{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:02:49Z","timestamp":1780722169044,"version":"3.54.1"},"reference-count":102,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFB"],"abstract":"<jats:p>The aim of this study was to evaluate the influence of artificial saliva ageing and cyclic hydrothermal loading on the mechanical properties of dental composite materials. Two commercial composites (Filtek Z550 and Filtek Ultimate Flow) and two experimental materials representing flow-type and hybrid composites were investigated. SENB specimens were prepared in accordance with ASTM E399, together with flat specimens intended for impact strength testing using the Dynstat method. All samples were aged in artificial saliva for approximately one month at 37 \u00b1 1 \u00b0C, and subsequently, half of the specimens were subjected to thermocycling in the temperature range of 10\u201365 \u00b0C for 10,000 cycles. Static mechanical tests, including three-point bending (TFS), biaxial flexural strength (BFS), and compression strength (CS), were performed before and after thermocycling. In addition, impact strength and fracture toughness expressed by the stress intensity factor KIC were determined. The results were analyzed in terms of the residual work of fracture (WOF), while the durability of the materials was evaluated using Weibull distribution parameters. The experimental analysis was complemented by SEM observations of the microstructure. The obtained results demonstrated a pronounced deterioration of mechanical properties after hydrothermal loading. The average impact strength after artificial saliva ageing reached 11.69 J\/mm2 for Filtek Z550, 11.57 J\/mm2 for Ex-hyb(P), 16.39 J\/mm2 for Filtek Ultimate Flow, and 10.27 J\/mm2 for Ex-flow(P), whereas after thermocycling, these values decreased to 5.38 J\/mm2, 8.86 J\/mm2, 4.55 J\/mm2, and 4.39 J\/mm2, respectively. A similar trend was observed for the fracture toughness parameter KIC, which decreased considerably after thermocycling for all investigated materials. The analysis of the residual work of fracture revealed the influence of thermocycling on the energy-related parameters of the composites. In the case of TFS, the average WOF decreased, among others, from 13.65\u00b710\u22123 J to 1.90\u00b710\u22123 J for Filtek Ultimate Flow and from 4.76\u00b710\u22123 J to 2.37\u00b710\u22123 J for Filtek Z550. For BFS, a noticeable decrease in WOF was also observed, particularly for Ex-flow(P) and Filtek Ultimate Flow. In the compression tests (CS), the changes were less unambiguous, and some materials exhibited an increase in WOF after thermocycling. Furthermore, changes in the scale and shape parameters of the Weibull distribution were identified, indicating degradation of composite durability under hydrothermal loading. The results confirmed that cyclic hydrothermal loading exerts a greater influence on impact strength and fracture toughness than on static flexural strength. While all investigated materials exhibited degradation, the extent of changes was material-dependent, and compression behaviour showed non-uniform responses. Weibull analysis confirmed reduced reliability and increased heterogeneity of the composites after ageing, indicating that hydrothermal fatigue is a dominant factor governing long-term mechanical deterioration of dental resin-based composites.<\/jats:p>","DOI":"10.3390\/jfb17060276","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:45:08Z","timestamp":1780404308000},"page":"276","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Influence of Ageing and Hydrothermal Fatigue (Thermocycling) on Degradation and Fracture Toughness of Light-Cured and Hybrid Resin-Based Nanocomposites (RBCs)"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-3515","authenticated-orcid":false,"given":"Daniel","family":"Pieniak","sequence":"first","affiliation":[{"name":"Faculty of Safety Engineering and Civil Protection, Fire University, 52\/54 S\u0142owackiego Street, 01-629 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-5638","authenticated-orcid":false,"given":"Agata Maria","family":"Niewczas","sequence":"additional","affiliation":[{"name":"Faculty of Medical Dentistry, Medical University of Lublin, 19 Chod\u017aki St., 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0303-1748","authenticated-orcid":false,"given":"Agata","family":"Walczak","sequence":"additional","affiliation":[{"name":"Faculty of Safety Engineering and Civil Protection, Fire University, 52\/54 S\u0142owackiego Street, 01-629 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2656-3800","authenticated-orcid":false,"given":"Jaros\u0142aw","family":"Selech","sequence":"additional","affiliation":[{"name":"Faculty of Civil and Transport Engineering, Institute of Machines