{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:39:25Z","timestamp":1759365565383,"version":"build-2065373602"},"reference-count":59,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.mdpi.com"],"crossmark-restriction":true},"short-container-title":["JFB"],"abstract":"<jats:p>Background: The aim of this bibliometric study was to evaluate publication trends in the most frequently cited clinical trials on the treatment of gingival recession, taking into account the augmentation materials used. Methods: A Web of Science search was performed among articles published by 30 September 2024. Two independent reviewers evaluated year of publication, journal, authorship country of authors, collaborative relationship, keywords, and the main domains. Results: The top one hundred most-cited clinical trials were published in the span of 26 years from 1993 to 2019, and the total citation counts varied from 44 to 284 (83.69 citations per paper). There was correlation between the time of publication and the number of citations. The articles were authored by 333 researchers representing twenty-two countries. Italy contributed the highest number of articles (n = 36), followed by the USA (n = 28) and Brazil (n = 17). International collaborations were predominantly observed between Italy, the USA, and Switzerland. The type of graft was the most cited field of research (34), followed by guided tissue regeneration (17) and enamel matrix derivative (13). Conclusions: The country that produced the highest number publications among the 100 most-cited clinical trials on gingival recession treatment was Italy. The use of connective tissue graft (CTG) and coronally advanced flap (CAF) was the most prominent trend. Future work should combine bibliometric mapping with critical quality appraisal and explore whether citation trends align with best available evidence.<\/jats:p>","DOI":"10.3390\/jfb16100364","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T07:58:13Z","timestamp":1759305493000},"page":"364","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bibliometric Analysis of the 100 Most-Cited Clinical Trials on Gingival Recession Treatment: Trends in Flap Design, Biomaterials, and Global Contributions"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3918-4332","authenticated-orcid":false,"given":"Bart\u0142omiej","family":"G\u00f3rski","sequence":"first","affiliation":[{"name":"Department of Periodontal and Oral Mucosa Diseases, Medical University of Warsaw, 02-097 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5042-5985","authenticated-orcid":false,"given":"Kacper","family":"Nijakowski","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilham","family":"Mounssif","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, Bologna University, 40126 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Stefanini","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, Bologna University, 40126 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7473-3552","authenticated-orcid":false,"given":"Anna","family":"Skurska","sequence":"additional","affiliation":[{"name":"Department of Integrated Dentistry, Medical University of Bialystok, 15-276 Bialystok, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1902\/annals.1996.1.1.671","article-title":"Mucogingival therapy","volume":"1","year":"1996","journal-title":"Ann. Periodontol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1902\/jop.1999.70.1.30","article-title":"Gingival recession, gingival bleeding, and dental calculus in adults 30 years of age and older in the United States, 1988\u20131994","volume":"70","author":"Albandar","year":"1999","journal-title":"J. Periodontol."},{"key":"ref_3","first-page":"S219","article-title":"Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Jepsen","year":"2017","journal-title":"J. Clin. Periodontol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1111\/j.1600-051X.2011.01732.x","article-title":"The interproximal clinical attachment level to classify gingival recessions and predict root coverage outcomes: An explorative and reliability study","volume":"38","author":"Cairo","year":"2011","journal-title":"J. Clin. Periodontol."},{"key":"ref_5","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller","year":"1985","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/prd.12059","article-title":"Periodontal plastic surgery","volume":"68","author":"Zucchelli","year":"2015","journal-title":"Periodontol. 2000"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1002\/JPER.22-0167","article-title":"Does the subepithelial connective tissue graft in conjunction with a coronally advanced flap remain as the gold standard therapy for the treatment of single gingival recession defects? A systematic review and network meta-analysis","volume":"93","author":"Chambrone","year":"2022","journal-title":"J. Periodontol."