{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T11:50:32Z","timestamp":1786708232661,"version":"build-2736575974"},"reference-count":51,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2020,10,11]],"date-time":"2020-10-11T00:00:00Z","timestamp":1602374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>While satisfactory results have been reported during short-to mid-term follow-up assessments of hemophilic patients who have undergone total knee arthroplasty (TKA), limited literature focusing on long-term survival following TKA exists to date. As part of this investigation, a consecutive series of 78 TKAs in 56 patients with hemophilic arthropathy was reviewed. The mean patient age at the time of operation was 38.7 years old and the mean length of follow up was 10.2 years. Clinical and radiologic outcomes, quality of life, complications, and long-term survivorship of TKA were evaluated. At the latest point of follow up, the average American Knee Society (AKS) knee and function scores had improved from 32.1 to 85.7 points and 41.5 to 83.3 points, respectively. Moreover, the average range of motion (ROM) was significantly increased from 64.2\u00b0 preoperatively to 84.2\u00b0 postoperatively. The physical and mental Short Form-36 results were also significantly improved at the latest point of follow up. Postoperative complications appeared in 12 knees (15.4%). The readmission rate in the 30 days after discharge was 6.4%. Revision TKA was performed in three knees for periprosthetic joint infection (n = 2 knees) and tibial component loosening (n = 1 knee). The Kaplan\u2013Meier 10- and 13-year prosthesis survival rates were 97.1% and 93.2%, respectively. The current study suggests that the mid-to long-term results of TKA in patients with hemophilic arthropathy are favorable, with successful long-term prosthesis survival achievable in most cases.<\/jats:p>","DOI":"10.3390\/jcm9103247","type":"journal-article","created":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T05:45:51Z","timestamp":1602913551000},"page":"3247","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Mid-to Long-Term Survival of Total Knee Arthroplasty in Hemophilic Arthropathy"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9235-1347","authenticated-orcid":false,"given":"Jung-Kwon","family":"Bae","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul, 05278 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4010-1063","authenticated-orcid":false,"given":"Kang-Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul, 05278 Korea"},{"name":"Department of Orthopaedic Surgery, Kyung Hee University School of Medicine, Seoul 05278, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Hak","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul, 05278 Korea"},{"name":"Department of Orthopaedic Surgery, Kyung Hee University School of Medicine, Seoul 05278, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung-Chul","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul, 05278 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e275","DOI":"10.1111\/hae.12885","article-title":"Meta-analysis: Outcomes of total knee arthroplasty in the haemophilia population","volume":"22","author":"Moore","year":"2016","journal-title":"Haemophilia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00003086-199607000-00003","article-title":"Effects of hemophilia on articulations of children and adults","volume":"328","year":"1996","journal-title":"Clin. 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