{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:45:51Z","timestamp":1789188351242,"version":"build-2803163510"},"reference-count":41,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>Dental pulp vitality preservation in dental caries treatment is a major goal in odontotherapy. The main objective of this study was to compare dental pulp tissue responses to vital therapies in deep carious lesions, using different calcium-based materials. An ambispective study was conducted on 47 patients. Ninety-five teeth with deep carious lesions were treated. Among them, 25 (26.32%) were diagnosed with pulpal exposures and treated by direct pulp capping. Indirect pulp capping was applied when pulp exposure was absent (n = 70; 73.68%). Fifty teeth (52.63%) were treated with TheraCal LC (prospective study), 31 teeth (32.63%) with Calcimol LC, and 14 teeth (14.74%) with Life Kerr AC (retrospective study). The results show that the survival rate for dental pulp was 100% for Life Kerr AC, 92% for TheraCal LC, and 83.87% for Calcimol LC, without significant differences. Apparently, self-setting calcium hydroxide material provided better dental pulp response than the two light-cured materials, regardless of their composition, that is, either calcium -hydroxide or calcium silicate-based. We will need a significant number of long-term clinical studies with the highest levels of evidence to determine the most adequate biomaterials for vital pulp therapies.<\/jats:p>","DOI":"10.3390\/jfb13020051","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T07:08:58Z","timestamp":1651475338000},"page":"51","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Dental Pulp Response to Different Types of Calcium-Based Materials Applied in Deep Carious Lesion Treatment\u2014A Clinical Study"],"prefix":"10.3390","volume":"13","author":[{"given":"Antoanela","family":"Covaci","sequence":"first","affiliation":[{"name":"Department of Embryology, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"Department of Dental Medicine, Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati, 800010 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucian Toma","family":"Ciocan","sequence":"additional","affiliation":[{"name":"Department of Prosthetics Technology and Dental Materials, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 010221 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0762-1016","authenticated-orcid":false,"given":"Bogdan","family":"G\u0103lbina\u0219u","sequence":"additional","affiliation":[{"name":"Department of Prosthetics Technology and Dental Materials, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 010221 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirela Veronica","family":"Bucur","sequence":"additional","affiliation":[{"name":"Department of Prosthetics Technology and Dental Materials, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 010221 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina","family":"Matei","sequence":"additional","affiliation":[{"name":"Department of Dental Medicine, Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati, 800010 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2915-5124","authenticated-orcid":false,"given":"Andreea Cristiana","family":"Didilescu","sequence":"additional","affiliation":[{"name":"Department of Embryology, Faculty of Dental Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"856087","DOI":"10.1155\/2010\/856087","article-title":"Vital pulp therapy-current progress of dental pulp regeneration and revascularization","volume":"2010","author":"Zhang","year":"2010","journal-title":"Int. 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