, five with paraneoplastic cerebellar degeneration and 20 with encephalomyelitis. Peripheral nervous system diseases were the most frequent neurological disorders. In Lombardy, the number of PNS patients admitted was 322 (133 with encephalomyelitis, 21 with paraneoplastic cerebellar degeneration, 166 with polyneuropathies and two with optic degeneration). In Lombardy, the prevalence of PNSs was 25 in 100,000 hospital admissions and 5.92 in 100,000 for the Lombardy population. Our results show a discrete presence of PNS patients in the province of Brescia and in the Lombardy region as a whole.<\/jats:p>","DOI":"10.3390\/jcm9103105","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T08:02:58Z","timestamp":1601280178000},"page":"3105","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Paraneoplastic Neurological Syndromes: Study of Prevalence in a Province of the Lombardy Region, Italy"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5894-8545","authenticated-orcid":false,"given":"Lorenzo","family":"Lorusso","sequence":"first","affiliation":[{"name":"ASST Lecco, UOC Neurology and Stroke Unit, 23807 Merate (LC), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenza","family":"Precone","sequence":"additional","affiliation":[{"name":"MAGI EUREGIO, 39100 Bolzano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Neurology, Simone Veil Hospital, 95600 Eaubonne, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaelle K.","family":"Ngonga","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Centre Emile Mayrisch, Esch-sur-Alzette, 4240 Luxembourg, Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5681-5861","authenticated-orcid":false,"given":"Antonio Giampiero","family":"Russo","sequence":"additional","affiliation":[{"name":"UOC Unit\u00e0 di Epidemiologia, ATS della Citt\u00e0 Metropolitana di Milano, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5551-7520","authenticated-orcid":false,"given":"Stefano","family":"Paolacci","sequence":"additional","affiliation":[{"name":"MAGI\u2019S LAB, 38068 Rovereto (TN), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9552-221X","authenticated-orcid":false,"given":"Matteo","family":"Bertelli","sequence":"additional","affiliation":[{"name":"MAGI EUREGIO, 39100 Bolzano, Italy"},{"name":"MAGI\u2019S LAB, 38068 Rovereto (TN), Italy"},{"name":"EBTNA-LAB, 38068 Rovereto (TN), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1750-1172-2-22","article-title":"Paraneoplastic neurological syndromes","volume":"2","author":"Honnorat","year":"2007","journal-title":"Orphanet J. 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