{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:07:22Z","timestamp":1785434842717,"version":"3.56.0"},"reference-count":73,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Sigma Xi","award":["G01456"],"award-info":[{"award-number":["G01456"]}]},{"award":["G01456"],"award-info":[{"award-number":["G01456"]}],"id":[{"id":"https:\/\/ror.org\/04nmj5x57","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Members of Fusarium oxysporum species complex (FOSC) and Fusarium solani species complex (FSSC) are common etiologic agents of opportunistic mycoses. Their hyphae grow via apical extension followed by invasion of host epithelial surfaces, particularly corneal and epithelial tissues. Thigmotropism is the contact-sensing response of these growing hyphae to change the direction of their apical growth in response to changes in the topography of their contacted surfaces, such as clefts between adjacent host cells. Investigations of fungal thigmotropism among etiologic agents of opportunistic mycoses are sparse. In this study, we assessed thigmotropic capacities of 10 fusarial strains. Thigmotropic activity was quantified using a chemotaxicell system followed by scanning electron microscopy (SEM). Isolates belonging to the FSSC had significantly greater rates of thigmotropism than FOSC strains (p &lt; 0.0001). In summary, this work offers a creative method to assess thigmotropism, a crucial aspect of fungal pathogenesis, and, secondly, demonstrates potent thigmotropic capacities of fusarial isolates belonging to the FSSC.<\/jats:p>","DOI":"10.3390\/jof12050344","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T09:03:37Z","timestamp":1778144617000},"page":"344","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differential Thigmotropic Capacities Among Fusarial Isolates: Fusarium solani Species Complex (FSSC) Isolates Most Potent"],"prefix":"10.3390","volume":"12","author":[{"given":"Sehee I.","family":"Rim","sequence":"first","affiliation":[{"name":"Department of Microbiology, Miami University, Oxford, OH 45056, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew L.","family":"Duley","sequence":"additional","affiliation":[{"name":"Center for Advanced Microscopy & Imaging, Miami University, Oxford, OH 45056, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8109-8702","authenticated-orcid":false,"given":"Michael R.","family":"Hughes","sequence":"additional","affiliation":[{"name":"Statistical Consulting Center, Miami University, Oxford, OH 45056, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Jing","sequence":"additional","affiliation":[{"name":"Statistical Consulting Center, Miami University, Oxford, OH 45056, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia R.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Miami University, Oxford, OH 45056, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"ref_1","first-page":"Doc04","article-title":"Fusarium spp.: Infections and intoxications","volume":"12","author":"Hof","year":"2024","journal-title":"GMS Infect. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Kamil, D., Mishra, A.K., Das, A., and Nishmitha, K. (2025). Genus Fusarium and Fusarium species complexes. Biodiversity, Bioengineering, and Biotechnology of Fungi, Elsevier. [1st ed.].","DOI":"10.1016\/B978-0-443-13856-0.00016-6"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/mpp.12289","article-title":"The Fusarium solani species complex: Ubiquitous pathogens of agricultural importance","volume":"17","author":"Coleman","year":"2016","journal-title":"Mol. Plant Pathol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Jorgensen, J.H., Pfaller, M.A., Carroll, K.C., Funke, G., Landry, M.L., Richter, S.S., and Warnock, D.W. (2015). Fusarium and Other Opportunistic Hyaline Fungi. Manual of Clinical Microbiology, ASM Press. [11th ed.].","DOI":"10.1128\/9781555817381"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1128\/CMR.7.4.479","article-title":"Taxonomy, biology, and clinical aspects of Fusarium species","volume":"7","author":"Nelson","year":"1994","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1094\/PDIS.2003.87.2.117","article-title":"A Utilitarian Approach to Fusarium Identification","volume":"87","author":"Summerell","year":"2003","journal-title":"Plant Disaease"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.3852\/10-307","article-title":"New species from the Fusarium solani species complex derived from perithecia and soil in the old World tropics","volume":"103","author":"Nalim","year":"2011","journal-title":"Mycologia"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1001\/jamaophthalmol.2023.6825","article-title":"Prevalence and features of fungal keratitis among US patients with commercial health insurance","volume":"142","author":"Benedict","year":"2024","journal-title":"JAMA Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Scheel, C.M., Hurst, S.F., Barreiros, G., Akiti, T., Nucci, M., and Balajee, S.A. (2013). Molecular analyses of Fusarium isolates recovered from a cluster of invasive mold infections in a Brazilian hospital. BMC Infect. Dis., 13.","DOI":"10.1186\/1471-2334-13-49"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s11046-024-00874-x","article-title":"Fusarium keratitis: A systematic review (1969 to 2023)","volume":"189","author":"Cintra","year":"2024","journal-title":"Mycopathologia"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1167\/iovs.09-4237","article-title":"A murine model of contact lens-associated Fusarium keratitis","volume":"51","author":"Sun","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1086\/342328","article-title":"Cutaneous infection by Fusarium species in healthy and immunocompromised hosts: Implications for diagnosis and management","volume":"35","author":"Nucci","year":"2002","journal-title":"Clin. Infect. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1128\/CMR.00014-07","article-title":"Fusarium infections in immunocompromised patients","volume":"20","author":"Nucci","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1001\/jama.296.8.953","article-title":"Multistate outbreak of Fusarium keratitis associated with use of a contact lens solution","volume":"296","author":"Chang","year":"2006","journal-title":"JAMA"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Hoffman, J.J., Burton, M.J., and Leck, A. (2021). Mycotic keratitis\u2014A global threat from the filamentous fungi. J. Fungi, 7.","DOI":"10.3390\/jof7040273"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1097\/ICO.0b013e3181d8383a","article-title":"The molecular pathogenicity of Fusarium keratitis: A fungal transcriptional regulator promotes hyphal penetration of the cornea","volume":"29","author":"Hua","year":"2010","journal-title":"Cornea"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Hof, H. (2020). The medical relevance of Fusarium spp. J. Fungi, 6.","DOI":"10.3390\/jof6030117"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"308","DOI":"10.4103\/0019-5154.97680","article-title":"Fusarium solani: A causative agent of skin and nail infections","volume":"57","author":"Kuruvilla","year":"2012","journal-title":"Indian J. Dermatol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Uemura, E.V.G., Barbosa, M.D.S., Simionatto, S., Al-Harrasi, A., Al-Hatmi, A.M.S., and Rossato, L. (2022). Onychomycosis caused by Fusarium species. J. Fungi, 8.","DOI":"10.3390\/jof8040360"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1023\/B:MYCO.0000024186.32367.d4","article-title":"Onychomycosis caused by Fusarium solani and Fusarium oxysporum in S\u00e3o Paulo, Brazil","volume":"157","author":"Godoy","year":"2004","journal-title":"Mycopathologia"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"myae013","DOI":"10.1093\/mmy\/myae013","article-title":"Fusariosis in burn patients: A systematic review of case reports","volume":"62","author":"Piccoli","year":"2024","journal-title":"Med. Mycol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1086\/319753","article-title":"Fusarium infection after solid-organ transplantation","volume":"32","author":"Sampathkumar","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"ref_23","first-page":"645","article-title":"Invasive Fusarium infections in bone marrow transplant recipients","volume":"77","author":"Blazar","year":"1984","journal-title":"Am. J. Med. Genet."},{"key":"ref_24","first-page":"653","article-title":"Disseminated Fusarium infections in patients following bone marrow transplantation","volume":"4","author":"Minor","year":"1989","journal-title":"Bone Marrow Transpl."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s12281-014-0205-y","article-title":"Combat-related invasive fungal wound infections","volume":"8","author":"Tribble","year":"2014","journal-title":"Curr. Fungal Infect. Rep."},{"key":"ref_26","first-page":"618358","article-title":"Colonization of a central venous catheter by the hyaline fungus Fusarium solani species compex: A case report and SEM imaging","volume":"2013","author":"Columbo","year":"2013","journal-title":"Case Rep. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/BF01690988","article-title":"Opportunistic fusarial infections in humans","volume":"14","author":"Guarro","year":"1995","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"ofae631.1242","DOI":"10.1093\/ofid\/ofae631.1242","article-title":"P-1053. Invasive fusariosis: 5-year update from a single-center experience in the voriconazole era","volume":"12","author":"Kovac","year":"2025","journal-title":"Open Forum Infect. Dis."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0195-6701(97)90197-3","article-title":"Fungaemia due to Fusarium spp. in cancer patient","volume":"36","author":"Krcmery","year":"1997","journal-title":"J. Hosp. Infect."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1128\/JCM.02371-07","article-title":"Molecular phylogenetic diversity, multilocus haplotype nomenclature, and in vitro antifungal resistance within the Fusarium solani species complex","volume":"46","author":"Sutton","year":"2008","journal-title":"J. Clin. Microbiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1128\/JCM.00120-06","article-title":"Members of the Fusarium solani species complex that cause infections in both humans and plants are common in the environment","volume":"44","author":"Zhang","year":"2006","journal-title":"J. Clin. Microbiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1128\/AAC.00272-08","article-title":"Species distribution and in vitro antifungal susceptibility patterns of 75 clinical isolates of Fusarium spp. from northern Italy","volume":"52","author":"Tortorano","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1086\/324501","article-title":"Fusariosis associated with pathogenic Fusarium species colonization of a hospital water system: A new paradigm for the epidemiology of opportunistic mold infections","volume":"33","author":"Anaissie","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1462-2920.2007.01446.x","article-title":"Sewage and community shower drains are environmental reservoirs of Fusarium solani species complex group 1, a human and plant pathogen","volume":"10","author":"Mehl","year":"2008","journal-title":"Environ. Microbiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1094\/PDIS-06-24-1161-RE","article-title":"Diversity and characteristics of Fusarium solani species complex (FSSC) isolates causing collar rot and fruit rot of passion fruit in Taiwan","volume":"109","author":"Lo","year":"2025","journal-title":"Plant Dis."