},{"key":"ref_8","first-page":"CD007161","article-title":"Root coverage procedures for treating localised and multiple recession-type defects","volume":"10","author":"Chambrone","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1002\/JPER.18-0066","article-title":"Efficacy of tunnel technique in the treatment of localized and multiple gingival recessions: A systematic review and meta-analysis","volume":"89","author":"Tavelli","year":"2018","journal-title":"J. Periodontol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1002\/asi.22708","article-title":"The Leiden ranking 2011\/2012: Data collection, indicators, and interpretation","volume":"63","author":"Waltman","year":"2012","journal-title":"J. Am. Soc. Inf. Sci. Technol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s11192-013-1147-9","article-title":"The life sciences in German\u2013Chinese cooperation: An institutional-level co-publication analysis","volume":"98","author":"Barth","year":"2014","journal-title":"Scientometrics"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s11192-015-1645-z","article-title":"The bibliometric analysis of scholarly production: How great is the impact?","volume":"105","author":"Ellegaard","year":"2015","journal-title":"Scientometrics"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jbusres.2021.04.070","article-title":"How to conduct a bibliometric analysis: An overview and guidelines","volume":"133","author":"Donthu","year":"2021","journal-title":"J. Bus. Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1111\/j.1600-051X.2010.01550.x","article-title":"Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: A comparative randomized-controlled clinical trial","volume":"37","author":"Zucchelli","year":"2010","journal-title":"J. Clin. Periodontol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1902\/jop.2009.080253","article-title":"Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: A 6-month study","volume":"80","author":"Aroca","year":"2009","journal-title":"J. Periodontol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1902\/jop.2000.71.2.188","article-title":"Coronally advanced flap procedure for root coverage. Flap with tension versus flap without tension: A randomized controlled clinical study","volume":"71","author":"Pagliaro","year":"2000","journal-title":"J. Periodontol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1902\/jop.2010.090698","article-title":"Xenogeneic collagen matrix with coronally advanced flap compared to connective tissue with coronally advanced flap for the treatment of dehiscence-type recession defects","volume":"81","author":"McGuire","year":"2010","journal-title":"J. Periodontol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1902\/jop.2001.72.8.998","article-title":"Clinical evaluation of acellular allograft dermis for the treatment of human gingival recession","volume":"72","author":"Yukna","year":"2001","journal-title":"J. Periodontol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1902\/jop.2009.090041","article-title":"Coronally advanced flap with and without vertical releasing incisions for the treatment of multiple gingival recessions: A comparative controlled randomized clinical trial","volume":"80","author":"Zucchelli","year":"2009","journal-title":"J. Periodontol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1600-051X.2008.01346.x","article-title":"Does placement of a connective tissue graft improve the outcomes of coronally advanced flap for coverage of single gingival recessions in upper anterior teeth? A multi-centre, randomized, double-blind, clinical trial","volume":"36","author":"Cortellini","year":"2009","journal-title":"J. Clin. Periodontol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1600-051X.2009.01492.x","article-title":"Treatment of class III multiple gingival recessions: A randomized-clinical trial","volume":"37","author":"Aroca","year":"2010","journal-title":"J. Clin. Periodontol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/jcpe.12112","article-title":"Treatment of multiple adjacent Miller class I and II gingival recessions with a Modified Coronally Advanced Tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: A randomized, controlled clinical trial","volume":"40","author":"Aroca","year":"2013","journal-title":"J. Clin. Periodontol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1034\/j.1600-051X.2003.00397.x","article-title":"Bilaminar techniques for the treatment of recession-type defects. A comparative clinical study","volume":"30","author":"Zucchelli","year":"2003","journal-title":"J. Clin. Periodontol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1600-051X.2010.01559.x","article-title":"Coronally advanced flap versus connective tissue graft in the treatment of multiple gingival recessions: A split-mouth study with a 5-year follow-up","volume":"37","author":"Cairo","year":"2010","journal-title":"J. Clin. Periodontol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1600-051X.2005.00660.x","article-title":"Coverage of localized gingival recessions: Comparison of micro- and macrosurgical