{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:42:45Z","timestamp":1791873765737,"version":"4.3.4"},"reference-count":170,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institutes of Health","award":["R01NS10875"],"award-info":[{"award-number":["R01NS10875"]}]},{"name":"National Institutes of Health","award":["R01AI134636"],"award-info":[{"award-number":["R01AI134636"]}]},{"name":"National Institutes of Health","award":["R01AI176922"],"award-info":[{"award-number":["R01AI176922"]}]},{"name":"National Institutes of Health","award":["F30AI155292"],"award-info":[{"award-number":["F30AI155292"]}]},{"name":"National Institutes of Health","award":["T32GM008244"],"award-info":[{"award-number":["T32GM008244"]}]},{"name":"University of Minnesota Medical Scientist Training Program (MSTP) under NIH","award":["R01NS10875"],"award-info":[{"award-number":["R01NS10875"]}]},{"name":"University of Minnesota Medical Scientist Training Program (MSTP) under NIH","award":["R01AI134636"],"award-info":[{"award-number":["R01AI134636"]}]},{"name":"University of Minnesota Medical Scientist Training Program (MSTP) under NIH","award":["R01AI176922"],"award-info":[{"award-number":["R01AI176922"]}]},{"name":"University of Minnesota Medical Scientist Training Program (MSTP) under NIH","award":["F30AI155292"],"award-info":[{"award-number":["F30AI155292"]}]},{"name":"University of Minnesota Medical Scientist Training Program (MSTP) under NIH","award":["T32GM008244"],"award-info":[{"award-number":["T32GM008244"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Animal models are frequently used as surrogates to understand human disease. In the fungal pathogen Cryptococcus species complex, several variations of a mouse model of disease were developed that recapitulate different aspects of human disease. These mouse models have been implemented using various inbred and outbred mouse backgrounds, many of which have genetic differences that can influence host response and disease outcome. In this review, we will discuss the most commonly used inbred mouse backgrounds in C. neoformans infection models.<\/jats:p>","DOI":"10.3390\/jof10060426","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T08:48:31Z","timestamp":1718614111000},"page":"426","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Inbred Mouse Models in Cryptococcus neoformans Research"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7497-8157","authenticated-orcid":false,"given":"Minna","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2318-168X","authenticated-orcid":false,"given":"Kirsten","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nature10413","article-title":"Mouse genomic variation and its effect on phenotypes and gene regulation","volume":"477","author":"Keane","year":"2011","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1128\/IAI.67.8.3703-3713.1999","article-title":"Host-pathogen interactions: Redefining the basic concepts of virulence and pathogenicity","volume":"67","author":"Casadevall","year":"1999","journal-title":"Infect. 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