{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:58:27Z","timestamp":1761674307904,"version":"build-2065373602"},"reference-count":76,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:00:00Z","timestamp":1608163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Autoinflammatory disorders are commonly characterized by seemingly unprovoked systemic inflammation mainly driven by cells and cytokines of the innate immune system. In many disorders on this spectrum, joint and bone involvement may be observed and imaging of these manifestations can provide essential diagnostic information. This review aimed to provide a comprehensive overview of the imaging characteristics for major diseases and disease groups on the autoinflammatory spectrum, including familial Mediterranean fever (FMF), Beh\u00e7et disease (BD), crystal deposition diseases (including gout), adult-onset Still\u2019s disease (AoSD), and syndromatic synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO)\/chronic recurrent multifocal osteomyelitis (CRMO). Herein, we discuss common and distinguishing imaging characteristics, phenotypical overlaps with related diseases, and promising fields of future research.<\/jats:p>","DOI":"10.3390\/jcm9124074","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T21:21:49Z","timestamp":1608240109000},"page":"4074","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Imaging of Joints and Bones in Autoinflammation"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9763-2420","authenticated-orcid":false,"given":"Katharina","family":"Ziegeler","sequence":"first","affiliation":[{"name":"Department of Radiology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Eshed","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Tel Giborim Affiliated with the Sackler School of Medicine, Tel Aviv University, 52621 Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3593-1449","authenticated-orcid":false,"given":"Torsten","family":"Diekhoff","sequence":"additional","affiliation":[{"name":"Department of Radiology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6142-3814","authenticated-orcid":false,"given":"Kay Geert","family":"Hermann","sequence":"additional","affiliation":[{"name":"Department of Radiology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, 10117 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"McGonagle, D., and McDermott, M.F. (2006). A Proposed Classification of the Immunological Diseases. PLoS Med., 3.","DOI":"10.1371\/journal.pmed.0030297"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.clim.2016.03.002","article-title":"Shaping the spectrum\u2014From autoinflammation to autoimmunity","volume":"165","author":"Hedrich","year":"2016","journal-title":"Clin. Immunol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1016\/j.lpm.2018.08.014","article-title":"Familial Mediterranean Fever","volume":"48","author":"Ozdogan","year":"2019","journal-title":"Press. M\u00e9d."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/sj.ejhg.5200658","article-title":"The spectrum of Familial Mediterranean Fever (FMF) mutations","volume":"9","author":"Touitou","year":"2001","journal-title":"Eur. J. Hum. Genet."},{"key":"ref_5","first-page":"41","article-title":"The frequency of sacroiliitis in familial Mediterranean fever and the role of HLA-B27 and MEFV mutations in the development of sacroiliitis","volume":"28","author":"Cansu","year":"2008","journal-title":"Clin. Rheumatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1002\/art.27683","article-title":"Association of familial Mediterranean fever-related MEFV variations with ankylosing spondylitis","volume":"62","author":"Cosan","year":"2010","journal-title":"Arthritis Rheum."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1002\/art.38797","article-title":"Exertional Leg Pain in Familial Mediterranean Fever: A Manifestation of an Underlying Enthesopathy and a Marker of More Severe Disease","volume":"66","author":"Eshed","year":"2014","journal-title":"Arthritis Rheumatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1136\/ard.2007.070243","article-title":"MRI of enthesitis of the appendicular skeleton in spondyloarthritis","volume":"66","author":"Eshed","year":"2007","journal-title":"Ann. Rheum. Dis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3109\/03009742.2012.698301","article-title":"Exertional leg pain as a manifestation of occult spondyloarthropathy in familial Mediterranean fever: An MRI evaluation","volume":"41","author":"Eshed","year":"2012","journal-title":"Scand. J. Rheumatol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1136\/bjo.40.6.355","article-title":"Description of Behcet\u2019s Syndrome in the Hippocratic Third Book of Endemic Diseases","volume":"40","author":"Feigenbaum","year":"1956","journal-title":"Br. J. Ophthalmol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1002\/art.24642","article-title":"HLA-B51\/B5and the risk of Beh\u00e7et\u2019s disease: A systematic review and meta-analysis of case-control genetic association studies","volume":"61","author":"LaValley","year":"2009","journal-title":"Arthritis Rheum."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0049-0172(98)80001-2","article-title":"Beh\u00e7et\u2019s Disease","volume":"27","author":"Kaklamani","year":"1998","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_13","unstructured":"Adil, A., Goyal, A., Bansal, P., and Quint, J.M. (2020). Behcet Disease. StatPearls, StatPearls Publishing."