{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T12:50:38Z","timestamp":1763988638748,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Comprehensive Rehabilitation Program","award":["40000882-0"],"award-info":[{"award-number":["40000882-0"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFMK"],"abstract":"<jats:p>Background: Functional disability is a growing concern in aging populations with chronic health conditions, yet few studies have compared disability profiles across diagnostic categories using standardized tools. Objectives: This study aimed to characterize the functional profiles of adults with neurological, musculoskeletal, and chronic pain conditions using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) and to examine differences by age and sex. Methods: A total of 419 participants (median age = 73 years; 73% female) completed the 36-item WHODAS 2.0. Diagnoses were classified into three groups: neurological (n = 134), musculoskeletal (n = 230), and pain-related (n = 55). Domain-level scores were analyzed using non-parametric tests and Spearman correlations. Results: revealed that neurological conditions were associated with the highest disability levels, particularly in cognition, interpersonal relations, and participation. Musculoskeletal conditions showed greater impairments in mobility and self-care, while pain-related conditions demonstrated variable disability, especially in participation. Women reported higher disability scores in the neurologic group, with significant differences observed in the cognition domain among neurological cases (p = 0.048). Age was positively correlated with disability in self-care and mobility, especially in musculoskeletal conditions. Conclusions: These findings highlight the utility of WHODAS 2.0 in identifying domain-specific limitations across clinical populations. They support the need for individualized, diagnosis- and gender-sensitive rehabilitation strategies, and suggest that WHODAS 2.0 can inform targeted care planning and resource allocation in rehabilitation settings. Future research should incorporate longitudinal designs and explore contextual factors influencing functional outcomes.<\/jats:p>","DOI":"10.3390\/jfmk10030312","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T15:16:37Z","timestamp":1755184597000},"page":"312","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Functional Profile Differences Across Diagnostic Categories Using WHODAS 2.0 in Adults with Neurological, Musculoskeletal, and Chronic Pain Conditions"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4088-9820","authenticated-orcid":false,"given":"Patricio","family":"Barria","sequence":"first","affiliation":[{"name":"Research and Development Area, Corporaci\u00f3n de Rehabilitaci\u00f3n Club de Leones Cruz del Sur, Punta Arenas 6210005, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asterio","family":"Andrade","sequence":"additional","affiliation":[{"name":"Research and Development Area, Corporaci\u00f3n de Rehabilitaci\u00f3n Club de Leones Cruz del Sur, Punta Arenas 6210005, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5129-7880","authenticated-orcid":false,"given":"Bessi\u00e9 C\u00f3rdova","family":"Albayay","sequence":"additional","affiliation":[{"name":"Research and Development Area, Corporaci\u00f3n de Rehabilitaci\u00f3n Club de Leones Cruz del Sur, Punta Arenas 6210005, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5228-5763","authenticated-orcid":false,"given":"Felipe","family":"Covarrubias-Escudero","sequence":"additional","affiliation":[{"name":"Translational Research Unit, Trainfes Center, Santiago 8760903, Chile"},{"name":"Department of Kinesiology, Faculty of Art and Physical Education, Universidad Metropolitana de Ciencias de la Educaci\u00f3n, Santiago 7750332, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6942-865X","authenticated-orcid":false,"given":"Carlos","family":"Cifuentes","sequence":"additional","affiliation":[{"name":"Bristol Robotics Laboratory, University of the West of England, Bristol BS16 1QY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9561-7764","authenticated-orcid":false,"given":"Juan Camilo","family":"Moreno","sequence":"additional","affiliation":[{"name":"Center for Automation and Robotics, UPM-CSIC, 28500 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1866-5022","authenticated-orcid":false,"given":"Juan Pablo","family":"Appelgren-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Translational Research Unit, Trainfes Center, Santiago 8760903, Chile"},{"name":"Center of Biomedical Imaging, Pontificia Universidad Cat\u00f3lica de Chile, Santiago 7510000, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2021). 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