and Motor Vehicles, Poznan University of Technology, 3 Piotrowo St., 60-965 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5027-7484","authenticated-orcid":false,"given":"Dorota","family":"Czarnecka-Komorowska","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical Engineering, Poznan University of Technology, 3 Piotrowo St., 60-965 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6006-9470","authenticated-orcid":false,"given":"Jonas","family":"Matijo\u0161ius","sequence":"additional","affiliation":[{"name":"Mechanical Science Institute, Vilnius Gediminas Technical University, Plytin\u0117s Str. 25, 10105 Vilnius, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Yu, H., Yao, J., Du, Z., Guo, J., and Lei, W. (2024). Comparative evaluation of mechanical properties and color stability of dental resin composites for chairside provisional restorations. Polymers, 16.","DOI":"10.3390\/polym16142089"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Temizci, T., and Bozo\u011fullar\u0131, H.N. (2024). Effect of thermocycling on the mechanical properties of permanent composite-based CAD-CAM restorative materials produced by additive and subtractive manufacturing techniques. BMC Oral Health, 24.","DOI":"10.1186\/s12903-024-04016-z"},{"key":"ref_3","first-page":"18","article-title":"Effect of the structure and hydrothermal conditions on the strength of polymer-ceramic composites","volume":"121","author":"Walczak","year":"2023","journal-title":"J. Achiev. Mater. Manuf. Eng."},{"key":"ref_4","first-page":"9","article-title":"Phenomenological evaluation of fatigue cracking of dental restorations under conditions of cyclic mechanical loads","volume":"14","author":"Pieniak","year":"2012","journal-title":"Acta Bioeng. Biomech."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"113001","DOI":"10.1088\/0022-3727\/41\/11\/113001","article-title":"Tribology of dental materials: A review","volume":"41","author":"Zhou","year":"2008","journal-title":"J. Phys. D Appl. Phys."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jmbbm.2007.05.001","article-title":"Understanding the mechanical behaviour of human enamel from its structural and compositional characteristics","volume":"1","author":"He","year":"2008","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jdent.2010.02.003","article-title":"The effect of clinically relevant thermocycling on the flexural properties of endodontic post materials","volume":"38","author":"Stewardson","year":"2010","journal-title":"J. Dent."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.15517\/ijds.v21i2.36783","article-title":"Color change of different dual-cure resin cements after thermocycling","volume":"21","author":"Atay","year":"2019","journal-title":"Odovtos Int. J. Dent. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.fdj.2017.10.002","article-title":"Correlation of salivary characteristics with high risk of dental caries: A clinical investigation","volume":"4","author":"Khan","year":"2018","journal-title":"Future Dent. J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.msec.2015.05.004","article-title":"Effects of temperature change and beverage on mechanical and tribological properties of dental restorative composites","volume":"54","author":"Ayatollahi","year":"2015","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.dental.2003.11.008","article-title":"Effects of strain rate and temperature on the mechanical properties of resin composites","volume":"20","author":"Musanje","year":"2004","journal-title":"Dent. Mater."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Vallittu, P. (2013). Effects of particulate filler systems on the properties and performance of dental polymer composites. Non-Metallic Biomaterials for Tooth Repair and Replacement, Woodhead Publishing.","DOI":"10.1533\/9780857096432"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Krzyzak, A., Racinowski, D., Szczepaniak, R., and Kosicka, E. (2023). An assessment of the reliability of CFRP composites used in nodes of friction after impact of UV-A impacts and thermal shocks. Eksploat. Niezawodn., 25.","DOI":"10.17531\/ein\/174221"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.dental.2022.04.010","article-title":"Influence of thermal and thermomechanical stimuli on a molar tooth treated with resin-based restorative dental composites","volume":"38","author":"Babaei","year":"2022","journal-title":"Dent. Mater."},{"key":"ref_15","first-page":"259","article-title":"FDI World Dental Federation\u2014Clinical criteria for the evaluation of direct and indirect restorations: Update and clinical examples","volume":"12","author":"Hickel","year":"2010","journal-title":"J. Adhes. Dent."