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3904\/kjim.1999.14.1.66","article-title":"Clinical Analysis of Behcet Disease; Arthritic Manifestations in Behcet Disease may present as Seronegative Rheumatoid Arthritis or Palindromic Rheumatism","volume":"14","author":"Park","year":"1999","journal-title":"Korean J. Intern. Med."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/653806","article-title":"Musculoskeletal Findings in Behcet\u2019s Disease","volume":"2012","author":"Bicer","year":"2011","journal-title":"Pathol. Res. Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1136\/ard.40.6.558","article-title":"A controlled survey of sacroiliitis in Behcet\u2019s disease","volume":"40","author":"Yazici","year":"1981","journal-title":"Ann. Rheum. Dis."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/art.23450","article-title":"Increased enthesopathy among Beh\u00e7et\u2019s syndrome patients with acne and arthritis: An ultrasonography study","volume":"58","author":"Hatemi","year":"2008","journal-title":"Arthritis Rheum."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/s41584-020-0441-1","article-title":"Global epidemiology of gout: Prevalence, incidence, treatment patterns and risk factors","volume":"16","author":"Dehlin","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.autrev.2012.07.024","article-title":"Gout as autoinflammatory disease: New mechanisms for more appropriated treatment targets","volume":"12","author":"Punzi","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"ref_20","first-page":"516","article-title":"Molecular identification of a danger signal that alerts the immune system to dying cells","volume":"425","author":"Shi","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/0016-5085(83)90317-7","article-title":"Absorption of 151chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease","volume":"85","author":"Bjarnason","year":"1983","journal-title":"Gastroenterology"},{"key":"ref_22","first-page":"247","article-title":"Calcium crystals and auto-inflammation","volume":"59","author":"McCarthy","year":"2019","journal-title":"Rheumatology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3389\/fmed.2020.00166","article-title":"Autoinflammatory Mechanisms in Crystal-Induced Arthritis","volume":"7","author":"Oliviero","year":"2020","journal-title":"Front. Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/annrheumdis-2019-215315","article-title":"2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout","volume":"79","author":"Richette","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/ard.2010.139105","article-title":"European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: Terminology and diagnosis","volume":"70","author":"Zhang","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1136\/ard.62.6.513","article-title":"UK community prevalence of knee chondrocalcinosis: Evidence that correlation with osteoarthritis is through a shared association with osteophyte","volume":"62","author":"Neame","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"ref_27","first-page":"1241","article-title":"The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: The Framingham Study","volume":"16","author":"Felson","year":"1989","journal-title":"J. Rheumatol."},{"key":"ref_28","first-page":"819","article-title":"Prevalence of musculoskeletal conditions in an Italian population sample: Results of a regional community-based study. I. The MAPPING study","volume":"23","author":"Salaffi","year":"2005","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_29","first-page":"1","article-title":"Real-world treatment of gout and asymptomatic hyperuricemia: A cross-sectional study of Japanese health insurance claims data","volume":"10","author":"Koto","year":"2020","journal-title":"Mod. Rheumatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.1016\/j.semarthrit.2020.04.009","article-title":"Unravelling the mysteries of gout by multimodality imaging","volume":"50","author":"Abdellatif","year":"2020","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"40","DOI":"10.4103\/JMU.JMU_77_18","article-title":"Consistency of the sonographic image (double contour sign) in patients with gout after ambulation","volume":"27","author":"Checa","year":"2019","journal-title":"J. Med. Ultrasound"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/art.39959","article-title":"Performance of Ultrasound in the Diagnosis of Gout in a Multicenter Study: Comparison with Monosodium Urate Monohydrate Crystal Analysis as the Gold Standard","volume":"69","author":"Ogdie","year":"2017","journal-title":"Arthritis Rheumatol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1136\/annrheumdis-2014-205431","article-title":"Imaging modalities for the classification of gout: Systematic literature review and meta-analysis","volume":"74","author":"Ogdie","year":"2015","journal-title":"Ann. Rheum. Dis."},{"key":"ref_34","first-page":"746","article-title":"Ultrasound sensitivity to changes in gout: A longitudinal study after two years of treatment","volume":"35","author":"Peiteado","year":"2017","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.jbspin.2015.09.007","article-title":"In arthritis the Doppler based degree of hypervascularisation shows a positive correlation with synovial leukocyte count and distinguishes joints with leukocytes greater and less than 5\/nL","volume":"83","author":"Sattler","year":"2016","journal-title":"Jt. Bone Spine"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.semarthrit.2017.03.002","article-title":"Diagnostic accuracy of dual-energy computed tomography in patients with gout: A meta-analysis","volume":"47","author":"Lee","year":"2017","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1093\/rheumatology\/kez180","article-title":"The diagnostic performance of dual energy CT for diagnosing gout: A systematic literature review and meta-analysis","volume":"58","author":"Gamala","year":"2019","journal-title":"Rheumatology"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1136\/annrheumdis-2013-205095","article-title":"Dual-energy CT for the diagnosis of gout: An accuracy and diagnostic yield study","volume":"74","author":"Bongartz","year":"2015","journal-title":"Ann. Rheum. Dis."