{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T01:15:51Z","timestamp":1778202951680,"version":"3.51.4"},"reference-count":127,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Sichuan Science and Technology Program","award":["2021YFS0085"],"award-info":[{"award-number":["2021YFS0085"]}]},{"name":"Sichuan Science and Technology Program","award":["2022NSFSC0743"],"award-info":[{"award-number":["2022NSFSC0743"]}]},{"name":"Sichuan Science and Technology Program","award":["RD-02-202107"],"award-info":[{"award-number":["RD-02-202107"]}]},{"name":"Sichuan Science and Technology Program","award":["RD-02-202114"],"award-info":[{"award-number":["RD-02-202114"]}]},{"name":"Sichuan Science and Technology Program","award":["No. RCDWJS2021-13"],"award-info":[{"award-number":["No. RCDWJS2021-13"]}]},{"name":"Sichuan Science and Technology Program","award":["2021YFS0085"],"award-info":[{"award-number":["2021YFS0085"]}]},{"name":"Sichuan Science and Technology Program","award":["2022NSFSC0743"],"award-info":[{"award-number":["2022NSFSC0743"]}]},{"name":"Sichuan Science and Technology Program","award":["RD-02-202107"],"award-info":[{"award-number":["RD-02-202107"]}]},{"name":"Sichuan Science and Technology Program","award":["RD-02-202114"],"award-info":[{"award-number":["RD-02-202114"]}]},{"name":"Sichuan Science and Technology Program","award":["No. RCDWJS2021-13"],"award-info":[{"award-number":["No. RCDWJS2021-13"]}]},{"name":"Research and Development Program of West China Hospital of Stomatology, Sichuan University","award":["2021YFS0085"],"award-info":[{"award-number":["2021YFS0085"]}]},{"name":"Research and Development Program of West China Hospital of Stomatology, Sichuan University","award":["2022NSFSC0743"],"award-info":[{"award-number":["2022NSFSC0743"]}]},{"name":"Research and Development Program of West China Hospital of Stomatology, Sichuan University","award":["RD-02-202107"],"award-info":[{"award-number":["RD-02-202107"]}]},{"name":"Research and Development Program of West China Hospital of Stomatology, Sichuan University","award":["RD-02-202114"],"award-info":[{"award-number":["RD-02-202114"]}]},{"name":"Research and Development Program of West China Hospital of Stomatology, Sichuan University","award":["No. RCDWJS2021-13"],"award-info":[{"award-number":["No. RCDWJS2021-13"]}]},{"name":"West China School\/Hospital of Stomatology, Sichuan University","award":["2021YFS0085"],"award-info":[{"award-number":["2021YFS0085"]}]},{"name":"West China School\/Hospital of Stomatology, Sichuan University","award":["2022NSFSC0743"],"award-info":[{"award-number":["2022NSFSC0743"]}]},{"name":"West China School\/Hospital of Stomatology, Sichuan University","award":["RD-02-202107"],"award-info":[{"award-number":["RD-02-202107"]}]},{"name":"West China School\/Hospital of Stomatology, Sichuan University","award":["RD-02-202114"],"award-info":[{"award-number":["RD-02-202114"]}]},{"name":"West China School\/Hospital of Stomatology, Sichuan University","award":["No. RCDWJS2021-13"],"award-info":[{"award-number":["No. RCDWJS2021-13"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>An oronasal fistula (ONF) is an abnormal structure between the oral and nasal cavities, which is a common complication of cleft palate repair due to the failure of wound healing. When some patients with ONF are unsuitable for secondary surgical repair, the obturator treatment becomes a potential method. The objectives of the obturator treatment should be summarized as filling the ONF comfortably and cosmetically restoring the dentition with partial function. The anatomy of patients with cleft palate is complex, which may lead to a more complex structure of the ONF. Thus, the manufacturing process of the obturator for these patients is more difficult. For performing the design and fabrication process rapidly and precisely, digital techniques can help, but limitations still exist. In this review, literature searches were conducted through Medline via PubMed, Wiley Online Library, Science Direct, and Web of Science, and 122 articles were selected. The purpose of this review was to introduce the development of the obturator for treating patients with ONF after cleft palate repair, from the initial achievement of the obstruction of the ONF to later problems such as fixation, velopharyngeal insufficiency, and infection, as well as the application of digital technologies in obturator manufacturing.<\/jats:p>","DOI":"10.3390\/jfb13040251","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T03:57:44Z","timestamp":1668743864000},"page":"251","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Obturator Manufacturing for Oronasal Fistula after Cleft Palate Repair: A Review from Handicraft to the Application of Digital Techniques"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7376-3322","authenticated-orcid":false,"given":"Jiali","family":"Chen","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renjie","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Eastern Clinic, West China Hospital of Stomatology, Sichuan University, Chengdu 610051, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0744-3050","authenticated-orcid":false,"given":"Yichen","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6805-0157","authenticated-orcid":false,"given":"Hanyao","family":"Huang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,17]]},"reference":[{"key":"ref_1","first-page":"1499","article-title":"MSX1 gene in the etiology orofacial deformities","volume":"69","year":"2015","journal-title":"Postep. 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