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dental.2022.11.009","article-title":"Longevity of composite restorations is definitely not only about materials","volume":"39","author":"Demarco","year":"2023","journal-title":"Dent. Mater."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Al-Ibrahim, I., Shono, N., Al-Saud, L., and Al-Nahedh, H. (2025). Five years of restorative resin-based composite advancements: A narrative review. BMC Oral Health, 25.","DOI":"10.1186\/s12903-025-05816-7"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.dental.2022.02.009","article-title":"Clinical performance of posterior resin composite restorations after up to 33 years","volume":"38","author":"Rodolfo","year":"2022","journal-title":"Dent. Mater."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1590\/1807-3107bor-2017.vol31.0056","article-title":"Should my composite restorations last forever? Why are they failing?","volume":"31","author":"Demarco","year":"2017","journal-title":"Braz. Oral Res."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Holban, A.-M., Farcasiu, C., Andrei, O.-C., Grumezescu, A.M., and Farcasiu, A.-T. (2021). Surface modification to modulate microbial biofilms\u2014Applications in dental medicine. Materials, 14.","DOI":"10.3390\/ma14226994"},{"key":"ref_21","first-page":"190","article-title":"Prevalence of secondary caries among different restorations","volume":"9","author":"Timothy","year":"2021","journal-title":"J. Res. Med. Dent. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4012\/dmj.2011-146","article-title":"Effect of air abrasion and thermocycling on resin adaptation and shear bond strength to dentin for an etch-and-rinse and self-etch resin adhesive","volume":"31","author":"Freeman","year":"2012","journal-title":"Dent. Mater. J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5395\/rde.2013.38.1.11","article-title":"The effect of clinical performance on the survival estimates of direct restorations","volume":"38","author":"Kim","year":"2013","journal-title":"Restor. Dent. Endod."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jdent.2009.03.014","article-title":"The effect of thermal cycling on metal-ceramic bond strength","volume":"37","author":"Fischer","year":"2009","journal-title":"J. Dent."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"\u0141agocka, R., Granat, M., Lewusz-Butkiewcz, K., Tomasik, M., and Lipski, M. (2023). The effect of thermal cycling on the surface roughness of nanohybrid and high-viscosity bulk-fill resin-based composites. Pomeranian J. Life Sci., 69.","DOI":"10.21164\/pomjlifesci.945"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"102349","DOI":"10.1016\/j.mtbio.2025.102349","article-title":"Smart biomaterials in restorative dentistry: Recent advances and future perspectives","volume":"35","author":"Sun","year":"2025","journal-title":"Mater. Today Bio"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/j.dental.2024.06.011","article-title":"The influence of hygroscopic expansion of resin supporting dies on the fracture resistance of ceramic restorations during thermal cycling","volume":"40","author":"Li","year":"2024","journal-title":"Dent. Mater."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"104218","DOI":"10.1016\/j.jdent.2022.104218","article-title":"Effects of thermal cycling on mechanical and antibacterial durability of bioactive low-shrinkage-stress nanocomposite","volume":"124","author":"Filemban","year":"2022","journal-title":"J. Dent."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1177\/0022034513490734","article-title":"Factors involved in mechanical fatigue degradation of dental resin composites","volume":"92","author":"Lohbauer","year":"2013","journal-title":"J. Dent. Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jmbbm.2018.08.008","article-title":"Recent advances in understanding the fatigue and wear behavior of dental composites and ceramics","volume":"88","author":"Kruzic","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_31","first-page":"25","article-title":"Analysis of survival probability and reliability of tooth-composite filling system","volume":"2","author":"Pieniak","year":"2011","journal-title":"Eksploat. I Niezawodn.\u2013Maint. Reliab."},{"key":"ref_32","first-page":"181","article-title":"Influence of thermal fatigue and ageing on microhardness of polymer-ceramic composites for biomedical applications","volume":"14","author":"Pieniak","year":"2012","journal-title":"Eksploat. Niezawodn."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Szczesio-Wlodarczyk, A., Barszczewska-Rybarek, I.M., Chr\u00f3szcz-Por\u0119bska, M.W., Kopacz, K., Sokolowski, J., and Bociong, K. (2023). Can modification with urethane derivatives or the addition of an anti-hydrolysis agent influence the hydrolytic stability of resin dental composite?. