{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:55:06Z","timestamp":1785855306072,"version":"3.56.0"},"reference-count":42,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T00:00:00Z","timestamp":1687651200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["20-19-00120"],"award-info":[{"award-number":["20-19-00120"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["20-52-26020"],"award-info":[{"award-number":["20-52-26020"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research RFBR","doi-asserted-by":"publisher","award":["20-19-00120"],"award-info":[{"award-number":["20-19-00120"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research RFBR","doi-asserted-by":"publisher","award":["20-52-26020"],"award-info":[{"award-number":["20-52-26020"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>The objective of this research was to develop an environment-friendly and scalable method for the production of self-sanitizing electrospun nanofibers. This was achieved by immobilizing silver nanoparticles (Ag NPs) onto plasma-treated surfaces of biodegradable polycaprolactone (PCL) nanofibers. The plasma deposited polymer layer containing carboxyl groups played a critical role in providing a uniform distribution of Ag NPs on the nanofiber surface. Ag ions were absorbed by electrostatic interaction and then reduced under the action of UV-light. The concentration and release of Ag ions were analyzed using the EDXS\/XPS and ICP AES methods, respectively. Although high levels of Ag ions were detected after 3 h of immersion in water, the material retained a sufficient amount of silver nanoparticles on the surface (~2.3 vs. 3.5 at.% as determined by XPS), and the release rate subsequently decreased over the next 69 h. The antipathogenic properties of PCL-Ag were tested against gram-negative and gram-positive bacteria, fungi, and biofilm formation. The results showed that the PCL-Ag nanofibers exhibit significant antimicrobial activity against a wide range of microorganisms, including those that cause human infections. The incorporation of Ag NPs into PCL nanofibers resulted in a self-sanitizing material that can be used in variety of applications, including wound dressings, water treatment, and air filtration. The development of a simple, scalable, and environmentally friendly method for the fabrication of these nanofibers is essential to ensure their widespread use in various industries. The ability to control the concentration and release rate of Ag ions in the PCL nanofibers will be critical to optimize their efficacy while minimizing their potential toxicity to human cells and the environment.<\/jats:p>","DOI":"10.3390\/jfb14070336","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T03:14:56Z","timestamp":1687749296000},"page":"336","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Self-Sanitizing Polycaprolactone Electrospun Nanofiber Membrane with Ag Nanoparticles"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2581-0803","authenticated-orcid":false,"given":"Elizaveta S.","family":"Permyakova","sequence":"first","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4517-1682","authenticated-orcid":false,"given":"Anton","family":"Manakhov","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"},{"name":"Research Institute of Clinical and Experimental Lymphology\u2014Branch of the ICG SB RAS, 2 Timakova st., Novosibirsk 630060, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1635-4746","authenticated-orcid":false,"given":"Philipp V.","family":"Kiryukhantsev-Korneev","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2597-6611","authenticated-orcid":false,"given":"Anton S.","family":"Konopatsky","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulia A.","family":"Makarets","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8990-9784","authenticated-orcid":false,"given":"Kristina Yu.","family":"Kotyakova","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana Yu.","family":"Filippovich","sequence":"additional","affiliation":[{"name":"Bach Institute of Biochemistry, Moscow 115419, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey G.","family":"Ignatov","sequence":"additional","affiliation":[{"name":"State Research Center for Applied Microbiology and Biotechnology, Obolensk 142279, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasiya O.","family":"Solovieva","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical and Experimental Lymphology\u2014Branch of the ICG SB RAS, 2 Timakova st., Novosibirsk 630060, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7304-2461","authenticated-orcid":false,"given":"Dmitry V.","family":"Shtansky","sequence":"additional","affiliation":[{"name":"National University of Science and Technology \u201cMISIS\u201d, Moscow 119049, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"102435","DOI":"10.1016\/j.cis.2021.102435","article-title":"Face Masks against COVID-19: Standards, Efficacy, Testing and Decontamination Methods","volume":"292","author":"Ju","year":"2021","journal-title":"Adv. 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