{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T11:57:42Z","timestamp":1781697462755,"version":"3.54.5"},"reference-count":179,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Background: Mucormycosis is a life-threatening angioinvasive fungal infection that primarily affects immunocompromised individuals, especially those with diabetes mellitus or hematologic malignancies. Despite its clinical importance, a comprehensive synthesis of mucormycosis cases from T\u00fcrkiye is lacking. This study aimed to review and synthesize the published case reports on mucormycosis in T\u00fcrkiye systematically. Materials and Methods: Mucormycosis case reports from T\u00fcrkiye published between\u00a01\u00a0January 1966 and\u00a030\u00a0November 2024 were reviewed and analyzed, with an\u00a0emphasis on demographics, clinical characteristics, treatment strategies, and outcomes. Results: A total of 199 cases from 155 publications were included. Mean age was 47.7 years, and 51.8% of patients were male. Diabetes mellitus was the most frequent underlying condition (65.8%), followed by hematologic malignancies (16.6%). Rhino-cerebral involvement was the predominant clinical form (86.4%). Histopathological confirmation was reported in 91.0% of cases, whereas microbiological confirmation was available in 47.7%. Overall mortality was 43.7%. Surgical debridement was performed in 69.3% of cases, and crude mortality was lower among patients who underwent surgery than among those who did not. Liposomal amphotericin B was the most frequently reported antifungal agent. Conclusions: This study provides a national descriptive synthesis of published mucormycosis cases from T\u00fcrkiye over nearly six decades. The findings highlight the predominance of diabetes-associated rhino-cerebral disease, frequent reliance on histopathology, and the importance of combined medical\u2013surgical management in routine practice. Because the dataset is based on heterogeneous published case reports and case series spanning a long time period, treatment-outcome findings should be interpreted descriptively.<\/jats:p>","DOI":"10.3390\/jof12060443","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T10:19:53Z","timestamp":1781691593000},"page":"443","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Overview of Mucormycosis Cases in T\u00fcrkiye: A Cumulative Case Analysis"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8913-2314","authenticated-orcid":false,"given":"Melike","family":"Ya\u015far Duman","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Ege University, \u0130zmir 35100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egemen","family":"Bolat","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Ege University, \u0130zmir 35100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9756-7764","authenticated-orcid":false,"given":"Seyfi","family":"Durmaz","sequence":"additional","affiliation":[{"name":"Department of Employee Health and Safety, Faculty of Medicine, Ege University, \u0130zmir 35100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7282-5031","authenticated-orcid":false,"given":"Dilek Ye\u015fim","family":"Metin","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Ege University, \u0130zmir 35100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00fcleyha","family":"Hilmio\u011flu-Polat","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine, Ege University, \u0130zmir 35100, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"ref_1","unstructured":"CDC (2025, February 19). 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