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24054336"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.dental.2003.05.007","article-title":"Residual shrinkage stress distributions in molars after composite restoration","volume":"20","author":"Versluis","year":"2004","journal-title":"Dent. Mater."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.dental.2017.04.013","article-title":"Academy of Dental Materials guidance\u2014Resin composites: Part I\u2014Mechanical properties","volume":"33","author":"Ilie","year":"2017","journal-title":"Dent. Mater."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1016\/j.biomaterials.2003.09.078","article-title":"Thermal expansion characteristics of light-cured dental resins and resin composites","volume":"25","author":"Sideridou","year":"2004","journal-title":"Biomaterials"},{"key":"ref_37","unstructured":"Nowacki, W. (1986). Thermoelasticity, Pergamon Press. [2nd ed.]."},{"key":"ref_38","first-page":"2203","article-title":"Experimental and analytical study of surface fatigue life in dental composites","volume":"4","author":"Marandu","year":"2015","journal-title":"J. Compos. Mater."},{"key":"ref_39","unstructured":"Niewczas, A.M. (2011, January 26\u201329). Application of censored survival data for evaluation of the dental restorations replacement criteria. Proceedings of the International Conference on Risk Analysis (ICRA 4), Limassol, Cyprus."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1046\/j.1365-2842.1999.00346.x","article-title":"In vitro study on the effect of thermo- and load-cycling on the bond strength of porcelain repair systems","volume":"26","author":"Leibrock","year":"1999","journal-title":"J. Oral Rehabil."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1023\/A:1016504530133","article-title":"Effect of thermal cycling of whiskers-reinforced dental resin composites","volume":"13","author":"Xu","year":"2002","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_42","first-page":"226","article-title":"Reattachment of fractured teeth: A review of literature regarding techniques and materials","volume":"29","author":"Reis","year":"2004","journal-title":"Oper. Dent."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/jbm.a.32016","article-title":"Work of fracture of a composite resin: Fracture-toughening mechanisms","volume":"89","author":"Baudin","year":"2009","journal-title":"J. Biomed. Mater. Res. A"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1600-9657.2010.00906.x","article-title":"Reattachment of anterior fractured teeth: Effect of materials and techniques on impact strength","volume":"26","author":"Alonso","year":"2010","journal-title":"Dent. Traumatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1002\/pc.25232","article-title":"Effect of micro-\/nano-hybrid hydroxyapatite rod reinforcement in composite resins on strength through thermal cycling","volume":"40","author":"Wu","year":"2019","journal-title":"Polym. Compos."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"109495","DOI":"10.1016\/j.compositesb.2021.109495","article-title":"Dental resin composites: A review on materials to product realizations","volume":"230","author":"Cho","year":"2022","journal-title":"Compos. Part B Eng."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Zubrzycki, J., Klepka, T., Marchewka, M., and Zubrzycki, R. (2022). Tests of dental properties of composite materials containing nanohybrid filler. Materials, 16.","DOI":"10.3390\/ma16010348"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"761","DOI":"10.13005\/bpj\/3126","article-title":"Strength of bond between adhesives and low-viscosity bulk-fill composites utilizing 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP)","volume":"18","author":"Katta","year":"2025","journal-title":"Biomed. Pharmacol. J."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Duki\u0107, W., Maji\u0107, M., Prica, N., and Ore\u0161ki, I. (2021). Clinical evaluation of flowable composite materials in permanent molars small class I restorations: 3-year double blind clinical study. Materials, 14.","DOI":"10.3390\/ma14154283"},{"key":"ref_50","unstructured":"(2026, May 26). 3M\u2122 Filtek\u2122 Z550\u2014A Universal Nanohybrid Composite Material for Fillings. It Offers High Strength, Aesthetic Appearance and Is Easy to Polish. 3M Poland. Available online: https:\/\/www.solventum.com\/pl-pl\/home\/f\/b00007982\/#product-specifications."},{"key":"ref_51","unstructured":"(2026, May 26). 3M\u2122 Filtek\u2122 Ultimate Flow\u2014A Universal, Low-Viscosity, Light-Cured Composite Material for a Variety of Applications in Dentistry. 3M Poland. Available online: https:\/\/www.solventum.com\/pl-pl\/home\/f\/b00007942\/#product-specifications."},{"key":"ref_52","unstructured":"(2019). Dentistry\u2014Polymer-Based Restorative Materials (Standard No. ISO 4049:2019)."