{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:55:13Z","timestamp":1789581313823,"version":"build-2803163510"},"reference-count":59,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Foundation of Beijing Municipality","award":["7232213"],"award-info":[{"award-number":["7232213"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>In recent years, the use of zinc (Zn) alloys as degradable metal materials has attracted considerable attention in the field of biomedical bone implant materials. This study investigates the fabrication of porous scaffolds using a Zn-1Mg-0.1Sr alloy through a three-dimensional (3D) printing technique, selective laser melting (SLM). The results showed that the porous Zn-1Mg-0.1Sr alloy scaffold featured a microporous structure and exhibited a compressive strength (CS) of 33.71 \u00b1 2.51 MPa, a yield strength (YS) of 27.88 \u00b1 1.58 MPa, and an elastic modulus (E) of 2.3 \u00b1 0.8 GPa. During the immersion experiments, the immersion solution showed a concentration of 2.14 \u00b1 0.82 mg\/L for Zn2+ and 0.34 \u00b1 0.14 mg\/L for Sr2+, with an average pH of 7.61 \u00b1 0.09. The porous Zn-1Mg-0.1Sr alloy demonstrated a weight loss of 12.82 \u00b1 0.55% and a corrosion degradation rate of 0.36 \u00b1 0.01 mm\/year in 14 days. The Cell Counting Kit-8 (CCK-8) assay was used to check the viability of the cells. The results showed that the 10% and 20% extracts significantly increased the activity of osteoblast precursor cells (MC3T3-E1), with a cytotoxicity grade of 0, which indicates safety and non-toxicity. In summary, the porous Zn-1Mg-0.1Sr alloy scaffold exhibits outstanding mechanical properties, an appropriate degradation rate, and favorable biosafety, making it an ideal candidate for degradable metal bone implants.<\/jats:p>","DOI":"10.3390\/jfb15040109","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T06:21:12Z","timestamp":1713421272000},"page":"109","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["3D Printing of a Porous Zn-1Mg-0.1Sr Alloy Scaffold: A Study on Mechanical Properties, Degradability, and Biosafety"],"prefix":"10.3390","volume":"15","author":[{"given":"Xiangyu","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinguang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiazheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China"},{"name":"Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00590-020-02765-5","article-title":"Allogeneic umbilical cord-derived mesenchymal stem cells for treating critical-sized bone defects: A translational study","volume":"31","author":"Dilogo","year":"2021","journal-title":"Eur. 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