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"107237","DOI":"10.1016\/j.micpath.2024.107237","article-title":"Morphological, molecular and pathogenicity characteristics of Fusarium verticillioides causing Fusarium ear rot of corn in Panama","volume":"199","author":"Perez","year":"2025","journal-title":"Microb. Pathog."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.micpath.2014.01.002","article-title":"Molecular phylogenetic and pathogenetic characterization of Fusarium solani species complex (FSSC), the cause of dry rot on potato in Iran","volume":"67\u201368","author":"Chehri","year":"2014","journal-title":"Microb. Pathog."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1146\/annurev-phyto-080615-095919","article-title":"Fusarium oxysporum and the Fusarium wilt syndrome","volume":"55","author":"Gordon","year":"2017","journal-title":"Annu. Rev. Phytopathol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1094\/PHP-11-18-0075-RS","article-title":"Eight species of Fusarium cause root rot of corn (Zea mays) in South Dakota","volume":"20","author":"Okello","year":"2019","journal-title":"Plant Health Prog."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.funbio.2022.07.007","article-title":"Mechanism underlying the response of fungi and their Fusarium symbiotic networks to the rotations of soybean and corn","volume":"126","author":"Song","year":"2022","journal-title":"Fungal Biol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1017\/S0953756203008888","article-title":"New angles in mycology: Studies in directional growth and directional motility","volume":"108","author":"Gow","year":"2004","journal-title":"Mycol. Res."},{"key":"ref_42","first-page":"705","article-title":"Investigation of touch-sensitive responses by hyphae of the human pathogenic fungus Candida albicans","volume":"8","author":"Gow","year":"1994","journal-title":"Scanning Microsc."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.fgb.2006.11.012","article-title":"Induction of contour sensing in Aspergillus niger by stress and its relevance to fungal growth mechanics and hyphal tip structure","volume":"44","author":"Bowen","year":"2007","journal-title":"Fungal Genet. Biol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"fuaf009","DOI":"10.1093\/femsre\/fuaf009","article-title":"Electrical signaling in fungi: Past and present challenges","volume":"49","author":"Buffi","year":"2025","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"10.1128","DOI":"10.1128\/microbiolspec.FUNK-0040-2016","article-title":"Thigmo responses: The fungal sense of touch","volume":"5","author":"Almeida","year":"2017","journal-title":"Microbiol. Spectr."},{"key":"ref_46","first-page":"517","article-title":"Hyphal growth in human fungal pathogens and its role in virulence","volume":"1","author":"Brand","year":"2012","journal-title":"Int. J. Microbiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1080\/02681219780001301","article-title":"Contact-sensing by hyphae of dermatophytic and saprophytic fungi","volume":"35","author":"Perera","year":"1997","journal-title":"J. Med. Vet. Mycol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1099\/00221287-144-3-689","article-title":"Thigmotropism and stretch-activated channels in the pathogenic fungus Candida albicans","volume":"144","author":"Watts","year":"1998","journal-title":"Microbiology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1159\/000104260","article-title":"Fungal thigmotropism in onychomycosis and in a clear hydrogel pad model","volume":"215","author":"Quatresooz","year":"2007","journal-title":"Dermatology"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s12281-015-0225-2","article-title":"Diagnosis of Fusarium infections: Approaches to identification by the clinical mycology laboratory","volume":"9","author":"Brankovics","year":"2015","journal-title":"Curr. Fungal Infect. Rep."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1094\/PDIS-09-21-2035-SR","article-title":"DNA Sequence-Based Identification of Fusarium: A Work in Progress","volume":"106","author":"Whitaker","year":"2022","journal-title":"Plant Dis."