},{"key":"ref_53","unstructured":"(2024). Dentistry\u2014Ceramic Materials (Standard No. ISO 6872:2024)."},{"key":"ref_54","unstructured":"(2020). Standard Test Method for Linear-Elastic Plane-Strain Fracture Toughness of Metallic Materials (Standard No. ASTM E399-20)."},{"key":"ref_55","unstructured":"(2018). Testing of Plastics\u2014Bending Test and Impact Test on Dynstat Test Specimens (Standard No. DIN 53435:2018)."},{"key":"ref_56","unstructured":"(2020). Dentistry\u2014Corrosion Test Methods for Metallic Materials (Standard No. ISO 10271:2020)."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Szczesio-Wlodarczyk, A., Sokolowski, J., Kleczewska, J., and Bociong, K. (2020). Ageing of dental composites based on methacrylate resins\u2014A critical review of the causes and method of assessment. Polymers, 12.","DOI":"10.3390\/polym12040882"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"104401","DOI":"10.1016\/j.jmbbm.2021.104401","article-title":"Effect of thermocycling on the surface properties of resin-matrix CAD-CAM ceramics after different surface treatments","volume":"117","author":"Yilmaz","year":"2021","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_59","unstructured":"Niewczas, J., Zamo\u015bci\u0144ska, J., Krzy\u017cak, A., Pieniak, D., Walczak, A., and Bartnik, G. (2017). Influence of fibre reinforcement on selected mechanical properties of dental composites. Acta Bioeng. Biomech."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1515\/adms-2017-0034","article-title":"Initiation and tolerance of macro-damage of first ply (FBF) in a process of damaging of hybrid multi-ply structures due to reinforcement architecture","volume":"18","author":"Pieniak","year":"2018","journal-title":"Adv. Mater. Sci."},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Thomaidis, S., Pappa, E., and Antoniadou, M. (2025). Fracture toughness of CAD\/CAM resin-based materials vs. direct composite resins: A Scoping review. Appl. Sci., 15.","DOI":"10.3390\/app152212308"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Perez, N. (2017). Fracture Mechanics, Springer International Publishing.","DOI":"10.1007\/978-3-319-24999-5"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.dental.2025.09.007","article-title":"In situ investigation of the fracture toughening mechanisms of bioinspired dental ceramic composites with different compliant polymer phases","volume":"41","author":"Jargalsaikhan","year":"2025","journal-title":"Dent. Mater."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"57","DOI":"10.5005\/jp-journals-10005-1711","article-title":"A comparative evaluation of fracture toughness of composite resin vs Protemp 4 for use in strip crowns: An in vitro study","volume":"13","author":"Vignesh","year":"2020","journal-title":"Int. J. Clin. Pediatr. Dent."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e132","DOI":"10.1016\/j.dental.2013.04.025","article-title":"Mechanical properties of contemporary composite resins and their interrelations","volume":"29","author":"Thomaidis","year":"2013","journal-title":"Dent. Mater."},{"key":"ref_66","first-page":"201990","article-title":"Weibull reliability methodology based on cumulated vibration damage","volume":"27","year":"2025","journal-title":"Eksploat. Niezawodn."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/pi.70085","article-title":"Dental composites: A comprehensive review on formulation, properties and recent developments","volume":"75","author":"Latoui","year":"2025","journal-title":"Polym. Int."},{"key":"ref_68","first-page":"199426","article-title":"Reliability assessment of competitive failure systems based on three parameter Weibull distribution and Wiener process","volume":"27","author":"Shangguan","year":"2024","journal-title":"Eksploat. Niezawodn."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"238","DOI":"10.4236\/jbnb.2012.32029","article-title":"Evaluation the mechanical properties of nanofilled composite resin restorative material","volume":"3","author":"Hamouda","year":"2012","journal-title":"J. Biomater. Nanobiotechnol."},{"key":"ref_70","first-page":"558","article-title":"Fracture resistance curves and toughening mechanisms in polymer based dental composites","volume":"4","author":"Goutianos","year":"2001","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.prosdent.2023.07.041","article-title":"Performance of direct and indirect onlay restorations for structurally compromised teeth","volume":"133","author":"Althaqafi","year":"2025","journal-title":"J. Prosthet. Dent."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"100655","DOI":"10.1016\/j.rinma.2024.100655","article-title":"An extensive review on bibliometric analysis of carbon nanostructure reinforced composites","volume":"25","author":"Siddiqui","year":"2025","journal-title":"Results Mater."