{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T21:24:03Z","timestamp":1782768243250,"version":"3.54.5"},"reference-count":50,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFMK"],"abstract":"<jats:p>Transcutaneous electrical nerve stimulation (TENS) has proven effective in treating pain in many experimental and clinical studies. In addition to the analgesic effect, direct TENS of peripheral nerves had anti-inflammatory and regenerative effects in the treatment of distal polyneuropathy and spinal cord injury. This work demonstrates the experience of using direct TENS in the treatment of a 52-year-old patient with post-COVID-19 Guillain\u2013Barr\u00e9 (GBS) and acute transverse myelitis (ATM) overlap syndrome. Direct TENS of peripheral nerves showed high efficiency in enhancing the therapeutic effect of combined plasma exchange and pharmacotherapy by 89.5% with a significant reduction in neuropathic pain, motor and sensory deficits, bladder and bowel disorders and regression of neurophysiological changes. We suggest that direct TENS of peripheral nerves can be a promising option for combined therapy of GBS and ATM overlap syndrome and other diseases with the simultaneous development of distal polyneuropathy and spinal cord injury. Further trial studies are required.<\/jats:p>","DOI":"10.3390\/jfmk9010040","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T07:51:39Z","timestamp":1708933899000},"page":"40","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Functional Recovery and Regenerative Effects of Direct Transcutaneous Electrical Nerve Stimulation in Treatment of Post-COVID-19 Guillain\u2013Barr\u00e9 and Acute Transverse Myelitis Overlap Syndrome: A Clinical Case"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3643-982X","authenticated-orcid":false,"given":"Mustafa","family":"Al-Zamil","sequence":"first","affiliation":[{"name":"Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples\u2019 Friendship University of Russia, 117198 Moscow, Russia"},{"name":"Department of Restorative Medicine and Neurorehabilitation, Medical Dental Institute, 127253 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia G.","family":"Kulikova","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples\u2019 Friendship University of Russia, 117198 Moscow, Russia"},{"name":"Department of Sports Medicine and Medical Rehabilitation, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inessa A.","family":"Minenko","sequence":"additional","affiliation":[{"name":"Department of Restorative Medicine and Neurorehabilitation, Medical Dental Institute, 127253 Moscow, Russia"},{"name":"Department of Sports Medicine and Medical Rehabilitation, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Numman","family":"Mansur","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples\u2019 Friendship University of Russia, 117198 Moscow, Russia"},{"name":"Department of Restorative Medicine and Neurorehabilitation, Medical Dental Institute, 127253 Moscow, Russia"},{"name":"City Clinical Hospital Named after V. V. Vinogradov, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis M.","family":"Zalozhnev","sequence":"additional","affiliation":[{"name":"Department of Restorative Medicine and Neurorehabilitation, Medical Dental Institute, 127253 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marat B.","family":"Uzdenov","sequence":"additional","affiliation":[{"name":"Medical Institute, North Caucasian State Academy, 369001 Cherkessk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7911-7892","authenticated-orcid":false,"given":"Alina A.","family":"Dzhanibekova","sequence":"additional","affiliation":[{"name":"Medical Institute, North Caucasian State Academy, 369001 Cherkessk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alikhan A.","family":"Gochiyayev","sequence":"additional","affiliation":[{"name":"Medical Institute, North Caucasian State Academy, 369001 Cherkessk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2840-837X","authenticated-orcid":false,"given":"Natalia A.","family":"Shnayder","sequence":"additional","affiliation":[{"name":"Institute of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, 192019 Saint Petersburg, Russia"},{"name":"Shared Core Facilities \u201cMolecular and Cell Technologies\u201d, Professor V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5535\/arm.2015.39.1.142","article-title":"Concomitant acute transverse myelitis and sensory motor axonal polyneuropathy in two children: Two case reports","volume":"39","author":"Chung","year":"2015","journal-title":"Ann. Rehabil. 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