techniques","volume":"32","author":"Burkhardt","year":"2005","journal-title":"J. Clin. Periodontol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1902\/jop.1994.65.10.929","article-title":"Subepithelial connective tissue grafts in the treatment of gingival recessions. A comparative study of two procedures","volume":"65","author":"Bouchard","year":"1994","journal-title":"J. Periodontol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/jcpe.12019","article-title":"Treatment of gingival recession defects with a coronally advanced flap and a xenogeneic collagen matrix: A multicenter randomized clinical trial","volume":"40","author":"Jepsen","year":"2013","journal-title":"J. Clin. Periodontol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1902\/jop.2004.75.3.413","article-title":"Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft","volume":"75","author":"Joly","year":"2004","journal-title":"J. Periodontol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1902\/jop.2005.76.2.178","article-title":"Histologic evaluation of autogenous connective tissue and acellular dermal matrix grafts in humans","volume":"76","author":"Cummings","year":"2005","journal-title":"J. Periodontol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1902\/jop.2003.74.8.1110","article-title":"Evaluation of human recession defects treated with coronally advanced flaps and either enamel matrix derivative or connective tissue. Part 1: Comparison of clinical parameters","volume":"74","author":"McGuire","year":"2003","journal-title":"J. Periodontol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1902\/jop.1993.64.4.315","article-title":"Thick free gingival and connective tissue autografts for root coverage","volume":"64","author":"Jahnke","year":"1993","journal-title":"J. Periodontol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1902\/jop.2002.73.11.1299","article-title":"Subpedicle acellular dermal matrix graft and autogenous connective tissue graft in the treatment of gingival recessions: A comparative 1-year clinical study","volume":"73","author":"Paolantonio","year":"2002","journal-title":"J. Periodontol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1902\/jop.1996.67.1.7","article-title":"Comparative study of a bioresorbable and a non-resorbable membrane in the treatment of human buccal gingival recessions","volume":"67","author":"Roccuzzo","year":"1996","journal-title":"J. Periodontol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1902\/jop.1997.68.8.779","article-title":"A comparative study of root coverage obtained with guided tissue regeneration utilizing a bioabsorbable membrane versus the connective tissue with partial-thickness double pedicle graft","volume":"68","author":"Harris","year":"1997","journal-title":"J. Periodontol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1902\/jop.1998.69.2.138","article-title":"Mucogingival versus guided tissue regeneration procedures in the treatment of deep recession type defects","volume":"69","author":"Zucchelli","year":"1998","journal-title":"J. Periodontol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1902\/jop.2002.73.12.1405","article-title":"Root coverage of advanced gingival recession: A comparative study between acellular dermal matrix allograft and subepithelial connective tissue grafts","volume":"73","author":"Tal","year":"2002","journal-title":"J. Periodontol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1902\/jop.2011.110215","article-title":"Treatment of gingival recession defects using coronally advanced flap with a porcine collagen matrix compared to coronally advanced flap with connective tissue graft: A randomized controlled clinical trial","volume":"83","author":"Cardaropoli","year":"2012","journal-title":"J. Periodontol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/jcpe.12834","article-title":"Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: Randomized trial assessing non-inferiority in root coverage and superiority in oral health-related quality of life","volume":"45","author":"Tonetti","year":"2018","journal-title":"J. Clin. Periodontol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/cid.13177","article-title":"Peri-implantitis: A bibliometric network analysis of top 100 most-cited research articles","volume":"25","author":"Sabri","year":"2023","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"167","DOI":"10.4103\/jispcd.jispcd_8_24","article-title":"Bibliometric analysis of the top 100 cited articles in regenerative periodontics surgery: Insights and trends","volume":"27","author":"Alqahtani","year":"2024","journal-title":"J. Int. Soc. Prev. Community Dent."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/prd.12376","article-title":"A bibliometric analysis of periodontology","volume":"85","author":"Ahmad","year":"2021","journal-title":"Periodontol. 2000"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.2217\/rme-2019-0019","article-title":"Periodontal regeneration: A bibliometric analysis of the most influential studies","volume":"14","author":"Shaikh","year":"2019","journal-title":"Regen. Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2334\/josnusd.20-0565","article-title":"A bibliometric study of the top cited papers related to periodontal regeneration","volume":"29","author":"Liu","year":"2021","journal-title":"J. Oral Sci."},{"key":"ref_44","first-page":"e45734","article-title":"Bibliometric analysis of the 100 most-cited articles on periodontics in the Arab World","volume":"15","author":"Aljabbary","year":"2023","journal-title":"Cureus"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Asiri, F.Y., Kruger, E., and Tennant, M. (2021). The top 100 most cited articles published in dentistry: 2020 update. Healthcare, 9.","DOI":"10.20944\/preprints202102.0022.v1"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1600-051X.2007.01060.x","article-title":"Citation classics in periodontology: A controlled study","volume":"34","author":"Nieri","year":"2007","journal-title":"J. Clin. Periodontol."},{"key":"ref_47","first-page":"e112","article-title":"Bibliometric analysis of research on regenerative periodontal surgery during the last 30 years","volume":"1","year":"2012","journal-title":"J. Clin. Exp. Dent."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1111\/clr.14152","article-title":"Bibliometric analysis of the 100 most cited articles on bone grafting in dentistry","volume":"34","author":"Rocha","year":"2023","journal-title":"Clin. Oral Implants Res."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.11607\/jomi.5104","article-title":"The 300 most-cited articles in implant dentistry","volume":"32","author":"Esparza","year":"2017","journal-title":"Int. J. Oral Maxillofac. Implants."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1902\/jop.2009.080502","article-title":"Growth factor-mediated treatment of recession defects: A randomized controlled trial and histologic and microcomputed tomography examination","volume":"80","author":"McGuire","year":"2009","journal-title":"J. Periodontol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1034\/j.1600-0765.2001.360601.x","article-title":"Gingival recession defects and guided tissue regeneration: A review","volume":"36","year":"2001","journal-title":"J. Periodontal Res."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/jcpe.13346","article-title":"Aesthetic- and patient-related outcomes following root coverage procedures: A systematic review and network meta-analysis","volume":"47","author":"Cairo","year":"2020","journal-title":"J. Clin. Periodontol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/SAP.0000000000000585","article-title":"What effect does self-citation have on bibliometric measures in academic plastic surgery?","volume":"77","author":"Swanson","year":"2016","journal-title":"Ann. Plast. Surg."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jclinepi.2019.03.008","article-title":"Improving the content validity of the mixed methods appraisal tool: A modified e-Delphi study","volume":"111","author":"Hong","year":"2019","journal-title":"J. Clin. Epidemiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3346\/jkms.2017.32.2.173","article-title":"The journal impact factor: Moving toward an alternative and combined scientometric approach","volume":"32","author":"Gasparyan","year":"2017","journal-title":"J. Korean Med. Sci."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1136\/jim-2019-001009","article-title":"Journal impact factor: A bumpy ride in an open space","volume":"68","author":"Kaldas","year":"2020","journal-title":"J. Investig. Med."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s11192-012-0805-7","article-title":"On the relationship between citations of publication output and Hirsch index h of authors: Conceptualization of tapered Hirsch index hT, circular citation area radius R and citation acceleration a","volume":"93","author":"Sangwal","year":"2012","journal-title":"Scientometrics"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/embor.2008.233","article-title":"The state of h index research. Is the h index the ideal way to measure research performance?","volume":"10","author":"Bornmann","year":"2009","journal-title":"EMBO Rep."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Hutchins, B.I., Yuan, X., Anderson, J.M., and Santangelo, G.M. (2016). Relative citation ratio (RCR): A new metric that uses citation rates to measure influence at the article level. PLoS Biol., 14.","DOI":"10.1371\/journal.pbio.1002541"}],"container-title":["Journal of Functional Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-4983\/16\/10\/364\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T08:34:02Z","timestamp":1759307642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-4983\/16\/10\/364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,1]]},"references-count":59,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["jfb16100364"],"URL":"https:\/\/doi.org\/10.3390\/jfb16100364","relation":{},"ISSN":["2079-4983"],"issn-type":[{"value":"2079-4983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,1]]}}}