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"232","DOI":"10.12913\/22998624\/147515","article-title":"Effect of water absorption on tribological properties of thermoplastics matrix composites reinforced with glass fibres","volume":"16","author":"Walczak","year":"2022","journal-title":"Adv. Sci. Technol. Res. J."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.dental.2005.05.005","article-title":"Hygroscopic and hydrolytic effects in dental polymer networks","volume":"22","author":"Ferracane","year":"2006","journal-title":"Dent. Mater."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"101140","DOI":"10.1016\/j.mser.2025.101140","article-title":"Advances in stimuli-responsive polymers for biomedical and environmental applications","volume":"168","author":"Kang","year":"2026","journal-title":"Mater. Sci. Eng. R Rep."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Afzal, A., and Shaker, K. (2026). Hydrothermal degradation of polymer nanocomposites. Aging and Degradation of Polymer Nanocomposites, Woodhead Publishing.","DOI":"10.1016\/B978-0-443-28864-7.00008-6"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.dental.2026.02.012","article-title":"Filler amount influences long-term mechanical stability of experimental dental composites","volume":"42","author":"Troha","year":"2026","journal-title":"Dent. Mater."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"176089","DOI":"10.1016\/j.cej.2026.176089","article-title":"Piezoelectric-pyroelectric inorganic filler synergistically endows dental resin composite with long-term self-bactericidal potential","volume":"536","author":"Huang","year":"2026","journal-title":"Chem. Eng. J."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1016\/j.prosdent.2025.11.040","article-title":"Properties of 3D printed resins for definitive dental restorations: A systematic review","volume":"135","author":"Flottes","year":"2026","journal-title":"J. Prosthet. Dent."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"100015","DOI":"10.1016\/j.scsadv.2025.100015","article-title":"Experimental studies on environmental constraints and remedial measures for environmental sustainability: A review","volume":"2","author":"Vennapusa","year":"2026","journal-title":"Sustain. Cities Soc. Adv."},{"key":"ref_81","first-page":"e05625","article-title":"A comprehensive review of materials, processing, and performance of nano-doped engineered geopolymer composites for construction applications","volume":"23","author":"Vignesh","year":"2025","journal-title":"Case Stud. Constr. Mater."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"100925","DOI":"10.1016\/j.nexres.2025.100925","article-title":"Exploring the sources and routes of micro- and nanoplastics from dental products and materials: Their impact on human health\u2014A systematic review","volume":"2","author":"Selvaraj","year":"2025","journal-title":"Next Res."},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Ahmed, I.U. (2026). Role of nanotechnology in remediation of microplastics from aquatic environments. Remediation Technologies for Microplastics in Aquatic Environments, Elsevier.","DOI":"10.1016\/B978-0-443-33829-8.00009-9"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.dental.2022.06.029","article-title":"Fracture toughness of conventional, milled and 3D printed denture bases","volume":"38","author":"Mann","year":"2022","journal-title":"Dent. Mater."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"46300","DOI":"10.1016\/j.ceramint.2024.08.473","article-title":"Enhancing the mechanical performance of 3D-printed self-hardening calcium phosphate bone scaffolds: PLGA-based strategies","volume":"50","author":"Johansson","year":"2024","journal-title":"Ceram. Int."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"214245","DOI":"10.1016\/j.bioadv.2025.214245","article-title":"Enhancing calcium phosphate cements: A review of bacterial cellulose (BC) and other biopolymer reinforcements for biomedical applications","volume":"172","author":"Muhamad","year":"2025","journal-title":"Biomater. Adv."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.dental.2026.03.001","article-title":"Predictive modeling of composite fracture toughness using machine learning","volume":"42","author":"Tonin","year":"2026","journal-title":"Dent. Mater."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.dental.2023.03.002","article-title":"Effect of silane coupling agent and concentration on fracture toughness and water sorption behaviour of fibre-reinforced dental composites","volume":"39","author":"Cho","year":"2023","journal-title":"Dent. Mater."