{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:28:11Z","timestamp":1760239691964,"version":"build-2065373602"},"reference-count":69,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T00:00:00Z","timestamp":1607990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Chordae tendineae rupture (CTR) is a potentially life-threatening cardiac event often resulting in Acute mitral regurgitation (AMR). We assessed Post-traumatic stress disorder (PTSD), depression, and anxiety symptoms in n=21 CTR patients with AMR (age 82.3 \u00b1 4.2 years; 66.7% men) and compared them to n=23 CTR patients with Chronic mitral regurgitation (CMR) and n=35 Myocardial infraction (MI) patients. Regression analyses revealed that PTSD scores were significantly higher in CTR patients with AMR than in CTR patients with CMR or MI patients. CTR patients with CMR had the lowest levels of PTSD-symptoms. Depression and anxiety scores were elevated across all three groups. Our results suggest that psychosocial factors need to be considered in CTR patients\u2019 care.<\/jats:p>","DOI":"10.3390\/jcm9124048","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T09:12:57Z","timestamp":1608023577000},"page":"4048","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Broken Heartstrings\u2014Post-Traumatic Stress Disorder and Psychological Burden after Acute Mitral Regurgitation Due to Chordae Tendineae Rupture"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7869-698X","authenticated-orcid":false,"given":"Anna","family":"Cranz","sequence":"first","affiliation":[{"name":"Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, University Hospital of Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8546-3335","authenticated-orcid":false,"given":"Anja","family":"Greinacher","sequence":"additional","affiliation":[{"name":"Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, University Hospital of Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3793-2541","authenticated-orcid":false,"given":"Ede","family":"Nagy","sequence":"additional","affiliation":[{"name":"Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, University Hospital of Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4344-8959","authenticated-orcid":false,"given":"Hans-Christoph","family":"Friederich","sequence":"additional","affiliation":[{"name":"Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, University Hospital of Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2293-2314","authenticated-orcid":false,"given":"Hugo A.","family":"Katus","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3431-3104","authenticated-orcid":false,"given":"Nicolas","family":"Geis","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7559-5502","authenticated-orcid":false,"given":"Sven T.","family":"Pleger","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2839-178X","authenticated-orcid":false,"given":"Christoph","family":"Nikendei","sequence":"additional","affiliation":[{"name":"Center for Psychosocial Medicine, Department of General Internal Medicine and Psychosomatics, University Hospital of Heidelberg, University of Heidelberg, 69115 Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0002-9343(85)90440-1","article-title":"Acute severe mitral regurgitation. 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