{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T11:27:20Z","timestamp":1787052440940,"version":"build-2736575974"},"reference-count":43,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Aarau Kantonsspital Research Fund","award":["1410.000.210"],"award-info":[{"award-number":["1410.000.210"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Imaging"],"abstract":"<jats:p>A transient ischemic attack (TIA) is a transient episode of neurological dysfunction without evidence of acute infarct demarcation on neuroimaging. The radiographic features of TIAs are uncertain, as since there is currently no perfect imaging method with which to differentiate a stroke from a TIA. We aimed to evaluate whether regional abnormalities are associated with TIA by identifying tissue with increased susceptibility (\u03c7) values using quantitative susceptibility mapping (QSM). A total of 39 adults with clinical TIA symptoms (66 \u00b1 12 years) and 39 age- and sex matched controls (65 \u00b1 12 years) underwent MRI. Based on the QSM-maps, local susceptibility changes were tested for statistically significant differences between patients with TIA and healthy controls. The susceptibility maps of TIA patients showed that magnetic susceptibility differed from that of healthy volunteers, with the strongest effects observable in the right lingual gyrus (p &lt; 0.001) and bilaterally in the caudal anterior cingulate (cACC, p &lt; 0.01). TIA is often difficult to diagnose at the time of presentation in the emergency department, and QSM could show an association between regional QSM abnormalities and TIA.<\/jats:p>","DOI":"10.3390\/jimaging12080387","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:35:08Z","timestamp":1786984508000},"page":"387","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative MRI Susceptibility: Mapping of Transient Ischemic Attack\u2014A Preliminary Study"],"prefix":"10.3390","volume":"12","author":[{"given":"Philipp","family":"Gruber","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Diepers","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5623-1313","authenticated-orcid":false,"given":"Markus","family":"Gschwind","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kantonsspital Aarau, 5001 Aarau, Switzerland"},{"name":"Department of Clinical Neurosciences, University Hospitals of Geneva (HUG), 1211 Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul G.","family":"Unschuld","sequence":"additional","affiliation":[{"name":"Division of Geriatric Psychiatry, University Hospitals of Geneva (HUG), 1211 Geneva, Switzerland"},{"name":"Department of Psychiatry, University of Geneva (UniGE), 1211 Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5894-6853","authenticated-orcid":false,"given":"Luca","family":"Remonda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7502-4814","authenticated-orcid":false,"given":"Franca","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"},{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Mordasini","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6551-8308","authenticated-orcid":false,"given":"Jatta","family":"Berberat","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Kantonsspital Aarau, 5001 Aarau, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1161\/STROKEAHA.108.192218","article-title":"Definition and evaluation of transient ischemic attack: A scientific statement for healthcare professionals from the American Heart Association\/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. 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