},{"key":"ref_52","first-page":"100244","article-title":"Morphological and molecular characterization of Fusarium sp. causing wilt disease of isabgol (Plantago ovata Forsk.) and its management strategies","volume":"16","author":"Meena","year":"2020","journal-title":"J. Appl. Res. Med. Aromat. Plants"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.fgb.2009.08.006","article-title":"A two-locus DNA sequence database for typing plant and human pathogens within the Fusarium oxysporum species complex","volume":"46","author":"Gueidan","year":"2009","journal-title":"Fungal Genet. Biol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3708","DOI":"10.1128\/JCM.00989-10","article-title":"Internet-accessible DNA sequence database for identifying fusaria from human and animal infections","volume":"48","author":"Sutton","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1399-302X.1995.tb00128.x","article-title":"A novel method to study the hyphal phase of Candida albicans and to evaluate its hydrophobicity","volume":"10","author":"Nikawa","year":"1995","journal-title":"Oral. Microbiol. Immunol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1023\/A:1006849532064","article-title":"Quantification of thigmotropism (contact sensing) of Candida albicans and Candida tropicalis","volume":"138","author":"Nikawa","year":"1997","journal-title":"Mycopathologia"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0966-842X(93)90031-L","article-title":"Nonchemical signals used for host location and invasion by fungal pathogens","volume":"1","author":"Gow","year":"1993","journal-title":"Trends Microbiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/cmi.12369","article-title":"Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae","volume":"17","author":"Thomson","year":"2015","journal-title":"Cell. Microbiol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1099\/mic.0.000499","article-title":"Microbe profile: Candida albicans: A shape-changing, opportunistic pathogenic fungus of humans","volume":"163","author":"Gow","year":"2017","journal-title":"Microbiology"},{"key":"ref_60","first-page":"362784","article-title":"Thigmotropism of malignant melanoma cells","volume":"11","author":"Quatresooz","year":"2011","journal-title":"Dermatol. Res. Pract."},{"key":"ref_61","first-page":"100246","article-title":"Common virulence factors between Histoplasma and Paracoccidioides: Recognition of Hsp60 and Enolase by CR3 and plasmin receptors in host cells","volume":"7","author":"Echeverri","year":"2024","journal-title":"Curr. Res. Microb. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.13005\/bbra\/2598","article-title":"Cell surface hydrophobicity as a virulence factor in Candida albicans","volume":"14","author":"Goswami","year":"2017","journal-title":"Biosci. Biotechnol. Res. Asia"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Satala, D., Bras, G., Kozik, A., Rapala-Kozik, M., and Karkowska-Kuleta, J. (2023). More than just protein degradation: The regulatory roles and moonlighting functions of extracellular proteases produced by fungi pathogenic for humans. J. Fungi, 9.","DOI":"10.3390\/jof9010121"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s11033-024-09314-x","article-title":"A perspective on varied fungal virulence factors causing infection in host plants","volume":"51","author":"Kumar","year":"2024","journal-title":"Mol. Biol. Rep."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"127506","DOI":"10.1016\/j.micres.2023.127506","article-title":"Virulence factors of the genus Fusarium with targets in plants","volume":"277","year":"2023","journal-title":"Microbiol. Res."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.tree.2021.05.006","article-title":"Fungal behaviour: A new frontier in behavioural ecology","volume":"36","author":"Aleklett","year":"2021","journal-title":"Trends Ecol. Evol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1128\/JCM.39.4.1345-1347.2001","article-title":"Inoculum standardization for antifungal susceptibility testing of filamentous fungi pathogenic for humans","volume":"39","author":"Petrikkou","year":"2001","journal-title":"J. Clin. Micro."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"29708","DOI":"10.1038\/s41598-024-78195-8","article-title":"Molecular phylogeny and genetic diversity of Fusarium oxysporum from various hosts in Malaysia","volume":"14","author":"Nor","year":"2024","journal-title":"Sci. Rep."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2400104","DOI":"10.1002\/gch2.202400104","article-title":"Harnessing fungi signaling in living composites","volume":"8","author":"Schyck","year":"2024","journal-title":"Glob. Chall."},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Dekkerov\u00e0, J., and Cern\u00e0kov\u00e0, L. (2026). Inhibitory effect of verapamil in the treatment of mixed biofilm of Candida albicans and Staphylococcus aureus. Hygiene, 6.","DOI":"10.3390\/hygiene6010007"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nrmicro1960","article-title":"Molecular mechanisms of mechanosensing and their roles in fungal contact sensing","volume":"6","author":"Kumamoto","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_72","unstructured":"Kumar, A., and Jha, A. (2023). Anticandidal Therapeutics, Academic Press. [1st ed.]."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"103022","DOI":"10.1016\/j.pmpp.2025.103022","article-title":"Morphological and molecular basis of host specificity in fungal pathogens-An overview","volume":"141","author":"Kilaru","year":"2026","journal-title":"Physiol. Mol. Plant Pathol."}],"container-title":["Journal of Fungi"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2309-608X\/12\/5\/344\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T10:05:07Z","timestamp":1778148307000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2309-608X\/12\/5\/344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":73,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["jof12050344"],"URL":"https:\/\/doi.org\/10.3390\/jof12050344","relation":{},"ISSN":["2309-608X"],"issn-type":[{"value":"2309-608X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]}}}