{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:17:37Z","timestamp":1781176657161,"version":"3.54.1"},"reference-count":40,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:00:00Z","timestamp":1708560000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Chromoblastomycosis (CBM) is a chronic neglected fungal disease, usually met in tropical areas. French Guiana is a South American territory with limited epidemiological data. This retrospective study concerned all patients with CBM proven by at least one paraclinical examination and diagnosed in French Guiana between 1950 and 2023. In total, 23 patients were included, mostly males (87%) of Creole origin, living in the coastal region (87%) and involved in outdoor occupations (74%). Lesions were mostly observed on the lower limbs (78.3%), with a median time to diagnosis of four years. Laboratory tests included positive direct microscopic examinations (78.3%) and mycological cultures (69.6%), identifying 14 cases of Fonsecaea pedrosoi and one case of Exophiala janselmei. Various treatments were employed, including antifungals, surgery and combinations of both. In conclusion, CBM in French Guiana involves a different population than other subcutaneous mycoses such as Lobomycosis or Paracoccidioidomycosis, mostly found in the forest hinterland. Surgery should be recommended for recent and limited lesions. Itraconazole and terbinafine should systematically be proposed, either in monotherapy or in combination with surgery or cryotherapy.<\/jats:p>","DOI":"10.3390\/jof10030168","type":"journal-article","created":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T08:34:35Z","timestamp":1708590875000},"page":"168","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Chromoblastomycosis in French Guiana: Epidemiology and Practices, 1955\u20132023"],"prefix":"10.3390","volume":"10","author":[{"given":"Julie","family":"Valentin","sequence":"first","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Grotta","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"},{"name":"Department of Pathology, Center of Biological Resources (CRB Amazonie), Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Muller","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Bourgeois","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinan","family":"Drak Alsibai","sequence":"additional","affiliation":[{"name":"Department of Pathology, Center of Biological Resources (CRB Amazonie), Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3414-0821","authenticated-orcid":false,"given":"Magalie","family":"Demar","sequence":"additional","affiliation":[{"name":"Laboratory of Parasitology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"},{"name":"Tropical Biome and Immunophysiopathology (TBIP), Universit\u00e9 de Lille, CNRS, Inserm, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d\u2019Infection et d\u2019Immunit\u00e9 de Lille, Centre Hospitalier de Cayenne, Universit\u00e9 de Guyane, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Couppie","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"},{"name":"Tropical Biome and Immunophysiopathology (TBIP), Universit\u00e9 de Lille, CNRS, Inserm, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d\u2019Infection et d\u2019Immunit\u00e9 de Lille, Centre Hospitalier de Cayenne, Universit\u00e9 de Guyane, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Blaizot","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Andr\u00e9e Rosemon Hospital, 97306 Cayenne, French Guiana"},{"name":"Tropical Biome and Immunophysiopathology (TBIP), Universit\u00e9 de Lille, CNRS, Inserm, Institut Pasteur de Lille, U1019-UMR9017-CIIL-Centre d\u2019Infection et d\u2019Immunit\u00e9 de Lille, Centre Hospitalier de Cayenne, Universit\u00e9 de Guyane, 97306 Cayenne, French Guiana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e367","DOI":"10.1016\/S1473-3099(17)30306-7","article-title":"Neglected endemic mycoses","volume":"17","author":"Fahal","year":"2017","journal-title":"Lancet Infect. 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