{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:23:15Z","timestamp":1760239395475,"version":"build-2065373602"},"reference-count":56,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Excessive body weight and some concomitant diseases, such as psoriasis, accompany women treated due to infertility by intracytoplasmic sperm injection (ICSI). This study is aimed to assess effect of obesity and psoriasis on quality of egg cells, embryos, course of pregnancy, and state of a newborn after treatment with ICSI. A total of 140 women were included into the study (110 healthy women and 30 with psoriasis). Among healthy women, BMI negatively correlated with total recovery rate, total oocyte score, blastocyst formation rate (BFR) and amount and quality of blastocysts (r &lt; 0, p &lt; 0.001). The relationships were similar in psoriasis, however apart from average blastocyst quality (p = 0.17) and BFR (p = 0.352). In healthy patients, BMI negatively correlated with gestational age at delivery (r = \u22120.444, p = 0.010) and APGAR (r = \u22120.481, p = 0.005). An excess of adipose tissue exerts an unfavourable effect on female reproductive functions, especially with a simultaneous burden of psoriasis. Excessive body weight is conducive to development of gestational diabetes and shortens the duration of pregnancy. The burden of psoriasis in combination with excessive body weight has an impact on the risk of occurrence of intrauterine growth restriction of foetus. Overweight and obesity negatively affect the state of a newborn, measured using APGAR scale.<\/jats:p>","DOI":"10.3390\/jcm9113628","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T20:20:33Z","timestamp":1605126033000},"page":"3628","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Excessive Body Weight and Psoriasis in Women Undergoing ICSI Procedure and State of Health of the Newborn"],"prefix":"10.3390","volume":"9","author":[{"given":"Anita","family":"Wdowiak-Filip","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venerology and Pediatric Dermatology, Medical University of Lublin, ul. Radziwi\u0142\u0142owska 13, 20-080 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7011-2345","authenticated-orcid":false,"given":"Artur","family":"Wdowiak","sequence":"additional","affiliation":[{"name":"Diagnostic Techniques Unit, Medical University of Lublin, ul. Staszica 4\/6, 20-081 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota","family":"Raczkiewicz","sequence":"additional","affiliation":[{"name":"Institute of Statistics and Demography, Collegium of Economic Analysis, SGH Warsaw School of Economics, ul. Madali\u0144skiego 6\/8, 02-513 Warszawa, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Bartosi\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Cosmetology and Aesthetic Medicine, Medical University, Chodzki 1, 20-093 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3171-225X","authenticated-orcid":false,"given":"Iwona","family":"Bojar","sequence":"additional","affiliation":[{"name":"Institute of Rural Health in Lublin, ul. Jaczewskiego 2, 20-090 Lublin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.26444\/aaem\/76997","article-title":"Applicatin of dietetics in reproductive medicine","volume":"24","author":"Skrzypek","year":"2017","journal-title":"Ann. Agric. Environ. 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