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s00330-019-06350-1","article-title":"Development and validation of a quantitative method for estimation of the urate burden in patients with gouty arthritis using dual-energy computed tomography","volume":"30","author":"Kotlyarov","year":"2020","journal-title":"Eur. Radiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s11926-012-0301-3","article-title":"Dual-Energy Computed Tomography for Gout Diagnosis and Management","volume":"15","author":"Dalbeth","year":"2013","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00256-016-2533-1","article-title":"Osteitis: A retrospective feasibility study comparing single-source dual-energy CT to MRI in selected patients with suspected acute gout","volume":"46","author":"Diekhoff","year":"2017","journal-title":"Skelet. Radiol."},{"key":"ref_42","first-page":"1194","article-title":"Identification of calcium pyrophosphate deposition disease (CPPD) by ultrasound: Reliability of the OMERACT definitions in an extended set of joints\u2014An international multiobserver study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force","volume":"77","author":"Filippou","year":"2018","journal-title":"Ann. Rheum. Dis."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.3899\/jrheum.161057","article-title":"Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force","volume":"44","author":"Filippou","year":"2017","journal-title":"J. Rheumatol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1148\/radiol.13130125","article-title":"Frequency of Atlantoaxial Calcium Pyrophosphate Dihydrate Deposition at CT","volume":"269","author":"Chang","year":"2013","journal-title":"Radiology"},{"key":"ref_45","first-page":"826","article-title":"Low-dose computed tomography as diagnostic tool in calcium pyrophosphate deposition disease arthropathy: Focus on ligamentous calcifications of the wrist","volume":"37","author":"Ziegeler","year":"2019","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.joca.2014.10.009","article-title":"CT imaging for evaluation of calcium crystal deposition in the knee: Initial experience from the Multicenter Osteoarthritis (MOST) study","volume":"23","author":"Misra","year":"2015","journal-title":"Osteoarthr. Cartil."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/RLI.0000000000000099","article-title":"Detection and Characterization of Crystal Suspensions Using Single-Source Dual-Energy Computed Tomography","volume":"50","author":"Diekhoff","year":"2015","journal-title":"Investig. Radiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1759720","DOI":"10.1177\/1759720X20936060","article-title":"Dual-energy computed-tomography-based discrimination between basic calcium phosphate and calcium pyrophosphate crystal deposition in vivo","volume":"12","author":"Pascart","year":"2020","journal-title":"Ther. Adv. Musculoskelet. Dis."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.joca.2019.05.007","article-title":"Dual-energy computed tomography in calcium pyrophosphate deposition: Initial clinical experience","volume":"27","author":"Pascart","year":"2019","journal-title":"Osteoarthr. Cartil."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11926-020-0890-1","article-title":"Utility of Ultrasound and Dual Energy CT in Crystal Disease Diagnosis and Management","volume":"22","author":"Filippou","year":"2020","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00256-019-03343-5","article-title":"Dual-energy CT in the differentiation of crystal depositions of the wrist: Does it have added value?","volume":"49","author":"Ziegeler","year":"2019","journal-title":"Skelet. Radiol."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Ziegeler, K., Richter, S.-T., Hermann, S., Hermann, K.G.A., Hamm, B., and Diekhoff, T. (2020). Dual-energy CT collagen density mapping of wrist ligaments reveals tissue remodeling in CPPD patients: First results from a clinical cohort. Skelet. Radiol., 1\u20137.","DOI":"10.1007\/s00256-020-03580-z"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.semarthrit.2018.10.009","article-title":"Spinal involvement with calcium pyrophosphate deposition disease in an academic rheumatology center: A series of 37 patients","volume":"48","author":"Moshrif","year":"2019","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"108653","DOI":"10.1016\/j.ejrad.2019.108653","article-title":"Calcium hydroxyapatite deposition disease: Imaging features and presentations mimicking other pathologies","volume":"120","author":"Hongsmatip","year":"2019","journal-title":"Eur. J. Radiol."},{"key":"ref_55","first-page":"186","article-title":"Rotator cuff calcific tendinopathy: From diagnosis to treatment","volume":"89","author":"Chianca","year":"2018","journal-title":"Acta Biomed."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.rcl.2017.04.004","article-title":"Conventional Radiology in Crystal Arthritis","volume":"55","author":"Jacques","year":"2017","journal-title":"Radiol. Clin. N. Am."