{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:37:05Z","timestamp":1789684625501,"version":"4.0.1"},"reference-count":10,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Acute Leukemia Advocates Network (ALAN)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMAHP"],"abstract":"<jats:p>Patient involvement in health technology assessment (HTA) processes is increasingly recognized as pivotal for informed, equitable, and patient-relevant health care decision-making. With the implementation of Joint Scientific Consultations (JSCs) and Joint Clinical Assessments (JCAs) under Regulation (EU) 2021\/2282, the European Union has a unique opportunity to design harmonized mechanisms that reflect best practices from established HTA systems. This article, drawing on the Acute Leukemia Advocates Network (ALAN)\u2019s comparative analysis of HTA practices across seven countries (Canada, England, Scotland, France, Germany, Spain, and Italy), examines how current patient involvement processes can inform the JCA framework. It identifies opportunities to replicate effective practices and proposes strategies to embed patient voices meaningfully into the JCA process. By prioritizing robust and inclusive patient involvement, the EU can establish a global benchmark for impactful and consistent HTA processes. By leveraging lessons from international HTA systems and prioritizing clear frameworks, early involvement, and capacity building, the EU can set a global standard for meaningful patient participation in HTA processes. ALAN is an independent global network of patient organizations dedicated to improving outcomes for patients with acute leukemia.<\/jats:p>","DOI":"10.3390\/jmahp13030038","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T08:51:33Z","timestamp":1753692693000},"page":"38","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Patient Involvement in Health Technology Assessments: Lessons for EU Joint Clinical Assessments"],"prefix":"10.3390","volume":"13","author":[{"given":"Anne-Pierre","family":"Pickaert","sequence":"first","affiliation":[{"name":"Acute Leukemia Advocates Network (ALAN), CH-3000 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1017\/S0266462320000215","article-title":"The new definition of health technology assessment: A milestone in international collaboration","volume":"36","author":"Oortwijn","year":"2020","journal-title":"Int. J. Technol. Assess. Health Care"},{"key":"ref_2","unstructured":"European Commission (EC) (2025, January 08). Health Technology Assessment, Overview. Available online: https:\/\/health.ec.europa.eu\/health-technology-assessment\/overview_en."},{"key":"ref_3","unstructured":"European Commission (EC) (2025, January 08). Questions and Answers: Adoption of Regulation on Health Technology Assessment. Available online: https:\/\/ec.europa.eu\/commission\/presscorner\/detail\/en\/qanda_21_6773."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40900-020-00248-9","article-title":"Patients and public are important stakeholders in health technology assessment, but the level of involvement is low\u2014A call to action","volume":"7","author":"Wale","year":"2021","journal-title":"Res. Involv. Engagem."},{"key":"ref_5","unstructured":"Acute Leukemia Advocates Network (ALAN) (2025, January 08). Patient Involvement in Health Technology Assessment of Medicines for the Purpose of Reimbursement: An Exploratory Comparative Report. Available online: https:\/\/acuteleuk.org\/publications\/."},{"key":"ref_6","unstructured":"Office of Health Economics (OHE) (2025, January 08). Incorporating the Patient Voice in Health Technology Assessment. Available online: https:\/\/www.ohe.org\/publications\/patient-voice-in-hta."},{"key":"ref_7","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 (HAS) (2025, January 08). CT Commission de la Transparence. Rapport d\u2019Activit\u00e9. Available online: https:\/\/www.has-sante.fr\/upload\/docs\/application\/pdf\/2023-06\/rapport_dactivite_2022_de_la_ct.pdf."},{"key":"ref_8","unstructured":"European Patient Forum (EPF) (2025, January 08). EPF Feedback on the Implementing Act on Joint Clinical Assessments of Medicinal Products. Available online: https:\/\/www.eu-patient.eu\/news\/latest-epf-news\/2024\/epf-feedback-on-the-implementing-act-on-joint-clinical-assessments-of-medicinal-products\/."},{"key":"ref_9","unstructured":"Cancer Patients Europe (CPE), European Federation of Allergy and Airways Diseases Patients\u2019 Association (EFA), European Haemophilia Consortium (EHC), European Kidney Patients\u2019 Federation (EKPF), European Multiple Sclerosis Platform (EMSP), European Patients Forum (EPF), European Pulmonary Fibrosis Federation (EU-PFF), France Assos Sant\u00e9 (FAS), Lymphoma Coalition, and Myeloma Patients Europe (MPE) (2025, January 08). 10 Key Recommendations from Patient Organisations on Joint Clinical Assessments Under the EU HTA Regulation. Available online: https:\/\/www.eu-patient.eu\/news\/latest-epf-news\/2024\/10-key-recommendations-for-enhancing-joint-clinical-assessments-under-the-eu-hta-regulation\/."},{"key":"ref_10","unstructured":"European Patient Forum (EPF) (2025, January 08). EPF\u2019s Feedback to the Implementing Act on HTA Cooperation with the EMA. Available online: https:\/\/www.eu-patient.eu\/news\/latest-epf-news\/2024\/epfs-feedback-to-the-implementing-act-on-hta-cooperation-with-the-ema2\/."}],"container-title":["Journal of Market Access &amp; Health Policy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2001-6689\/13\/3\/38\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:17:07Z","timestamp":1760033827000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2001-6689\/13\/3\/38"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9]]}},"alternative-id":["jmahp13030038"],"URL":"https:\/\/doi.org\/10.3390\/jmahp13030038","relation":{},"ISSN":["2001-6689"],"issn-type":[{"value":"2001-6689","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]}}}