{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:04:28Z","timestamp":1790715868225,"version":"4.1.0"},"reference-count":36,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Sarcoidosis is one of the leading causes of uveitis. To date, no studies have assessed the factors specifically related with recovery in ocular sarcoidosis. In this study, we aimed to determine factors associated with ocular and extraocular recovery in patients with sarcoid uveitis. Methods: A retrospective study of sarcoid uveitis, with a three-year minimum follow-up in Lyon University Hospital between December 2003 and December 2019. Patients presented biopsy-proven sarcoidosis or presumed sarcoid. Recovery was defined by a disease-free status, spontaneously or despite being off all treatments for three years or more. Results: 143 patients were included: 110 with biopsy-proven and 33 with presumed sarcoid uveitis. Seventy-one percent were women, the median age at presentation was 53 years, and 71% were Caucasian. Chronic uveitis was the main clinical presentation (75%), mostly panuveitis (48%) with bilateral involvement (82%). After a median follow-up of 83.5 months, recovery was reported in 26% of patients. In multivariable analysis, Caucasian ethnicity (p = 0.007) and anterior uveitis (p = 0.008) were significantly associated with recovery, while increased intraocular pressure was negatively associated (p = 0.039). Conclusion: In this large European cohort, one quarter of patients recovered. Caucasian ethnicity and anterior uveitis are associated with ocular and extraocular recovery.<\/jats:p>","DOI":"10.3390\/jcm9123894","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T20:10:22Z","timestamp":1606767022000},"page":"3894","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Factors Associated with Ocular and Extraocular Recovery in 143 Patients with Sarcoid Uveitis"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6101-2203","authenticated-orcid":false,"given":"Francois-Henri","family":"Bienvenu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital de la Croix-Rousse, Universit\u00e9 Claude Bernard Lyon 1, 69004 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9ophile","family":"Tiffet","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, P\u00f4le Sant\u00e9 Publique, Service de Biostatistique et Bioinformatique, F-69003 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Maucort-Boulch","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, P\u00f4le Sant\u00e9 Publique, Service de Biostatistique et Bioinformatique, F-69003 Lyon, France"},{"name":"CNRS, UMR 5558, Laboratoire de Biom\u00e9trie et Biologie \u00c9volutive, \u00c9quipe Biostatistique-Sant\u00e9, F-69100 Villeurbanne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Gerfaud-Valentin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital de la Croix-Rousse, Universit\u00e9 Claude Bernard Lyon 1, 69004 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3908-6716","authenticated-orcid":false,"given":"Laurent","family":"Kodjikian","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, H\u00f4pital de la Croix-Rousse, Universit\u00e9 Claude Bernard Lyon 1, 69004 Lyon, France"},{"name":"Laboratoire UMR-CNRS 5510 Mat\u00e9is, Universit\u00e9 Lyon 1, 69100 Villeurbanne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Perard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Centre Hospitalier Saint-Joseph Saint-Luc, Universit\u00e9 Claude Bernard Lyon 1, 69007 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Burillon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, H\u00f4pital Edouard Herriot, Universit\u00e9 Claude Bernard Lyon 1, 69003 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile-Audrey","family":"Durel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital Edouard Herriot, Universit\u00e9 Claude Bernard Lyon 1, 69003 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Hot","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital Edouard Herriot, Universit\u00e9 Claude Bernard Lyon 1, 69003 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5249-3650","authenticated-orcid":false,"given":"Yvan","family":"Jamilloux","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital de la Croix-Rousse, Universit\u00e9 Claude Bernard Lyon 1, 69004 Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3070-3842","authenticated-orcid":false,"given":"Pascal","family":"Seve","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, H\u00f4pital de la Croix-Rousse, Universit\u00e9 Claude Bernard Lyon 1, 69004 Lyon, France"},{"name":"Hospices Civils de Lyon, P\u00f4le IMER, Lyon F-69003, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,30]]},"reference":[{"key":"ref_1","unstructured":"Statement on Sarcoidosis (1999). 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