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jse.2009.07.008","article-title":"Radiologic course of the calcific deposits in calcific tendinitis of the shoulder: Does the initial radiologic aspect affect the final results?","volume":"19","author":"Cho","year":"2010","journal-title":"J. Shoulder Elb. Surg."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0950-3579(89)80009-3","article-title":"Calcifying tendinitis","volume":"3","author":"Uhthoff","year":"1989","journal-title":"Bailli\u00e8res Clin. Rheumatol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ocl.2014.11.011","article-title":"Evaluation and Nonsurgical Management of Rotator Cuff Calcific Tendinopathy","volume":"46","author":"Greis","year":"2015","journal-title":"Orthop. Clin. N. Am."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s11926-004-0072-6","article-title":"Calcium pyrophosphate dihydrate and basic calcium phosphate crystalinduced arthropathies: Update on pathogenesis, clinical features, and Therapy","volume":"6","author":"Ea","year":"2004","journal-title":"Curr. Rheumatol. Rep."},{"key":"ref_61","first-page":"271","article-title":"Milwaukee shoulder syndrome","volume":"102","author":"McCarty","year":"1991","journal-title":"Trans. Am. Clin. Climatol. Assoc."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"bcr2013202183","DOI":"10.1136\/bcr-2013-202183","article-title":"Milwaukee shoulder (and knee) syndrome","volume":"2014","author":"Santiago","year":"2014","journal-title":"BMJ Case Rep."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/s41584-018-0081-x","article-title":"Mechanisms, biomarkers and targets for adult-onset Still\u2019s disease","volume":"14","author":"Feist","year":"2018","journal-title":"Nat. Rev. Rheumatol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.berh.2008.08.006","article-title":"Adult-onset Still disease","volume":"22","author":"Fautrel","year":"2008","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/00005792-199103000-00004","article-title":"Adult Still\u2019s disease: Manifestations, disease course, and outcome in 62 patients","volume":"70","author":"Pouchot","year":"1991","journal-title":"Medicine"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2174\/1573397113666170728124845","article-title":"Atypical form of Adult-onset Still\u2019s Disease with Distal Interphalangeal Joints Involvement","volume":"14","author":"Belghali","year":"2018","journal-title":"Curr. Rheumatol. Rev."},{"key":"ref_67","first-page":"212","article-title":"Chronic Recurrent Multifocal Osteomyelitis (CRMO) and Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) Syndrome\u2014Two Presentations of the Same Disease?","volume":"26","author":"Skerlev","year":"2018","journal-title":"Acta Dermatovenerol. Croat."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/rheumatology\/kel190","article-title":"Classification of Non-Bacterial Osteitis: Retrospective study of clinical, immunological and genetic aspects in 89 patients","volume":"46","author":"Jansson","year":"2007","journal-title":"Rheumatology"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1055\/s-0038-1639469","article-title":"SAPHO and CRMO: The Value of Imaging","volume":"22","author":"Klicman","year":"2018","journal-title":"Semin. Musculoskelet. Radiol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00247-012-2544-6","article-title":"Chronic recurrent multifocal osteomyelitis (CRMO): A longitudinal case series review","volume":"43","author":"Falip","year":"2013","journal-title":"Pediatr. Radiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1055\/s-2004-835364","article-title":"Chronic Recurrent Multifocal Osteomyelitis","volume":"8","author":"Jurik","year":"2004","journal-title":"Semin. Musculoskelet. Radiol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.crad.2011.08.014","article-title":"SAPHO: What radiologists should know","volume":"67","author":"DePasquale","year":"2012","journal-title":"Clin. Radiol."},{"key":"ref_73","doi-asserted-by":"crossref","unstructured":"Andronikou, S., Kraft, J.K., Offiah, A.C., Jones, J., Douis, H., Thyagarajan, M., Barrera, C.A., Zouvani, A., and Ramanan, A.V. (2020). Whole-body MRI in the diagnosis of paediatric CNO\/CRMO. Rheumatology.","DOI":"10.1093\/rheumatology\/keaa303"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s00223-018-0495-0","article-title":"Chronic Non-bacterial Osteomyelitis: A Review","volume":"104","author":"Buch","year":"2019","journal-title":"Calcif. Tissue Int."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.autrev.2018.11.007","article-title":"Amplifying the concept of psoriatic arthritis: The role of autoimmunity in systemic psoriatic disease","volume":"18","author":"Chimenti","year":"2019","journal-title":"Autoimmun. Rev."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s11604-020-00953-1","article-title":"Imaging features in patients with SAPHO\/CRMO: A pictorial review","volume":"38","author":"Himuro","year":"2020","journal-title":"Jpn. J. Radiol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/12\/4074\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:46:19Z","timestamp":1760179579000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/9\/12\/4074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,17]]},"references-count":76,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12]]}},"alternative-id":["jcm9124074"],"URL":"https:\/\/doi.org\/10.3390\/jcm9124074","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2020,12,17]]}}}