{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:54:27Z","timestamp":1790175267527,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>Modified chitosan (Cs) derivatives were synthesized and evaluated as potential antibacterial and antiviral coatings of medical protective equipment (facial masks, gloves, \u2026). Quaternized chitosan (HTCC) and chitosan\u2013silver nanocomposites (Ag\/Cs) were successfully prepared, with structural characterization confirming efficient quaternization and uniform incorporation of silver nanoparticles. Antibacterial testing revealed that HTCC exhibited concentration-dependent activity, while Ag\/Cs showed strong broad-spectrum antibacterial effects and enhanced thermal stability. Antiviral assays against SARS-CoV-2 demonstrated significant viral inhibition for HTCC6 and Ag\/Cs at non-cytotoxic concentrations (6 mg\/mL), highlighting the role of cationic charge and nanoparticle inclusion in antiviral efficacy. These findings indicate that the developed chitosan derivatives are promising candidates for sustainable functional coatings on medical devices, offering potential applications in infection prevention.<\/jats:p>","DOI":"10.3390\/jfb17040193","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:48:12Z","timestamp":1776412092000},"page":"193","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Synthesis and Characterization of Modified Chitosan Materials with Assessment of Their Antibacterial and Antiviral Activities"],"prefix":"10.3390","volume":"17","author":[{"given":"Dhouha","family":"Bouzir","sequence":"first","affiliation":[{"name":"Textile Materials and Processes Laboratory (MPTex), National Engineering School of Monastir (ENIM), University of Monastir, Monastir 5019, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4242-6512","authenticated-orcid":false,"given":"Adel","family":"Elamri","sequence":"additional","affiliation":[{"name":"Textile Materials and Processes Laboratory (MPTex), National Engineering School of Monastir (ENIM), University of Monastir, Monastir 5019, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khmais","family":"Zdiri","sequence":"additional","affiliation":[{"name":"Textile Science and TechnologyResearch Center in Monastir (CRSTTM), University of Monastir, Monastir 5019, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Hamdaoui","sequence":"additional","affiliation":[{"name":"Textile Materials and Processes Laboratory (MPTex), National Engineering School of Monastir (ENIM), University of Monastir, Monastir 5019, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Delaite","sequence":"additional","affiliation":[{"name":"LPIM (EA 4567), ENSCMu, University of Haute Alsace (UHA), 68093 Mulhouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelaziz","family":"Lallam","sequence":"additional","affiliation":[{"name":"LPMT (UR 4365), ENSISA, University of Haute-Alsace (UHA), 68093 Mulhouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4693-2570","authenticated-orcid":false,"given":"Omar Anis","family":"Harzallah","sequence":"additional","affiliation":[{"name":"LPMT (UR 4365), ENSISA, University of Haute-Alsace (UHA), 68093 Mulhouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101480","DOI":"10.1016\/j.cocis.2021.101480","article-title":"Recent Breakthroughs of Antibacterial and Antiviral Protective Polymeric Materials during COVID-19 Pandemic and after Pandemic: Coating, Packaging, and Textile Applications","volume":"55","author":"Mallakpour","year":"2021","journal-title":"Curr. 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