{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:49:33Z","timestamp":1790704173204,"version":"4.1.0"},"reference-count":32,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Fungi","JoF"],"abstract":"<jats:p>Candidozyma auris (formerly Candida auris) is a critical-priority multidrug-resistant pathogen. Comparative clinical data on first-line echinocandins\u2014micafungin and anidulafungin\u2014in C. auris candidemia remain limited. This retrospective cohort study compared clinical outcomes of micafungin and anidulafungin in adult patients with C. auris candidemia treated between January 2024 and December 2025 at three affiliated hospital campuses in Istanbul, T\u00fcrkiye. Propensity score matching (PSM) using a 1:1 nearest-neighbor algorithm was performed to balance baseline characteristics. Outcomes included 30-day (primary) and 14-day all-cause mortality, microbiological response, end-of-therapy (EOT) response, relapse, and drug-induced liver injury assessed by the Roussel Uclaf Causality Assessment Method (RUCAM). Among 154 included patients (micafungin, n = 94; anidulafungin, n = 60), no echinocandin resistance was detected. After PSM (55 matched pairs), 30-day all-cause mortality was identical between groups (41.8% vs. 41.8%; mOR 1.00, 95% CI 0.43\u20132.31; p = 1.000). Fourteen-day all-cause mortality (16.4% vs. 18.2%; p = 0.763), microbiological response (94.5% vs. 90.9%; p = 0.480), EOT response (74.5% vs. 67.3%; p = 0.346), and relapse (12.7% vs. 10.9%; p = 0.763) did not differ significantly between groups. RUCAM-based hepatic safety profiles were descriptively comparable. Micafungin and anidulafungin showed comparable observed outcomes in C. auris candidemia in this cohort.<\/jats:p>","DOI":"10.3390\/jof12070537","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T09:20:39Z","timestamp":1784712039000},"page":"537","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Outcomes of Micafungin and Anidulafungin in Candidozyma auris (Formerly Candida auris) Candidemia: A Propensity Score-Matched Retrospective Cohort Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5490-465X","authenticated-orcid":false,"given":"Ey\u00fcp","family":"Arslan","sequence":"first","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4245-1534","authenticated-orcid":false,"given":"\u00d6mer","family":"Kara\u015fahin","sequence":"additional","affiliation":[{"name":"Erzurum Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Erzurum 25040, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7858-6705","authenticated-orcid":false,"given":"Bet\u00fcl Y\u00fcsra","family":"\u015eirin","sequence":"additional","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Anesthesiology and Reanimation, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7943-7536","authenticated-orcid":false,"given":"Deniz","family":"Turan","sequence":"additional","affiliation":[{"name":"Haydarpa\u015fa Numune Training and Research Hospital, Laboratory of Medical Microbiology, University of Health Sciences, Istanbul 34668, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y\u0131ld\u0131z","family":"Ol\u00e7ar","sequence":"additional","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umut","family":"Elmas","sequence":"additional","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4657-5291","authenticated-orcid":false,"given":"Fatma","family":"Y\u0131lmaz Karada\u011f","sequence":"additional","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derya","family":"\u00d6zt\u00fcrk Engin","sequence":"additional","affiliation":[{"name":"Sancaktepe \u015eehit Prof. Dr. \u0130lhan Varank Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Istanbul 34785, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol. 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