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"145603","DOI":"10.1016\/j.conbuildmat.2026.145603","article-title":"Fracture toughness and fracture energy of polymeric concrete with variable mixtures designed by the L32 Taguchi method and statistical analysis of pore sizes in the fracture surface","volume":"515","author":"Aliha","year":"2026","journal-title":"Constr. Build. Mater."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"14389","DOI":"10.1016\/j.ceramint.2017.07.202","article-title":"The morphological effect of calcium phosphates as reinforcement in methacrylate-based dental composite resins on mechanical strength through thermal cycling","volume":"43","author":"Wu","year":"2017","journal-title":"Ceram. Int."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1016\/j.identj.2024.11.020","article-title":"Advances of hydroxyapatite nanoparticles in dental implant applications","volume":"75","author":"Islam","year":"2025","journal-title":"Int. Dent. J."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"115000","DOI":"10.1016\/j.mtcomm.2026.115000","article-title":"Functionally graded materials: Development, processing techniques, and emerging applications\u2014A comprehensive review","volume":"52","author":"Sahoo","year":"2026","journal-title":"Mater. Today Commun."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.wear.2006.12.010","article-title":"The relationship between physical parameters and wear of dental composites","volume":"263","author":"Heintze","year":"2007","journal-title":"Wear"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"108322","DOI":"10.1016\/j.triboint.2023.108322","article-title":"Investigation of physical, mechanical, thermal, and tribological characterization of tricalcium phosphate and zirconia particulate reinforced dental resin composite materials","volume":"181","author":"Saini","year":"2023","journal-title":"Tribol. Int."},{"key":"ref_95","first-page":"100002","article-title":"Occlusal wear in dental prostheses milled from a two-colored shell-geometry disk: A prospective clinical pilot study","volume":"1","author":"Casucci","year":"2025","journal-title":"Digit. Dent. J."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"106619","DOI":"10.1016\/j.jdent.2026.106619","article-title":"Wear, fracture strength, and reliability of three-unit definitive fixed dental prostheses fabricated with different vat polymerization methods","volume":"169","author":"Deniz","year":"2026","journal-title":"J. Dent."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/(SICI)1097-4636(19981205)42:3<465::AID-JBM17>3.0.CO;2-F","article-title":"In vitro aging of dental composites in water\u2014Effect of degree of conversion, filler volume, and filler\/matrix coupling","volume":"42","author":"Ferracane","year":"1998","journal-title":"J. Biomed. Mater. Res."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.dental.2013.08.201","article-title":"Biodegradation of resin composites and adhesives by oral bacteria and saliva: A rationale for new material designs that consider the clinical environment and treatment challenges","volume":"30","author":"Delaviz","year":"2014","journal-title":"Dent. Mater."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jdsr.2025.05.002","article-title":"Utilization of cellulose nanofiber in dental applications: A systematic review of in vitro evidence","volume":"61","author":"Yang","year":"2025","journal-title":"Jpn. Dent. Sci. Rev."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.actbio.2025.10.061","article-title":"Pathways of neutrophil enzymatic degradation of resin-based composites and adhesives","volume":"208","author":"Peled","year":"2025","journal-title":"Acta Biomater."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1016\/j.dental.2024.07.006","article-title":"Synthesis and challenges of fluorinated divinyl urethane monomers as a strategy for masking hydrolytic sensitive methacrylate groups in resin composites","volume":"40","author":"Lagowski","year":"2024","journal-title":"Dent. Mater."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"106572","DOI":"10.1016\/j.jdent.2026.106572","article-title":"Immune and microbial cellular interactions with contemporary and alternative resin-based dental restorative materials","volume":"167","author":"Gouveia","year":"2026","journal-title":"J. Dent."}],"container-title":["Journal of Functional Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-4983\/17\/6\/276\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T04:32:32Z","timestamp":1780720352000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-4983\/17\/6\/276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":102,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["jfb17060276"],"URL":"https:\/\/doi.org\/10.3390\/jfb17060276","relation":{},"ISSN":["2079-4983"],"issn-type":[{"value":"2079-4983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]}}}